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1. The nature of major histocompatibility complex recognition by gamma delta T cells

Author

Schild, Hansjorg, Mavaddat, Nasim, Litzenberger, Christa, Ehrich, Elliot W., Davis, Mark M., Bluestone, Jeffrey A., Matis, Louis, Draper, Rockford K., and Yueh-hsiu Chien

Subjects
Major histocompatibility complex -- Research, T cells -- Analysis, Antigenic determinants -- Research, Cellular immunity -- Research, Biological sciences
Abstract

The topology of MHC recognition in gamma-delta T cells is unique and differs from the mechanism involved in alpha-beta T cell recognition. Class I and Class II antigen processing does not activate gamma-delta T cell clones LBK5 and G8, and peptides do not induce specificity. The surface expression of ligands on stimulator cells is crucial for G8 reactivity.

Published
1994

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