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1. Decrease in interferon gamma production and impairment of T-lymphocyte proliferation in peritoneal fluid of women with endometriosis

Author

Hong-Nerng Ho, Ming-Yih Wu, Kuang-Han Chao, Chin-Der Chen, Shee-Uan Chen, Hsin-Fu Chen, and Yu-Shih Yang

Subjects
Endometriosis -- Physiological aspects, Interferon gamma -- Physiological aspects, Peritoneum -- Physiological aspects, Health
Abstract

Abdominal immune system dysfunction may be responsible for some of the damage found in endometriosis. In endometriosis, blood and pieces of tissue from the inner layer of the uterus become implanted in the fallopian tubes and throughout the abdomen. Researchers measured levels of abdominal proteins involved in the immune response in women with and without endometriosis. Elevated concentrations of interleukin-1-beta, interferon-6, and tumor necrosis factor-alpha but decreased levels of interferon-gamma were found in the abdominal fluid of women with endometriosis.

Published
1996

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