96 results on '"Amidon, Gordon L."'
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2. Exploring gastrointestinal variables affecting drug and formulation behavior: Methodologies, challenges and opportunities
3. In vitro dissolution methodology, mini-Gastrointestinal Simulator (mGIS), predicts better in vivo dissolution of a weak base drug, dasatinib
4. Bio-predictive tablet disintegration: Effect of water diffusivity, fluid flow, food composition and test conditions
5. The Biopharmaceutics Classification System: Subclasses for in vivo predictive dissolution (IPD) methodology and IVIVC
6. The development of orally administrable gemcitabine prodrugs with d-enantiomer amino acids: Enhanced membrane permeability and enzymatic stability
7. Mechanistic analysis of solute transport in an in vitro physiological two-phase dissolution apparatus
8. In silico prediction of drug dissolution and absorption with variation in intestinal pH for BCS class II weak acid drugs: ibuprofen and ketoprofen
9. Mechanistic investigation of food effect on disintegration and dissolution of BCS class III compound solid formulations: the importance of viscosity
10. Potential of Amino Acid/Dipeptide Monoester Prodrugs of Floxuridine in Facilitating Enhanced Delivery of Active Drug to Interior Sites of Tumors: A Two-Tier Monolayer In Vitro Study
11. Drug targeting strategies for the treatment of inflammatory bowel disease: a mechanistic update
12. Puromycin-sensitive aminopeptidase: An antiviral prodrug activating enzyme
13. MRP2 mediated drug–drug interaction: Indomethacin increases sulfasalazine absorption in the small intestine, potentially decreasing its colonic targeting
14. Comparative Gene Expression of Intestinal Metabolizing Enzymes
15. Intestinal Dipeptide Absorption Is Preserved During Thermal Injury and Cytokine Treatment
16. Quasi-equilibrium analysis of the ion-pair mediated membrane transport of low-permeability drugs
17. Grapefruit Juice and its Constituents Augment Colchicine Intestinal Absorption: Potential Hazardous Interaction and the Role of P-Glycoprotein
18. Lack of Interaction Between the Peptidomimetic Substrates Captopril and Cephradine
19. Interferon-γ increases expression of the di/tri-peptide transporter, h-PEPT1, and dipeptide transport in cultured human intestinal monolayers
20. Segmental-dependent membrane permeability along the intestine following oral drug administration: Evaluation of a triple single-pass intestinal perfusion (TSPIP) approach in the rat
21. Mechanistic understanding of time-dependent oral absorption based on gastric motor activity in humans
22. Pharmacokinetics of the CYP 3A Substrate Simvastatin following Administration of Delayed Versus Immediate Release Oral Dosage Forms
23. The Use of BDDCS in Classifying the Permeability of Marketed Drugs
24. Possibility of enterohepatic recycling of ketoprofen in dogs
25. Proline prodrug of melphalan, prophalan-L, demonstrates high therapeutic index in a murine melanoma model
26. Comparative gene expression profiles of intestinal transporters in mice, rats and humans
27. Proline Prodrug of Melphalan Targeted to Prolidase, a Prodrug Activating Enzyme Overexpressed in Melanoma
28. Solubilization and dissolution of insoluble weak acid, ketoprofen: Effects of pH combined with surfactant
29. Why is it Challenging to Predict Intestinal Drug Absorption and Oral Bioavailability in Human Using Rat Model
30. Stability of valacyclovir: Implications for its oral bioavailability
31. Identification and Proposed Mechanism of Antiviral Nucleoside Metabolism by DNA Repair Enzymes: 15
32. Feasibility of Biowaiver Extension to Biopharmaceutics Classification System Class III Drug Products: Cimetidine
33. Floxuridine Amino Acid Ester Prodrugs: Enhancing Caco-2 Permeability and Resistance to Glycosidic Bond Metabolism
34. Identification and Proposed Mechanism of Antiviral Nucleoside Metabolism by DNA Repair Enzymes: 15
35. Pharmacokinetics of an immediate release, a controlled release and a two pulse dosage form in dogs
36. Feasibility studies of utilizing disk intrinsic dissolution rate to classify drugs
37. A Fluorescent hPept1 Transporter Substrate for Uptake Screening
38. Amino Acid Ester Prodrugs of Floxuridine: Synthesis and Effects of Structure, Stereochemistry, and Site of Esterification on the Rate of Hydrolysis
39. Polymer degradation and in vitro release of a model protein from poly(D,L-lactide-co-glycolide) nano- and microparticles
40. Human Jejunal Permeability of Cyclosporin A: Influence of Surfactants on P-Glycoprotein Efflux in Caco-2 Cells
41. Comparison of Human Duodenum and Caco-2 Gene Expression Profiles for 12,000 Gene Sequences Tags and Correlation with Permeability of 26 Drugs
42. Biopharmaceutics Classification System: The Scientific Basis for Biowaiver Extensions1
43. A Mechanistic Approach to Understanding the Factors Affecting Drug Absorption: A Review of Fundamentals
44. Human Jejunal Permeability of Two Polar Drugs: Cimetidine and Ranitidine
45. Time-Dependent Oral Absorption Models
46. Dissolution Testing as a Prognostic Tool for Oral Drug Absorption: Dissolution Behavior of Glibenclamide
47. Evidence for Overlapping Substrate Specificity Between Large Neutral Amino Acid (LNAA) and Dipeptide (hPEPTl) Transporters for PD 158473, an NMDA Antagonist
48. The Effect of In Vivo Dissolution, Gastric Emptying Rate, and Intestinal Transit Time on the Peak Concentration and Area-Under-the-Curve of Drugs with Different Gastrointestinal Permeabilities
49. Letter to the Editor
50. Intestinal Transport of Gentamicin with a Novel, Glycosteroid Drug Transport Agent
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