Search

Latinx populations have unique barriers to HPV vaccination. In the current study, we assessed the effectiveness of an online intervention to increase HPV vaccination intentions among patients of clinics that principally serve a Latinx population (n = 85%) as part of a randomized control trial (RCT). Participants viewed on an iPad either an individually tailored educational website (CHiCOS) or untailored information derived from the Vaccine Information Sheet (VIS) for HPV. Vaccination intention and related covariates were assessed via survey items administered before (pre-test) and after (post-test) viewing the material. No statistically significant differences were seen in changes of intention to vaccinate between groups (N = 1294). However, 16% of all (tailored and untailored combined) participants increased in their intention to vaccinate, while 7% decreased in intention. Overall 72% of participants had high intentions to vaccinate, yet far fewer actually received a vaccine dose. The current study explores implications of the demonstrated intention-behavior gap. As such, it presents opportunities to improve future interventions-specifically those that employ tailored messaging., Author(s): Jenna E. Reno [sup.1] , Carter Sevick [sup.2] , Julie Maertens [sup.2] , Amanda F. Dempsey [sup.2] Author Affiliations: (1) grid.62562.35, 0000000100301493, RTI International, , Research Triangle Park, NC, [...]

* Context.--The limitations of newer cervical screening tests are still being studied. Objective.--To investigate those limitations, we conducted a retrospective review of 287 cases of cervical squamous cell carcinoma (SCC). Design.--A search through 5 years of records identified 287 women with cervical SCC diagnoses. Clinical history, histopathology, and liquid-based cytology (ThinPrep) and Hybrid Capture 2 (HC2) high-risk human papillomavirus (HPV) results were documented. Polymerase chain reaction HPV tests were performed on SCC tissues with prior negative HC2 results. Results.--Of 287 women, 156 (54.4%) had abnormal cytology results, and 75 (26.1%) had abnormal clinical findings triggering tissue diagnoses of SCC. Among 156 patients with abnormal Papanicolaou (Pap) test results, more-seriously abnormal Pap test results were reported in 142 women (91.1%). Among 31 women with Pap and HC2 HPV cotesting within 1 year of SCC diagnoses, 28 (90%) were [Pap.sup.+]/[HPV.sup.+], 2 (15.5%) were [Pap.sup.+]/[HPV.sup.-], and 1 (3%) was [Pap.sup.-]/[HPV.sup.-]. Two of 3 women with negative HC2 results before SCC diagnosis had abnormal Pap results; 1 had negative Pap reports with questionable lesional cells mimicking atrophy. In all 3 cases of SCC with negative HC2 results, HPV-18 was detected; in 2 cases (66%), HPV-16 was also detected. Conclusions.--Although abnormal cytology preceded most SCC diagnoses, about one-third of patients were referred for diagnostic testing because of clinical suspicion alone. Among 31 SCC cases with liquid-based cytology and high-risk HPV cotest results less than 1 year before SCC diagnoses, 2 patients (6.5%) had [Pap.sup.+]/[HPV.sup.-] results, and 1 patient (3.2%) had [Pap.sup.-]/[HPV.sup.-] results. Polymerase chain reaction detected high-risk HPV DNA in tumor tissues of 3 SCC cases with recent [HC2.sup.-] results. (Arch Pathol Lab Med. 2012; 136:1533-1540; doi: 10.5858/arpa.2011-0609-OA), The Papanicolaou (Pap) test is widely regarded as the most cost-effective cancer screening test in medical history; however, nowhere has screening succeeded in completely eradicating cervical cancer in screened women. [...]