Byline: Mike Wright (1), Sue Birley (2), Simon Mosey (3) Abstract: This paper argues that it is important to devote greater attention to the study of entrepreneurship in technology transfer in the light of greater government attention, the growth in the phenomenon, the need to identify how wealth can be created from spin-outs, changes in the cultures of universities and differences with technological entrepreneurship in general. The paper summarizes the contributions made by the papers presented in the special issue in terms of their levels of analysis. At the spin-out level, issues are raised concerning identification of typologies of spin-out firms, the evolution of spin-outs and external resources. At the university level, issues concerning policies, internal resources and processes are discussed. An agenda for further research is elaborated which relates to the need to examine further levels of analysis: the academic entrepreneurs themselves and how they recognize opportunities and shape their ideas to meet the market the nature of internal university environments, processes and resources and the nature of the scientific discipline which may have implications for the process of creation and development of spin-out ventures. Author Affiliation: (1) Center for Management Buy-out Research, Nottingham University Business School, Jubilee Campus, Nottingham, NG8 1BB, England (2) Imperial College, UK (3) University of Nottingham Institute for Enterprise and Innovation, Nottingham University Business School, Jubilee Campus, Nottingham, NG8 1BB, England Article History: Registration Date: 18/10/2004 Article note: Until 2003 at