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BACKGROUND: According to a wide variety of analyses and projections, the potential effects of global climate change on human health are large and diverse. The U.S. National Institutes of Health [...]

I. INTRODUCTION Environmental health science has made tremendous strides since the creation of the Environmental Protection Agency (EPA) in 1970 and even since the original passage of the Toxic Substances [...]

As we work to move the NIEHS forward, it is important that we critically consider how our research can have the greatest impact on public health. In last month's Director's [...]

The biotechnology revolution has opened new opportunities for addressing current inadequacies in decision making regarding environmental health. Strategic investments need to be made (1) to develop high-throughput technologies that could accelerate toxicity testing and generate a mechanistic understanding of toxicity, (2) to incorporate individual susceptibility into risk assessments, and (3) to establish a rational basis for testing and regulatory decision making. New initiatives of the National Institute of Environmental Health Sciences, including the Environmental Genome Project and the Toxicogenomics Center, are discussed. (Am J Public Health. 2001; 91:1964-1967)