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1. Prodruggability of carbohydrates--oral FimH antagonists

Author

Schonemann, Wojciech, Kleeb, Simon, Datwyler, Philipp, Schwardt, Oliver, and Ernst, Beat

Subjects
Urinary tract infections -- Care and treatment, Antagonists (Biochemistry) -- Health aspects, Bioavailability -- Observations, Chemistry
Abstract

Abstract: The bacterial lectin FimH is a promising therapeutic target for the nonantibiotic prevention and treatment of urinary tract infections. In this communication, an ester prodrug approach is described to [...]

Published
2016
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