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9 results on '"Radhakrishnan, Mahesh"'

1. Diabetes-associated depression: The serotonergic system as a novel multifunctional target

Author

Prabhakar, Visakh, Gupta, Deepali, Kanade, Prateek, and Radhakrishnan, Mahesh

Subjects
Depression (Mood disorder) -- Physiological aspects, Diabetes mellitus -- Physiological aspects, Serotonin -- Health aspects, Health
Abstract

Byline: Visakh. Prabhakar, Deepali. Gupta, Prateek. Kanade, Mahesh. Radhakrishnan Diabetes associated depression is a largely understudied field which nonetheless carries a significant disease burden. The very low therapeutic efficacy of [...]

Published
2015

2. Neuropharmacological evaluation of a novel 5-HT[sub]3 receptor antagonist (6g) on chronic unpredictable mild stress-induced changes in behavioural and brain oxidative stress parameters in mice

Author

Bhatt, Shvetank, Radhakrishnan, Mahesh, Jindal, Ankur, Devadoss, Thangaraj, and Dhar, Arghya

Subjects
Brain -- Physiological aspects, Neurological research, Antagonists (Biochemistry) -- Dosage and administration, Oxidative stress -- Research, Pharmaceutical research, Stress (Psychology) -- Drug therapy, Health
Abstract

Byline: Shvetank. Bhatt, Mahesh. Radhakrishnan, Ankur. Jindal, Thangaraj. Devadoss, Arghya. Dhar Aim: The aim of the study was to evaluate a novel 5 HT [sub]3 receptor antagonist (6g) on chronic [...]

Published
2014

3. Anti-anxiety effect of a novel 5-HT [sub]3 receptor antagonist N-(benzo[d]thiazol-2-yl)-3-ethoxyquinoxalin-2-carboxamide (6k) using battery tests for anxiety in mice

Author

Kurhe, Yeshwant, Radhakrishnan, Mahesh, Thangaraj, Devadoss, and Gupta, Deepali

Subjects
Pharmacology, Experimental, Antagonists (Biochemistry) -- Dosage and administration, Drug interactions -- Research, Anxiety -- Prevention, Health
Abstract

Byline: Yeshwant. Kurhe, Mahesh. Radhakrishnan, Devadoss. Thangaraj, Deepali. Gupta Objective: To investigate the anti-anxiety activity of '6k', a novel 5-hydroxytryptamine type 3 (5-HT [sub]3 ) receptor antagonist in in mice. [...]

Published
2014

5. Ondansetron ameliorates depression associated with obesity in high-fat diet fed experimental mice: An investigation-based on the behavioral, biochemical, and molecular approach

Author

Kurhe, Yeshwant and Mahesh, Radhakrishnan

Subjects
Depression (Mood disorder) -- Prevention, Obesity -- Complications and side effects -- Psychological aspects, High fat diet -- Health aspects, Ondansetron -- Dosage and administration, Health
Abstract

Byline: Yeshwant. Kurhe, Radhakrishnan. Mahesh INTRODUCTION: Obesity is an important risk factor for depression as more than half of the obese population is susceptible for depression at double rate. Our [...]

Published
2017

6. Antidepressant-like effect of novel 5-HT3 receptor antagonist N-n-butyl-3-ethoxyquinoxalin-2-carboxamide (6p): An approach using rodent behavioral antidepressant tests

Author

Bhatt, Shvetank, Mahesh, Radhakrishnan, Devadoss, Thangaraj, and Jindal, Ankur

Subjects
Depression, Mental -- Analysis -- Care and treatment, Health
Abstract

Byline: Shvetank. Bhatt, Radhakrishnan. Mahesh, Thangaraj. Devadoss, Ankur. Jindal Objective: The present study was designed to investigate the antidepressant potential of N-n-butyl-3-ethoxyquinoxalin-2-carboxamide ( 6p ), a novel 5-HT [sub]3 receptor [...]

Published
2013

7. Anxiolytic-like effect of (4-benzylpiperazin-1-yl)(3-methoxyquinoxalin-2-yl)methanone (6g) in experimental mouse models of anxiety

Author

Bhatt, Shvetank, Mahesh, Radhakrishnan, Devadoss, Thangaraj, and Jindal, Ankur

Subjects
Serotonin antagonists -- Dosage and administration -- Testing, Drugs -- Product/Service Evaluations, Anxiety -- Care and treatment -- Drug therapy, Health
Abstract

Byline: Shvetank. Bhatt, Radhakrishnan. Mahesh, Thangaraj. Devadoss, Ankur. Jindal Aim: The present study was designed to investigate the anxiolytic activity of 6g, a novel serotonin type-3 receptor (5-HT [sub]3 ) [...]

Published
2013

8. Antidepressant-like activity of (4-phenylpiperazin-1-yl) (quinoxalin-2-yl) methanone (4a), a novel 5-HT [sub]3 receptor antagonist: An investigation in behaviour-based rodent models of depression

Author

Mahesh, Radhakrishnan, Kumar, Baldev, Jindal, Ankur, Bhatt, Shvetank, Devadoss, Thangaraj, and Pandey, Dilip

Subjects
Depression, Mental -- Physiological aspects -- Drug therapy, Antagonists (Biochemistry) -- Physiological aspects -- Health aspects, Pharmaceutical chemistry -- Research, Health
Abstract

Byline: Radhakrishnan. Mahesh, Baldev. Kumar, Ankur. Jindal, Shvetank. Bhatt, Thangaraj. Devadoss, Dilip. Pandey Aim: The present study was designed to investigate the antidepressant potential of (4-phenylpiperazin-1-yl) (quinoxalin-3-yl) methanone (4a), a [...]

Published
2012

9. Reports from Birla Institute of Technology and Science Add New Study Findings to Research in Chemistry [Design, synthesis and evaluation of 2-(4-(substituted benzoyl)-1,4-diazepan-1-yl)-N-phenylacetamide derivatives as a new class of falcipain-2 ...]

Subjects
Physical fitness -- Reports -- Analysis, Proteases -- Reports -- Analysis, Acetanilides -- Reports -- Analysis, Cysteine, Obesity, Malaria, Anopheles, Plasmodium falciparum, Cystine, Editors, Health
Abstract

2019 NOV 23 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- A new study on chemistry is now available. According to news reporting [...]

Published
2019

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