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11 results on '"Sean M Ward"'

1. Molecular markers expressed in cultured and freshly isolated interstitial cells of Cajal

Author

EPPERSON, ANNE, HATTON, WILLIAM J., CALLAGHAN, BRID, DOHERTY, PHILIP, WALKER, REBECCA L., SANDERS, KENTON M., WARD, SEAN M., and HOROWITZ, BURTON

Subjects
Gastrointestinal system -- Research, Smooth muscle -- Research, Biological sciences
Abstract

Epperson, Anne, William J. Hatton, Brid Callaghan, Philip Doherty, Rebecca L. Walker, Kenton M. Sanders, Sean M. Ward, and Burton Horowitz. Molecular markers expressed in cultured and freshly isolated interstitial cells of Cajal. Am J Physiol Cell Physiol 279: C529-C539, 2000.--Located within the tunica muscularis of the gastro-intestinal (GI) tract are networks of cells known as interstitial cells of Cajal (ICC). ICC are critical for important basic functions of GI motility such as generation and propagation of slow-wave pacemaker activity and reception of regulatory inputs from the enteric nervous system. We have developed a novel procedure to identify and isolate individual ICC from freshly dispersed cell preparations of the murine small intestine and gastric fundus and to determine differential transcriptional expression We have compared the expression profiles of pacemaker ICC isolated from the murine small intestine (IC-MY) and ICC involved in neurotransmission from the gastric fundus (IC-IM). We have also compared expression profiles between ICC and smooth muscle cells (SMC) and between freshly isolated ICC and cultured ICC. Cultured ICC express smooth muscle myosin, whereas freshly dispersed ICC do not. All cell types express muscarinic receptor types [M.sub.2] and [M.sdub.3], neurokinin receptors [NK.sub.1] and [NK.sub.3], and inhibitory receptor VIP-1, whereas only cultured ICC and SMC express VIP-2. Both cultured and freshly dispersed IC-IM and IC-MY express the soluble form of stem cell factor, whereas SMC from the gastric fundus express only the membrane-bound form. gastrointestinal; smooth muscle; c-kit; development more...

Published
2000

2. Study Results from University of Nevada Provide New Insights into Obesity, Fitness and Wellness [Cardiac Pdgfr Alpha(+) Interstitial Cells Generate Spontaneous Inward Currents That Contribute To Excitability In the Heart]

Subjects
Prevention, Analysis, Risk factors, Heart diseases -- Risk factors -- Prevention, Platelet-derived growth factor receptors -- Analysis, Heart function tests -- Analysis, Histones -- Analysis, Blood platelets -- Receptors
Abstract

2023 JUN 10 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Investigators publish new report on Obesity, Fitness and Wellness. According to news [...]

Published
2023

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3. New Findings in Hyperglycemia Described from University of California Davis [Akap5 Complex Facilitates Purinergic Modulation of Vascular L-type Ca2+ Channel Ca(V)1.2]

Subjects
University of California, Research, Physical fitness -- Research, Medical research, Hyperglycemia -- Research, Gene expression -- Research
Abstract

2020 DEC 5 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Researchers detail new data in Nutritional and Metabolic Diseases and Conditions - [...]

Published
2020

4. Findings on Biosensors Reported by Investigators at University of Nevada (Calcium Transients In Intramuscular Interstitial Cells of Cajal of the Murine Gastric Fundus and Their Regulation By Neuroeffector Transmission)

Subjects
University of Nevada, Reno -- Reports, Research, Reports, Biosensors -- Reports -- Research, Medical equipment -- Research -- Reports, Physiological apparatus -- Research -- Reports
Abstract

2022 OCT 19 (NewsRx) -- By a News Reporter-Staff News Editor at Biotech Week -- Fresh data on Biosensors are presented in a new report. According to news reporting originating [...]

Published
2022

5. Findings from University of Nevada in Cell Biology Reported (Ca2+ Transients In Icc-my Define the Basis for the Dominance of the Corpus In Gastric Pacemaking)

Subjects
Physiological aspects, Analysis, Properties, Calcium ions -- Properties -- Analysis, Calcium channels -- Properties -- Analysis, Gastrointestinal system -- Physiological aspects, Cells (Biology) -- Physiological aspects, Gene expression -- Analysis, Cells -- Physiological aspects
Abstract

2021 NOV 2 (NewsRx) -- By a News Reporter-Staff News Editor at Life Science Weekly -- Researchers detail new data in Cell Biology. According to news originating from Reno, Nevada, [...]

Published
2021

6. New Science Study Results Reported from University of Nevada (Oviductal Motile Cilia Are Essential for Oocyte Pickup but Dispensable for Sperm and Embryo Transport)

Subjects
United States. National Institutes of Health, University of Nevada, Reno, National Academy of Sciences, Research, Embryonic development -- Research
Abstract

2021 JUL 16 (NewsRx) -- By a News Reporter-Staff News Editor at Science Letter -- New research on Science is the subject of a report. According to news reporting from [...]

Published
2021

7. Report Summarizes Cell and Tissue Research Study Findings from University of Melbourne (The identification of neuronal control pathways supplying effector tissues in the stomach)

Subjects
University of Melbourne -- Reports, Research, Reports, Neurons -- Research -- Reports
Abstract

2020 NOV 16 (NewsRx) -- By a News Reporter-Staff News Editor at Gastroenterology Week -- Current study results on Life Science Research - Cell and Tissue Research have been published. [...]

Published
2020

8. REAL ESTATE TRANSACTIONS

Subjects
General interest, News, opinion and commentary
Abstract

Saturday July 9, 2005 Section CENTRAL TAMPA Page 5 REAL ESTATE TRANSACTIONS The address shown is the mailing address listed by the buyer. ItAEs usually, but not always, the address [...]

Published
2005

9. Nimitz, Air Wing Sailors Gather to Remember Shipmates

Subjects
Business, Business, international
Abstract

M2 PRESSWIRE-1 June 2009-US NAVY: Nimitz, Air Wing Sailors Gather to Remember Shipmates(C)1994-2009 M2 COMMUNICATIONS RDATE:29052009 By Mass Communication Specialist 3rd Class Scott A. McCall, USS Nimitz Public Affairs USS [...] more...

Published
2009

10. Navy Helicopter Crewmembers Identified

Subjects
Business, Business, international
Abstract

M2 PRESSWIRE-22 May 2009-US NAVY: Navy Helicopter Crewmembers Identified(C)1994-2009 M2 COMMUNICATIONS RDATE:21052009 From Commander Naval Air Forces Public Affairs SAN DIEGO (NNS) -- The names of the five Helicopter Anti-submarine [...] more...

Published
2009

11. Your monthly Rx for eating, thinking, and living strong

Author

Chen, Joanne

Subjects
Caffeine -- Physiological aspects, Fashion and beauty, Women's issues/gender studies
Abstract

Fertility Foe A cup of joe might perk up your brain, but it actually diminishes muscle activity in your fallopian tubes--making for the sluggish transport of eggs from ovary to [...]

Published
2011