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3 results on '"Takemasa, Tohru"'

1. Factors inducing codistribution of marginal actin fibers and fibronectin in rat aortic endothelial cells

Author

Sugimoto, Keiji, Fujii, Sachiko, Takemasa, Tohru, and Yamashita, Kazuo

Subjects
Vascular endothelium -- Physiological aspects, Fibronectins -- Physiological aspects, Actin -- Physiological aspects, Cytoskeletal proteins -- Physiological aspects, Hemodynamics -- Physiological aspects, Biological sciences
Abstract

Rheological techniques were utilized to determine the biological changes that occur in response to the codistribution of marginal actin fibers and subendothelial fibronectin in the endothelial cells of developing rat aorta. Analysis of fetal rat aortic endothelial cells indicated the role of increased tensile force and shear stress in inducing the codistribution of actin fibers and subendothelial fibronectin in developing rat aorta. Furthermore, the actin fibers, subendothelial fibronectin and stress fibers maintained the structural integrity of vascular endothelial cells.

Published
1997

2. Calcineurin-mediated slow-type fiber expression and growth in reloading condition

Author

Miyazaki, Mitsunori, Hitomi, Yoshiaki, Katsumura, Toshihito, Ohno, Hideki, Haga, Shukoh; Takemasa, Tohru, and Kizaki, Takako

Subjects
Calcineurin -- Health aspects, Muscles -- Health aspects, Health, Sports and fitness
Abstract

Experimental models of suspension and reloading were used to examine the effects of load-bearing conditions on skeletal muscle fiber type and size. The results demonstrate that reloading-induced fiber-type reversion toward a slow profile in the mice soleus muscle is prevented by the administration of FK506.

Published
2006

3. Intermittent reloading attenuates muscle atrophy through modulating Akt/mTOR pathway

Author

Miyazaki, Mitsunori, Noguchi, Miho, and Takemasa, Tohru

Subjects
Muscles -- Physiological aspects, Atrophy, Muscular -- Physiological aspects, Health, Sports and fitness
Abstract

A study investigates the impact of intermittent reloading (IR) during hindlimb unloading (HU) on the signaling pathways involved in reduction of skeletal muscle atrophy. Results suggest that IR-induced reduction of skeletal muscle atrophy is facilitated by the modulation of the Akt/mTOR anabolic signaling pathway.

Published
2008

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