38 results on '"Ieiri, Ichiro"'
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2. Population Pharmacokinetic Analysis of Drug–Drug Interactions Between Perampanel and Carbamazepine Using Enzyme Induction Model in Epileptic Patients
3. Optimal teicoplanin dosing regimen in neonates and children developed by leveraging real-world clinical information
4. Differences in Theophylline Clearance between Patients with Chronic Hepatitis and those with Liver Cirrhosis
5. Population Pharmacokinetic Analysis of Phenytoin After Intravenous Administration of Fosphenytoin in Adult and Elderly Epileptic Patients
6. Population Pharmacodynamic Analysis of Uric Acid–Lowering Effects of Febuxostat Based on Electronic Medical Records in Two Hospitals
7. Characterization of ADME gene variation in 21 populations by exome sequencing
8. Sulfasalazine disposition in a subject with 376C>T (nonsense mutation) and 421C>A variants in the ABCG2 gene
9. Population pharmacodynamic analysis of LDL-cholesterol lowering effects by statins and co-medications based on electronic medical records
10. Neonatal Dubin–Johnson syndrome: Novel compound heterozygous mutation in the ABCC2 gene
11. Modeling and simulation of bone mineral density response from a phase 2 study of ONO-5334, a new cathepsin K inhibitor, to support dose selection in osteoporosis
12. Influences of artificial heart-lung machine operation on the binding sites of albumin: Possibility of an effective administration plan
13. Population Pharmacokinetic and Pharmacodynamic Modeling of Different Formulations of ONO-5334, Cathepsin K Inhibitor, in Caucasian and Japanese Postmenopausal Females
14. Clinical impact of genetic variants of drug transporters in different ethnic groups within and across regions
15. Mechanisms of Pharmacokinetic Enhancement Between Ritonavir and Saquinavir; Micro/Small Dosing Tests Using Midazolam (CYP3A4), Fexofenadine (p-Glycoprotein), and Pravastatin (OATP1B1) as Probe Drugs
16. Apple juice greatly reduces systemic exposure to atenolol
17. Psychotropic Drug-Drug Interactions Involving P-Glycoprotein
18. Psychotropic Drug-Drug Interactions Involving P-Glycoprotein
19. Microdosing Clinical Study: Pharmacokinetic, Pharmacogenomic (SLCO2B1), and Interaction (Grapefruit Juice) Profiles of Celiprolol Following the Oral Microdose and Therapeutic Dose
20. Pharmacokinetic interaction study of sulphasalazine in healthy subjects and the impact of curcumin as an in vivo inhibitor of BCRP
21. Population pharmacokinetics of tamsulosin hydrochloride in paediatric patients with neuropathic and non-neuropathic bladder
22. Usefulness of serum cystatin C to determine the dose of vancomycin in critically ill patients
23. Warfarin-dosing algorithm based on a population pharmacokinetic/pharmacodynamic model combined with Bayesian forecasting
24. Quantitative Population Pharmacokinetic Analysis of Pravastatin Using an Enterohepatic Circulation Model Combined With Pharmacogenomic Information on SLCO1B1 and ABCC2 Polymorphisms
25. Polymorphism in human organic cation transporters and metformin action
26. Effects of organic anion transporting polypeptide 1B1 haplotype on pharmacokinetics of pravastatin, valsartan, and temocapril
27. Allelic expression imbalance of the human CYP3A4 gene and individual phenotypic status
28. Functional Analysis of SNPs Variants of BCRP/ABCG2
29. Characterization of the Cellular Localization, Expression Level, and Function of SNP Variants of MRP2/ABCC2
30. The MDR1 (ABCB1) Gene Polymorphism and its Clinical Implications
31. Polymorphisms of OATP-C (SLC21A6) and OAT3 (SLC22A8) genes: Consequences for pravastatin pharmacokinetics
32. The Antiplatelet Aggregation Effects of Aspirin Suppositories
33. Role of human MDR1 gene polymorphism in bioavailability and interaction of digoxin, a substrate of P-glycoprotein
34. Genetic polymorphisms and functional characterization of the 5′-flanking region of the human CYP2C9 gene: In vitro and in vivo studies
35. Reliability of the omeprazole hydroxylation index for CYP2C19 phenotyping: possible effect of age, liver disease and length of therapy
36. The Effects of Genetic Polymorphisms of CYP2C9 and CYP2C19 on Phenytoin Metabolism in Japanese Adult Patients with Epilepsy: Studies in Stereoselective Hydroxylation and Population Pharmacokinetics
37. Stereoselective 4'-Hydroxylation of Phenytoin: Relationship to CYP2C19 Polymorphism
38. Pharmacokinetics of omeprazole (a substrate of CYP2C19) and comparison with two mutant alleles, CYP2C19m1 in exon 5 and CYP2C19m2 in exon 4, in Japanese subjects
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