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Few if any issues engender such passionate--often acrimonious--disagreement among clinicians, ethicists, statisticians, and representatives of patient groups as does the continuing debate about informed consent and clinical research trials. In [...]

Postmarketing research, often called phase IV trials, is intended to familiarise doctors and patients with newly approved drugs. La Puma and colleagues, in Chicago, studied doctors' and patients' attitudes to [...]

Despite improvements in oral and dental hygiene together with a greater understanding of the pathogenesis of head and neck cancers, these tumours remain numerically important throughout the world and are [...]

The past 20 years have seen a welcome change from the traditional paternalist view of the patient as passive recipient of medical advice. This development results from the increasing range […]

This has become the new gold standard--whatever the primary site For many decades the primary treatment for common cancers has mostly been radical surgical resection (for example, for cancers of [...]

It may have been obvious to her at the time, but somehow I did not quite like to admit to Sylvia that she was my very first--patient, that is. I [...]

After the 1988 tragedy at Exeter, in which over 200 cancer patients received a radiation dose 25% too high, many radiotherapists wondered whether a systematic radiation underdosage might be taking [...]

In 1987 a young American journalist, leafing through files tucked away in a military archive, unexpectedly turned up evidence of deliberate injections of radioactive plutonium in unsuspecting patients. She telephoned [...]