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The islands of the Azores archipelago emerge from an oceanic plateau built on lithosphere increasing in age with distance from the Mid-Atlantic Ridge from 10 to 45 Ma. Here, we present the first comprehensive major and trace element and Sr-Nd-Pb isotope data from Santa Maria, the easternmost island of the archipelago, along with published data from the other Azores islands situated much closer to the Mid-Atlantic Ridge axis. We can show that the distinctively more variable and more enriched trace element ratios at Santa Maria combined with a relatively small range in Sr-Nd-Pb isotope ratios are the result of low degrees of partial melting of a common Azores mantle plume source underneath thicker lithosphere. This implies that melt extraction processes and melting dynamics may be able to better preserve the trace element mantle source variability underneath thicker lithosphere. These conclusions may apply widely for oceanic melts erupted on relatively thick lithosphere. In addition, lower Ti/Sm and K/La ratios and Si[O.sub.2] contents of Santa Maria lavas imply melting of a carbonated peridotite source. Mixing of variable portions of deep small-degree carbonated peridotite melts and shallow volatile-free garnet peridotite could explain the geochemical variability underneath Santa Maria in agreement with the volatile-rich nature of the Azores mantle source. However, Santa Maria is the Azores island where the C[O.sub.2]-rich nature of the mantle source is more evident, reflecting a combination of a smaller extent of partial melting and the positioning at the edge of the tilted Azores mantle plume. Keywords Ocean Island Basalts * Azores * Lithosphere thickness * Melting dynamics * Carbonated peridotite, Introduction Basalts erupted at Ocean Islands (OIB) display a larger trace element and isotopic variability compared to those erupted along mid-ocean ridges (MOR) (e.g., Dupre and Allegre 1983; Hofmann 1997; [...]