1. A biosensor that uses ion-channel switches
- Author
-
Cornell, B.A., Braach-Maksvytis, V.L.B., King, L.G., Osman, P.D.J., Raguse, B., Wieczorek, L., and Pace, R.J.
- Subjects
Biosensors -- Research ,Environmental issues ,Science and technology ,Zoology and wildlife conservation - Abstract
There are many different potential applications for a biosensing technique in which the conductance of a population of molecular ion channels is switched by the recognition event. These could include cell typing and the detection of DNA, electrolytes and viruses. The biosensor can operate in plasma, human serum and whole blood, and can be used on electrodes with a wide range of dimensions. Its sensitivity can be boosted by operating it under conditions of low channel density.
- Published
- 1997