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692 results on '"ISOENZYMES"'

7. New Data from COMSATS University Islamabad Illuminate Findings in Cancer Research (Synthesis of New Sulphonate Derivatives Containing Adamantane and 4-chlorophenyl Moieties As Nucleotide Pyrophosphatase/phosphodiesterase-1 And-3 Inhibitors)

Subjects
Canada. Natural Sciences and Engineering Research Council, Oncology, Experimental, Isoenzymes, Metastasis, Cancer -- Research, Type 2 diabetes, Osteoarthritis, Physical fitness, Health
Abstract

2024 JAN 20 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Data detailed on Cancer Research have been presented. According to news originating [...]

Published
2024

8. Hua Medicine Announces 2024 Interim Results

Subjects
Company sales and earnings, Health care industry, Company earnings/profit, Empagliflozin, Health care industry -- Company sales and earnings, Pharmaceutical industry -- Company sales and earnings, Isoenzymes
Abstract

HONG KONG, Aug 30, 2024 - (ACN Newswire) - - Dorzagliatin (trade name: HuaTangNing, world's first dual-acting glucokinase activator (GKA), successfully entered China's National Reimbursement Drug List for Basic Medical [...]

Published
2024

9. Global Industrial Enzymes Market Report 2025-2035, with Profiles of 70+ Companies Including Allozymes, Aralez Bio, Biomatter, Carbios, FabricNano, Immobazyme, Protein Evolution, Tiamat Sciences & Zya

Subjects
Feed industry, Isoenzymes, Textile industry, General interest, News, opinion and commentary
Abstract

DUBLIN: RESEARCH AND MARKETS has issued the following news release: The 'Global Industrial Enzymes Market 2025-2035' report has been added to ResearchAndMarkets.com's offering. The industrial enzymes market is a rapidly [...]

Published
2024

10. Global Industrial Enzymes Market Report 2025-2035, with Profiles of 70+ Companies Including Allozymes, Aralez Bio, Biomatter, Carbios, FabricNano, Immobazyme, Protein Evolution, Tiamat Sciences & Zya - ResearchAndMarkets.com

Subjects
Feed industry, Isoenzymes, Textile industry, Business, Business, international
Abstract

DUBLIN -- The 'Global Industrial Enzymes Market 2025-2035' report has been added to ResearchAndMarkets.com's offering. The industrial enzymes market is a rapidly growing sector within the biotechnology industry, driven by [...]

Published
2024

11. Global Industrial Enzymes Market Report 2025-2035, with Profiles of 70+ Companies Including Allozymes, Aralez Bio, Biomatter, Carbios, FabricNano, Immobazyme, Protein Evolution, Tiamat Sciences & Zya

Subjects
Isoenzymes, Textile industry, Business, Business, international
Abstract

M2 PRESSWIRE-August 20, 2024-: Global Industrial Enzymes Market Report 2025-2035, with Profiles of 70+ Companies Including Allozymes, Aralez Bio, Biomatter, Carbios, FabricNano, Immobazyme, Protein Evolution, Tiamat Sciences & Zya (C)1994-2024 [...]

Published
2024

13. Global Industrial Enzymes Market Report 2025-2035, with Profiles of 70+ Companies Including Allozymes, Aralez Bio, Biomatter, Carbios, FabricNano, Immobazyme, Protein Evolution, Tiamat Sciences & Zya - ResearchAndMarkets.com

Subjects
Feed industry, Isoenzymes, Textile industry, Biotechnology industry, Pharmaceuticals and cosmetics industries
Abstract

2024 SEP 11 (NewsRx) -- By a News Reporter-Staff News Editor at Biotech Week -- The 'Global Industrial Enzymes Market 2025-2035' report has been added to ResearchAndMarkets.com's offering. The industrial [...]

Published
2024

15. Hua Medicine Announces 2024 Interim Results

Subjects
Bayer AG, Isoenzymes, Work-related injuries, National health insurance, Pharmaceutical industry, Business, Business, international
Abstract

Original Press Release: Aug. 29 -- Hua Medicine issued the following news release: - The world's first innovative dual-function glucokinase activator (GKA) dogliptin (trade name: Huatangning®) was successfully included in [...]

Published
2024

17. Laboratory Reagents: (creatinine Ivd (in Vitro Diagnostics), Reagent); Ivd Total Protein (in Vitro Diagnostics), Reagent; Urea Ivd (in Vitro Diagnostics), Reagent; Alanine Aminotransferase (alt) Ivd (

Subjects
Cholesterol, Isoenzymes, Urea, Medical testing products, Chemical tests and reagents, Low density lipoproteins, Business, international
Abstract

Contract Awarded For Laboratory Reagents: (Creatinine Ivd (In Vitro Diagnostics), Reagent); Ivd Total Protein (In Vitro Diagnostics), Reagent; Urea Ivd (In Vitro Diagnostics), Reagent; Alanine Aminotransferase (Alt) Ivd (In Vitro [...]

Published
2024

18. Disposable Medical Products: Lot #1 Laboratory Reagents

Subjects
Blood -- Medical examination, Diagnostic reagents, Isoenzymes, Diagnostic reagents and test kits, Medical testing products, Business, international
Abstract

Tenders Are Invited For Disposable medical products: Lot #1 Laboratory reagents Disposable medical products: Lot #1 Laboratory reagents: 52925 - Alanine aminotransferase (ALT) IVD (in vitro diagnostics), reagent, DC 021:2015 [...]

Published
2024

20. Different Medicines (laboratory Reagents: 105-000814-00 Alt (4*35 Ml + 2*18 Ml) (code Nk 024:2023 52925 Alanine Aminotransferase (alt) Ivd (in Vitro Diagnostics), Reagent) , 105-000815-00 Ast (4*35 Ml + 2*18 Ml) (code Nk 024:2023 52953 Isoenzymes Of Aspar

Subjects
Diagnostic reagents, Isoenzymes, Diagnostic reagents and test kits, Medical testing products, Business, international
Abstract

Tenders Are Invited For:Different Medicines (Laboratory Reagents: 105-000814-00 Alt (4*35 Ml + 2*18 Ml) (Code Nk 024:2023 52925 Alanine Aminotransferase (Alt) Ivd (In Vitro Diagnostics), Reagent), 105-000815-00 Ast (4*35 Ml [...]

Published
2024

21. Reagents For Biochemical Analyzer Urit_ca 430 According To Dk 021:2015:33690000-3 'miscellaneous Medicinal Products' Code Of Nomenclature Position Dk 021:2015:33696500-0 'laboratory Reagents'

Subjects
Isoenzymes, Chemical tests and reagents, Analytical instruments, Business, international
Abstract

Contract Awarded For Reagents For Biochemical Analyzer Urit_Ca 430 According To Dk 021:2015:33690000-3 'Miscellaneous Medicinal Products' Nomenclature Item Code Dk 021:2015:33696500-0 'Laboratory Reagents' Description Of A Separate Part Or Parts [...]

Published
2024

22. Dk 021:2015 33690000-3 Medicines, Various Reagents For The Clinical Diagnostic Laboratory (nc 024: 2023 52925 Alanine Aminotransferase (alt) Ivd (in Vitro Diagnostics), Reagent, 52953 Aspartate Aminotransferase Isoenzymes (ast) Ivd (in Vitro Diagnostics)

Subjects
Diagnostic reagents, Isoenzymes, Drugs, Amino acids, Medical testing products, Diagnostic equipment (Medical), C-reactive protein, Business, international
Abstract

Tenders Are Invited For: 021:2015 33690000-3 Medicines, Various Reagents For The Clinical Diagnostic Laboratory (Nk 024: 2023 52925 Alanine Aminotransferase (Alt) Ivd (Diagnosis In Vitro), Reagent, 52953 Isoenzymes Of Aspartate [...]

Published
2024

24. Laboratory Reagents

Subjects
Isoenzymes, Protein binding, Chemical tests and reagents, Business, international
Abstract

Contract Awarded For Laboratory Reagents Nk 024:2023 Code 44946 Staining According To Romanovsky, Ivd (In Vitro Diagnostics), Set; Code 52924 Alanine Aminotransferase (Alt) Ivd (In Vitro Diagnostics), Set, Spectrophotometric Analysis; [...]

Published
2024

25. Medicines Are Different (laboratory Reagents According To Code Nk - 58237 Buffer Solvent Of Ivd Samples (in Vitro Diagnostics)

Subjects
Diagnostic reagents, Isoenzymes, Diagnostic reagents and test kits, Drugs, Medical testing products, Business, international
Abstract

Tenders Are Invited For: Medicines are different (Laboratory reagents according to Code NK - 58237 Buffer solvent of IVD samples (in vitro diagnostics) Medicines are different (Laboratory reagents according to [...]

Published
2024

27. Dk 021:2015: 33690000-3 - Various Medicines (dk 021:2015: 33696000-5 - Reagents And Contrast Agents) (codes Nc 024:2023: 53231 Total Bilirubin Ivd (in Vitro Diagnostics), Reagent; 53590 Urea (urea) Ivd (in Vitro Diagnostics), Reagent; 53252 Creatini

Subjects
Diagnostic reagents, Isoenzymes, Urea, Medical testing products, Business, international
Abstract

Tenders Are Invited For:Dk 021:2015: 33690000-3 - Various Medicinal Products (Dk 021:2015: 33696000-5 - Reagents And Contrast Agents) (Codes Nc 024:2023: 53231 - Total Bilirubin Ivd (In Vitro Diagnostics), Reagent; [...]

Published
2024

28. Laboratory Reagents For Chemical Analyzer Vs-430 (mindray)

Subjects
Diagnostic reagents, Isoenzymes, Diagnostic reagents and test kits, Medical testing products, Analytical instruments, Business, international
Abstract

Tenders Are Invited For Laboratory reagents for chemical analyzer VS-430 (Mindray) Laboratory reagents for chemical analyzer VS-430 (Mindray), automatic hematology analyzer VS-760(B), semi-automatic coagulation analyzer SF-400 (SUCCEEDER), urine analyzer UA-66, [...]

Published
2024

29. Reagents (43 Names) (24950000-8 - Specialized Chemical Products) (58237 Buffer Solvent Of Ivd Samples (in Vitro Diagnostics), Automatic/semi-automatic Systems)

Subjects
Automated Systems Inc., Isoenzymes, Food processing machinery industry, Medical testing products, Chemical tests and reagents, Business, international
Abstract

Tenders Are Invited For: Reagents (43 Names) (24950000-8 - Specialized Chemical Products) (58237 Buffer Solvent Of Ivd Samples (In Vitro Diagnostics), Automatic/Semi-Automatic Systems), (61165 Reagent For Lysis Of Blood Cells [...]

Published
2024

30. Code Dc 021:2015 33690000-3 Medicines Are Different (code According To Nc 024:2023- 52925- Alanine Aminotransferase (alt) Ivd (diagnosis In Vitro), Reagent; 52953- Isoenzymes Of Aspartate Aminotrans

Subjects
Isoenzymes, Chemical tests and reagents, Business, international
Abstract

Contract Awarded For Code Dc 021:2015 33690000-3 Medicines Are Different (Code According To Nc 024:2023- 52925- Alanine Aminotransferase (Alt) Ivd (Diagnosis In Vitro), Reagent; 52953- Isoenzymes Of Aspartate Aminotransferase (Ast) [...]

Published
2024

35. Impact of double-stranded RNA characteristics on the activation of human 2'--5'-oligoadenylate synthetase 2 (OAS2)

Author

Koul, Amit, Deo, Soumya, Booy, Evan P., Orriss, George L., Genung, Matthew, and McKenna, Sean A.

Subjects
Biological response modifiers, Aspartate, Interferon, Ligases, Enzyme kinetics, Isoenzymes, RNA, Amino acids, Proteins, Characterization, Enzymes, Biological sciences, University of Manitoba
Abstract

Human 2'--5' oligoadenylate synthetases (OAS) are a family of interferon-inducible proteins that, upon activation by double-stranded RNA, polymerize ATP into 2'--5' linked oligoadenylates. In this study, we probed the RNA cofactor specificity of the two smallest isozymes, OAS1 and OAS2. First, we developed a strategy for the expression and purification of recombinant human OAS2 from eukaryotic cells and quantified the activity of the enzyme relative to OAS1 in vitro. We then confirmed that both OAS2 domains, as opposed to only the domain containing the canonical catalytic aspartic acid triad, are required for enzymatic activity. Enzyme kinetics of both OAS1 and OAS2 in the presence of a variety of RNA binding partners enabled characterization of the maximum reaction velocity and apparent RNA-protein affinity of activating RNAs. While in this study OAS1 can be catalytically activated by dsRNA of any length greater than 19 bp, OAS2 showed a marked increase in activity with increasing dsRNA length with a minimum requirement of 35 bp. Interestingly, activation of OAS2 was also more efficient when the dsRNA contained 3'-overhangs, despite no significant impact on binding affinity. Highly structured viral RNAs that are established OAS1 activators were not able to activate OAS2 enzymatic activity based on the lack of extended stretches of dsRNA of greater than 35 bp. Together these results may highlight distinct subsets of biological RNAs to which different human OAS isozymes respond. Key words: oligoadenylate synthetase, oligoadenylate, viral RNA, RNA. Les 2'--5' oligoadenylate synthases (OAS) humaines forment une famille de proteines inductibles par l'interferon qui, a la suite d'une activation par de l'ARN double-brin, polymerisent l'ATP en oligoadenylates lies en 2'--5'. Dans cette etude, les auteurs ont sonde laspecificite pour l'ARN cofacteur des deux plus petites isozymes, OAS1et OAS2. Ils ont d'abord developpe une strategie permettant d'exprimer et de purifier l'OAS2 recombinante humaine a partir de cellules eucaryotes, et quantifie l'activite de l'enzyme par rapport a l'OAS1 in vitro. Ils ont ensuite confirme que les deux domaines d'OAS2, contrairement au domaine comportant la triade canonique d'acides aspartiques catalytiques seulement, sont requis a l'activite enzymatique. La cinetique enzymatique d'OAS1 et OAS2 en presence d'une variete d'ARN partenaires de liaison a permis de caracteriser la velocite maximale de la reaction et l'affinite apparente ARN-proteine d'ARN activateurs. Alors que dans cette etude, l'OAS1 peut etre activee catalytiquement par un ARN db de n'importe quelle longueur superieure a 19 pb, l'OAS2 montrait un accroissement marque de son activite en fonction de la longueur de l'ARN db, avec une longueur requise minimale de 35 pb. Il est interessant de noter que l'activation d'OAS2 etait aussi plus efficace lorsque l'ARN db comportait des extremites saillantes en 3' malgre l'absence d'impact significatif sur l'affinite de liaison. Les ARN viraux hautement structures qui sont etablis en tant qu'activateurs de l'OAS1 etaient incapables d'activer l'OAS2 sur la base de l'absence de segments etendus d'ARN plus longs que 35 pb. Dans l'ensemble, ces resultats pourront mettre en evidence des sous-categories distinctes d'ARN auxquelles les differentes isozymes d'OAS repondent. [Traduit par la Redaction] Mots-cles : oligoadenylate synthase, oligoadenylate, ARN viral, ARN., Introduction 2'--5'-Oligoadenylate synthetases (OAS) are a family of interferoninducible enzymes that act as pattern recognition receptors (PRR) to bind double-stranded RNA (dsRNA) during viral infection (Hovanessian 2007). Upon interaction with [...]

Published
2020
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36. Data on Phosphotransferases (Alcohol Group Acceptor) Described by Researchers at Wuhan Institute of Technology (Glucokinase as an emerging anti-diabetes target and recent progress in the development of its agonists)

Subjects
Medical research, Medicine, Experimental, Isoenzymes, Diabetes therapy, Phosphotransferases, Blood sugar, Type 2 diabetes, Physical fitness, Health
Abstract

2022 DEC 17 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- A new study on phosphotransferases (alcohol group acceptor) is now available. According [...]

Published
2022

37. Hebrew University of Jerusalem Researchers Target Ovarian Cancer (Exosome Secretion and Epithelial-Mesenchymal Transition in Ovarian Cancer Are Regulated by Phospholipase D)

Subjects
Oncology, Experimental, Women -- Health aspects, Isoenzymes, Stem cells, Cancer -- Development and progression -- Research, Phospholipases, Ovarian cancer -- Development and progression, Health, Women's issues/gender studies, Hebrew University of Jerusalem
Abstract

2022 DEC 1 (NewsRx) -- By a News Reporter-Staff News Editor at Women's Health Weekly -- Fresh data on ovarian cancer are presented in a new report. According to news [...]

Published
2022

38. 53599 Ivd Albumin (in Vitro Diagnostics), Reagent; 53989 Total Ivd Protein (in Vitro Diagnostics), Reagent; 53231 Total Bilirubin Ivd (in Vitro Diagnostics), Reagent; 53236

Subjects
Cholesterol, Diagnostic reagents, Isoenzymes, Aspartate, Medical testing products, Albumin, Business, international
Abstract

Tenders are invited for 53599 ivd albumin (in vitro diagnostics), reagent; 53989 total ivd protein (in vitro diagnostics), reagent; 53231 total bilirubin ivd (in vitro diagnostics), reagent; 53236 conjugated (direct, [...]

Published
2023

39. Provision For Alanine Aminotransferase (alt) Ivd (invitro Diagnostics), Reagent; 52953 Isoenzymes Of Aspartate Aminotransferase (ast) Ivd (invitro Diagnostics), Reagent; 53231 Total Bilirubin Ivd (invitro Diagnostics), Reagent; 53236 Conjugated Direct, Bo

Subjects
Cholesterol, Diagnostic reagents, Isoenzymes, Aspartate, Business, international
Abstract

Tenders are invited for 52925 alanine aminotransferase (alt) ivd (invitro diagnostics), reagent; 52953 isoenzymes of aspartate aminotransferase (ast) ivd (invitro diagnostics), reagent; 53231 total bilirubin ivd (invitro diagnostics), reagent; 53236 [...]

Published
2023

41. Cabergoline: a review of its use in the inhibition of lactation for women living with HIV

Author

Tulloch, Karen J., Dodin, Philippe, Tremblay-Racine, Fannie, Elwood, Chelsea, Money, Deborah, and Boucoiran, Isabelle

Subjects
HIV patients, Cabergoline, Highly active antiretroviral therapy, Bromocriptine, Protease inhibitors, Proteases, HIV, Women, Prolactin, Ethinyl estradiol, Isoenzymes, Breast feeding, Health
Abstract

Introduction: In developed countries, breastfeeding is not recommended for women living with human immunodeficiency virus (WLWH). However, lactation symptoms can be distressing for women who choose not to breastfeed. There is currently no universal guideline on the most appropriate options for prevention or reduction of lactation symptoms amongst WLWH. This review describes the evidence base for using cabergoline, a dopaminergic agonist, for the post-partum inhibition of lactation for WLWH. Methods: A scoping review of post-partum pharmaceutical lactation inhibition specific for WLWH was conducted using searches in PubMed, Medline Ovid, EBM Reviews Ovid, Embase, Web of Science and Scopus until 2019. A narrative review of cabergoline pharmacologic properties, therapeutic efficacy, tolerability data and drug interaction data relevant to lactation inhibition was then conducted. Results and discussion: Among 1366 articles, the scoping review identified 13 relevant publications. Eight guidelines providing guidance regarding lactation inhibition for WLWH and two surveys of medical practice on this topic in UK have been published. Three studies have evaluated the use of pharmaceutical agents in WLWH. Two of these studies evaluated cabergoline and reported it to be an effective method of lactation inhibition in this population. The third study evaluated ethinyl estradiol and bromocriptine use and showed poor efficacy. Cabergoline is a long-acting dopamine D2 agonist and ergot derivative that inhibits prolactin secretion and suppresses physiologic lactation when given as a single oral dose of 1 mg after delivery. Cabergoline is at least as effective as bromocriptine for lactation inhibition with success rates between 78% and 100%. Transient, mild to moderate adverse events to cabergoline are described in clinical trials. Few drug interactions exist as cabergoline is neither a substrate nor an inducer/inhibitor of hepatic cytochrome P450 isoenzymes. There are no reported clinically significant drug-drug interactions between cabergoline and any antiretroviral medications including protease inhibitors. Conclusions: Cabergoline is a safe and effective pharmacologic option for the prevention of physiological lactation and associated physical symptoms in non-breastfeeding women. Future studies should focus on its safety, efficacy and acceptability among WLWH. Keywords: cabergoline; lactation inhibition; lactation suppression; post-partum; HIV, 1 INTRODUCTION HIV is present in breast milk in both cell-free and cell-associated (i.e. intracellular HIV DNA) compartments and transmission of HIV from a mother to her infant has been [...]

Published
2019
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42. Researchers at Davis Heart and Lung Research Institute Publish New Data on Idiopathic Pulmonary Fibrosis (Persistent hypoxia promotes myofibroblast differentiation via GPR-81 and differential regulation of LDH isoenzymes in normal and ...)

Subjects
Isoenzymes, Pulmonary fibrosis, Heart, Health
Abstract

2023 OCT 2 (NewsRx) -- By a News Reporter-Staff News Editor at Respiratory Therapeutics Week -- Data detailed on idiopathic pulmonary fibrosis have been presented. According to news originating from [...]

Published
2023

43. New Horseradish Peroxidase Structured by Polypeptide Chains (33,890 Da)

Subjects
Isoenzymes, Biological products, Peroxidase, Enzyme-linked immunosorbent assay, Business, Computers and office automation industries, High technology industry
Abstract

Available with an isoelectric point of pH 3–9 Consists of isoenzymes with a molecular weight of 44,000 Da Ideal for western blotting, ELISA, and immunohistochemistry ******************** Creative Enzymes, a professional enzyme [...]

Published
2022

45. Researcher at Taif University Targets Phosphotransferases (Alcohol Group Acceptor) (Development of antidiabetic drugs from benzamide derivatives as glucokinase activator: A computational approach)

Subjects
Isoenzymes, Diabetes therapy, Diabetes -- Drug therapy, Phosphotransferases, Hypoglycemic agents, Physical fitness, Health
Abstract

2022 MAY 14 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Investigators publish new report on phosphotransferases (alcohol group acceptor). According to news [...]

Published
2022

47. Relationship of levetiracetam and serum creatine phosphokinase in children with epilepsy

Author

Panda, Prateek and Sharawat, Indar

Subjects
Isoenzymes, Levetiracetam, Creatine kinase, Epilepsy, Creatine, Health
Abstract

Byline: Prateek. Panda, Indar. Sharawat Dear editor, We read with great interest the recently published article titled 'Effect of levetiracetam usage on serum creatine phosphokinase concentration in patients with epilepsy' [...]

Published
2021

49. Provision For Laboratory Reagents That Do Not Belong To Medicinal Products, 47 Names (dk 021:2015 33690000-3 Various Medicinal Products; Nk 024:2023: 59073 Amylase, Ivd Isoenzymes (in Vitro Diagnostics), Set, Enzyme Spectrophotometric Analysis, 52925 Alan

Subjects
Amylases, Isoenzymes, Aspartate, Medical testing products, Chemical tests and reagents, Business, international
Abstract

Tenders are invited for Laboratory reagents that do not belong to medicinal products, 47 names (dk 021:2015 33690000-3 various medicinal products; nk 024:2023: 59073 amylase, ivd isoenzymes (in vitro diagnostics), [...]

Published
2023

50. GenScript to Debut Expanded Synthetic Biology Product Line at SynBioBeta 2023

Subjects
Isoenzymes, DNA synthesis, General interest, News, opinion and commentary
Abstract

PISCATAWAY: GenScript Biotech Corporation has issued the following news release: GenScript Biotech Corporation, the world's leading provider of life-science research tools and services, is a sponsor of this year's SynBioBeta [...]

Published
2023

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