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1. Characterization of the heptad repeat regions, HR1 and HR2, and design of a fusion core structure model of the spike protein from severe acute respiratory syndrome (SARS) coronavirus

Author

Yanhui Xu, Jieqing Zhu, Yiwei Liu, Zhiyong Lou, Fang Yuan, Yueyong Liu, Cole, David K., Ling Ni, Nan Su, Lan Qin, Zhihong Bai, Xu Li, Bell, John I., Hai Pang, Po Tien, Gao, George F., and Zihe Rao

Subjects
Proteins -- Research, Biochemistry -- Research, Severe acute respiratory syndrome -- Research, Biological sciences, Chemistry
Abstract

The region of HR1 that binds to HR2 by a series of biochemical and biophysical measures is investigated. It shows the construction homology model for severe acute respiratory syndrome (SARS) coronavirus fusion core based on biochemical analysis and determines the mouse hepatitis virus (MHV) fusion core structure.

Published
2004

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