51 results on '"Cantley, Lewis C."'
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2. PTEN loss is a context-dependent outcome determinant in obese and non-obese endometrioid endometrial cancer patients
3. Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function
4. Idelalisib — A PI3Kδ Inhibitor for B-Cell Cancers
5. Metabolic syndrome: F stands for fructose and fat
6. Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway
7. Influence of Threonine Metabolism on S-Adenosylmethionine and Histone Methylation
8. Ancient Sensor for Ancient Drug
9. Exon-centric regulation of pyruvate kinase M alternative splicing via mutually exclusive exons
10. A murine lung cancer co-clinical trial identifies genetic modifiers of therapeutic response
11. Inhibition of Pyruvate Kinase M2 by Reactive Oxygen Species Contributes to Cellular Antioxidant Responses
12. PHGDH amplification and altered glucose metabolism in human melanoma
13. Receptor tyrosine kinases exert dominant control over PI3K signaling in human KRAS mutant colorectal cancers
14. Phosphoproteomic Analysis Identifies Grb10 as an mTORC1 Substrate That Negatively Regulates Insulin Signaling
15. Evidence for an Alternative Glycolytic Pathway in Rapidly Proliferating Cells
16. Identification of small molecule inhibitors of pyruvate kinase M2
17. Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
18. Phosphatidyl Inositol 3-Kinase Signaling in Hypothalamic Proopiomelanocortin Neurons Contributes to the Regulation of Glucose Homeostasis
19. Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
20. Biomolecular Characterization and Protein Sequences of the Campanian Hadrosaur B. canadensis
21. Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancer
22. Acute effects of leptin require PI3K signaling in hypothalamic proopiomelanocortin neurons in mice
23. Molecular Phylogenetics of Mastodon and Tyrannosaurus rex
24. The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth
25. Pyruvate kinase M2 is a phosphotyrosine-binding protein
26. PI3K Charges Ahead
27. MET Amplification Leads to Gefitinib Resistance in Lung Cancer by Activating ERBB3 Signaling
28. Protein Sequences from Mastodon and Tyrannosaurus Rex Revealed by Mass Spectrometry
29. AKT1 Overexpression in Endothelial Cells Leads to the Development of Cutaneous Vascular Malformations In Vivo
30. Allelic dilution obscures detection of a biologically significant resistance mutation in EGFR-amplified lung cancer
31. Role of Class IA PI 3-Kinase in Pancreatic β Cells: 1569-P
32. Ras, PI(3)K and mTOR signalling controls tumour cell growth
33. The Kinase LKB1 Mediates Glucose Homeostasis in Liver and Therapeutic Effects of Metformin
34. Differential Effects of Gefitinib and Cetuximab on Non–small-cell Lung Cancers Bearing Epidermal Growth Factor Receptor Mutations
35. Differential regulation of the phosphoinositide 3-kinase and MAP kinase pathways by hepatocyte growth factor vs. insulin-like growth factor-I in myogenic cells
36. Proteomic Screen Finds pSer/pThr-Binding Domain Localizing Plk1 to Mitotic Substrates
37. Reduced expression of the murine p85α subunit of phosphoinositide 3-kinase improves insulin signaling and ameliorates diabetes
38. Phosphatidylinositol 3-kinase-dependent activation of trypsinogen modulates the severity of acute pancreatitis
39. Translocating Tubby
40. Signal transduction: Grabbing phosphoproteins
41. Affinity-Driven Peptide Selection of an NFAT Inhibitor More Selective Than Cyclosporin A
42. Impaired B Cell Development and Proliferation in Absence of Phosphoinositide 3-Kinase p85[small alpha, Greek]
43. Corequirement of Specific Phosphoinositides and Small GTP-binding Protein Cdc42 in Inducing Actin Assembly in Xenopus Egg Extracts
44. SRPK2: A Differentially Expressed SR Protein-specific Kinase Involved in Mediating the Interaction and Localization of Pre-mRNA Splicing Factors in Mammalian Cells
45. Sequence-Specific and Phosphorylation-Dependent Proline Isomerization: A Potential Mitotic Regulatory Mechanism
46. A new pathway for synthesis of phosphatidylinositol-4,5-bisphosphate
47. Apoptosis: A Bad kinase makes good
48. Transformation of Chicken Cells by the Gene Encoding the Catalytic Subunit of PI 3-Kinase
49. Direct Regulation of the Akt Proto-Oncogene Product by Phosphatidylinositol-3,4-bisphosphate
50. Catalytic specificity of protein-tyrosine kinases is critical for selective signalling
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