1. Adiponectin concentrations: a genome-wide association study
- Author
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Sun Ha Jee, Jae Woong Sull, Jong-Eun Lee, Chol Shin, Jongkeun Park, Heejin Kimm, Eun-Young Cho, Eun-Soon Shin, Ji Eun Yun, Ji Wan Park, Sang Yeun Kim, Sun Ju Lee, Eun Jung Jee, Inkyung Baik, Kao, Linda, Sungjoo Kim Yoon, Yangsoo Jang, and Beaty, Terri H.
- Subjects
Human genome -- Research ,Insulin resistance -- Genetic aspects ,Koreans -- Genetic aspects ,Obesity -- Genetic aspects ,Obesity -- Demographic aspects ,Single nucleotide polymorphisms -- Analysis ,Biological sciences - Abstract
A genome-wide association study (GWAS) is conducted among a sample of Koreans to identify the gene variants which influence levels of adiponectin, which is associated with obesity and insulin resistance. Results reveal that rs3865188 SNP in CDH13 gene on chromosome 16 is strongly associated with adiponectin, thereby demonstrating that genetic variants in CDH13 influence adiponectin levels in the Korean adults examined.
- Published
- 2010