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Your search keyword '"Tiveljung-Lindell, Annika"' showing total 5 results
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5 results on '"Tiveljung-Lindell, Annika"'

1. Etiology of community-acquired pneumonia: increased microbiological yield with new diagnostic methods

Author

Johansson, Niclas, Kalin, Mats, Tiveljung-Lindell, Annika, Giske, Christian G., and Hedlund, Jonas

Subjects
Community-acquired infections -- Causes of, Community-acquired infections -- Demographic aspects, Community-acquired infections -- Research, Bacterial pneumonia -- Causes of, Bacterial pneumonia -- Demographic aspects, Bacterial pneumonia -- Diagnosis, Bacterial pneumonia -- Research, Pneumonia -- Causes of, Pneumonia -- Demographic aspects, Pneumonia -- Diagnosis, Pneumonia -- Research, Polymerase chain reaction -- Usage, Health, Health care industry
Published
2010

2. Human bocavirus and acute wheezing in children

Author

Allander, Tobias, Jartti, Tuomas, Gupta, Shawon, Niesters, Hubert G.M., Lehtinen, Pasi, Osterback, Riikka, Vuorinen, Tytti, Waris, Matti, Bjerkner, Annelie, Tiveljung-Lindell, Annika, Hoogen, Bernadette G. van den, Hyypia, Timo, and Ruuskanen, Olli

Subjects
Parvoviruses -- Research, Wheeze -- Causes of, Pediatric respiratory diseases -- Causes of, Pediatric respiratory diseases -- Research, Health, Health care industry
Published
2007

3. Cloning of a human parvovirus by molecular screening of respiratory tract samples

Author

Allander, Tobias, Tammi, Martti T., Eriksson, Margareta, Bjerkner, Annelie, Tiveljung-Lindell, Annika, and Andersson, Bjorn

Subjects
Respiratory tract infections -- Research, Computational biology -- Research, Parvoviruses -- Research, Science and technology
Abstract

The identification of new virus species is a key issue for the study of infectious disease but is technically very difficult. We developed a system for large-scale molecular virus screening of clinical samples based on host DNA depletion, random PCR amplification, large-scale sequencing, and bioinformatics. The technology was applied to pooled human respiratory tract samples. The first experiments detected seven human virus species without the use of any specific reagent. Among the detected viruses were one coronavirus and one parvovirus, both of which were at that time uncharacterized. The parvovirus, provisionally named human bocavirus, was in a retrospective clinical study detected in 17 additional patients and associated with lower respiratory tract infections in children. The molecular virus screening procedure provides a general culture-independent solution to the problem of detecting unknown virus species in single or pooled samples. We suggest that a systematic exploration of the viruses that infect humans, 'the human virome,' can be initiated. bioinformatics | nucleotide sequencing | respiratory tract infection | virus

Published
2005

4. High occurrence of a new variant of chlamydia trachomatis escaping diagnostic tests among STI clinic patients in Stockholm, Sweden

Author

Marions, Lena, Rotzen-Ostlund, Maria, Grillner, Lena, Edgardh, Karin, Tiveljung-Lindell, Annika, Wikstrom, Arne, and Lidbrink, Peter

Subjects
Roche Holding Ltd., Sexually transmitted diseases -- Diagnosis, Pharmaceutical industry, Medical tests, Chlamydia, Health
Abstract

Background: In 2006, a genetic variant of Chlamydia trachomatis not detectable with the most commonly used diagnostic tests was identified. Initial reports suggested that as many as 10% to 13% of all chlamydia cases would have remained undiagnosed. The aim of the study was to find the occurrence and clinical findings of this genetic variant among a high-risk population in Stockholm, Sweden. Methods: Samples were analyzed using the Cobas TaqMan CT test (Roche Diagnostics). To detect the new variant, an additional PCR-analysis, artus C. trachomatis LC MOMP PCR Kit (Qiagen) was performed on all negative samples. Positive results in the artus test were confirmed by a mutant specific PCR. Clinical data were retrospectively collected from medical records. Results: Among 1009 samples analyzed, 115 were positive for C. trachomatis and among those, 27 were found to belong to the genetic altered strain. This variant constituted 23% of all chlamydia cases diagnosed, and 29% were found in the age group 20 to 29 years. Women with the new variant were younger and had more often performed another chlamydia test within the previous 6 months compared with those infected with the wild type. Conclusion: These results indicate that a large number of sexually active individuals might be infected despite a negative chlamydia test, thus facilitating a rapid transmission of the new variant. Accordingly, it is of great importance to be aware of limitations of the diagnostic methods used.

Published
2008

5. Merkel cell polyomavirus in respiratory tract secretions

Author

Goh, Shan, Lindau, Cecilia, Tiveljung-Lindell, Annika, and Allander, Tobias

Subjects
Identification and classification, Diagnosis, Research, Health aspects, Causes of, Polymerase chain reaction -- Research -- Health aspects, Polyomavirus -- Identification and classification -- Health aspects -- Research, Skin cancer -- Causes of -- Diagnosis -- Research, Polyoma virus -- Identification and classification -- Health aspects -- Research
Abstract

Merkel cell polyomavirus (MCPyV), associated with Merkel cell carcinoma, was detected in 27 of 635 nasopharyngeal aspirate samples by real-time PCR. MCPyV was more commonly found in adults than in [...]

Published
2009

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