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1. Characterization of the gene cluster responsible for cylindrospermopsin biosynthesis

Author

Mihali, Troco Kaan, Kellman, Ralf, Muenchhoff, Julia, Barrow, Kevin D., and Neilan, Brett A.

Subjects
Bacterial toxins -- Research, Cyanobacteria -- Genetic aspects, Cyanobacteria -- Physiological aspects, Genetic regulation -- Research, Neurotoxic agents -- Research, Biological sciences
Abstract

The gene cluster is characterized for the biosynthesis of the cyanobacterial toxin cylindrospermopsin (cyr) in Cylindrospermopsis raciborskii AWT205 and the complete biosynthetic pathway is described. The results have helped in the design of toxic strain-specific probes and also for the study of the regulation and biological role of cylindrospermopsin.

Published
2008

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