226 results on '"Alkylation"'
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2. Methanococcus vannielii Selenium-Binding Protein (SeBP): Chemical Reactivity of Recombinant SeBP Produced in Escherichia coli
3. 1,2-Bis(Methylsulfonyl)-1-(2-Chloroethyl)-2-[[1-(4-Nitrophenyl)Ethoxy]Carbonyl]Hydrazine: An Anticancer Agent Targeting Hypoxic Cells
4. A Bifunctional DNA Repair Protein from Ferroplasma acidarmanus Exhibits O 6 -Alkylguanine- DNA Alkyltransferase and Endonuclease V Activities
5. Efficient Construction of the Securine A Carbon Skeleton
6. Contiguous Stereogenic Quaternary Carbons: A Daunting Challenge in Natural Products Synthesis
7. Binding Affinity of Lactose Permease Is Not Altered by the H + Electrochemical Gradient
8. Stereoselective Terminal Functionalization of Small Peptides for Catalytic Asymmetric Synthesis of Unnatural Peptides
9. Mechanistic Studies of the Molybdenum-Catalyzed Asymmetric Alkylation Reaction
10. Solid-Phase Synthesis of Chiral 3,4-Diazaphospholanes and Their Application to Catalytic Asymmetric Allylic Alkylation
11. OH-Pd(0) Interaction as a Stabilizing Factor in Palladium-Catalyzed Allylic Alkylations
12. Enantioselective Syntheses and Biological Studies of Aeruginosin 298-A and Its Analogs: Application of Catalytic Asymmetric Phase-Transfer Reaction
13. A General Strategy for Target-Promoted Alkylation in Biological Systems
14. The Dual Nature of Human Extracellular Superoxide Dismutase: One Sequence and Two Structures
15. Role and Location of the Unusual Redox-Active Cysteines in the Hydrophobic Domain of the Transmembrane Electron Transporter DsbD
16. Synthetic Modeling of Zinc Thiolates: Quantitative Assessment of Hydrogen Bonding in Modulating Sulfur Alkylation Rates
17. Enhancing Polyethylenimine's Delivery of Plasmid DNA into Mammalian Cells
18. DNA Replication Is Required for the Checkpoint Response to Damaged DNA in Xenopus Egg Extracts
19. Changing the Lactose Permease of Escherichia coli into a Galactose-Specific Symporter
20. In vivo Mechanism-Based Inactivation of S-Adenosylmethionine Decarboxylases from Escherichia coli, Salmonella typhimurium, and Saccharomyces cerevisiae
21. Biosynthesis of the Thiazole Moiety of Thiamin in Escherichia coli: Identification of an Acyldisulfide-Linked Protein-Protein Conjugate That is Functionally Analogous to the Ubiquitin/E1 Complex
22. Viral Capsid Mobility: A Dynamic Conduit for Inactivation
23. Unraveling the Mechanism of the Lactose Permease of Escherichia coli
24. Simultaneous Measurement of ΔpH and Electron Transport in Chloroplast Thylakoids by 9-Aminoacridine Fluorescence
25. Structure and Mechanism of Mammalian Thioredoxin Reductase: The Active Site Is a Redox-Active Selenolthiol/Selenenylsulfide Formed from the Conserved Cysteine-Selenocysteine Sequence
26. Induction of Heat Shock Protein 70 by Herbimycin A and Cyclopentenone Prostaglandins in Smooth Muscle Cells
27. Mammalian Thioredoxin Reductase: Oxidation of the C-terminal Cysteine/Selenocysteine Active Site Forms a Thioselenide, and Replacement of Selenium with Sulfur Markedly Reduces Catalytic Activity
28. Biochemical Methods in Cultural Heritage Conservation Studies: An Alkylation Enzyme, S-Adenosylmethionine Transmethylase
29. Mechanism-Based Inhibition of the Melatonin Rhythm Enzyme: Pharmacologic Exploitation of Active Site Functional Plasticity
30. Poisoning of Human DNA Topoisomerase I by Ecteinascidin 743, an Anticancer Drug That Selectively Alkylates DNA in the Minor Groove
31. Phthalascidin, a Synthetic Antitumor Agent with Potency and Mode of Action Comparable to Ecteinascidin 743
32. Topoisomerase II-Mediated Site-Directed Alkylation of DNA by Psorospermin and its Use in Mapping other Topoisomerase II Poison Binding Sites
33. Human Thioredoxin Reductase from HeLa cells: Selective Alkylation of Selenocysteine in the Protein Inhibits Enzyme Activity and Reduction with NADPH Influences Affinity to Heparin
34. Tissues of MSH2-Deficient Mice Demonstrate Hypermutability on Exposure to a DNA Methylating Agent
35. Modification of Sulfhydryl Groups in the γ-Subunit of Chloroplast-Coupling Factor 1 Affects the Proton Slip through the ATP Synthase
36. Benzo[a]pyrene Diol Epoxide-DNA Cis Adduct Formation through a Trans Chlorohydrin Intermediate
37. Coelenterate Cnidae Capsules: Disulfide Linkages Revealed by Silver Cytochemistry and Their Differential Responses to Thiol Reagents
38. Distamycin A Modulates the Sequence Specificity of DNA Alkylation by Duocarmycin A
39. The Fifth Epidermal Growth Factor-Like Domain of Thrombomodulin does not have an Epidermal Growth Factor-Like Disulfide Bonding Pattern
40. Lack of the DNA Repair Protein O6-Methylguanine-DNA Methyltransferase in Histologically Normal Brain Adjacent to Primary Human Brain Tumors
41. Catalytic Asymmetric Addition of Diphenylzinc to Cyclic α,β-Unsaturated Ketones
42. Regioselective ketone α-alkylation with simple olefins via dual activation
43. Attempted Hydrogen-Deuterium Exchange of the Protio-Trimethyloxonium Dication (CH 3 ) 3 OH 2+ , Study of Methylating Ability of (CH 3 ) 3 O + in Superacids and Theoretical Investigations
44. Inhalation Exposure of Rats and Mice to 1,3-Butadiene Induces N 6 -Adenine Adducts of Epoxybutene Detected by 32 P-Postlabeling and HPLC
45. Pattern recognition analysis in complex molecule synthesis and the preparation of iso-Diels–Alder motifs
46. Trp replacements for tightly interacting Gly–Gly pairs in LacY stabilize an outward-facing conformation
47. Adding Aliphatic C-H Bond Oxidations to Synthesis
48. Selective Catalytic C—H Alkylation of Alkenes with Alcohols
49. Structural and kinetic mapping of side-chain exposure onto the protein energy landscape
50. Crystal structure of lactose permease in complex with an affinity inactivator yields unique insight into sugar recognition
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