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19 results on '"Hui, David S."'

1. Why did outbreaks of severe acute respiratory syndrome occur in some hospital wards but not in others?

Author

Yu, Ignatius T., Xie, Zhan Hong, Tsoi, Kelvin K., Chiu, Yuk Lan, Lok, Siu Wai, Tang, Xiao Ping, Hui, David S., Lee, Nelson, Li, Yi Min, Huang, Zhi Tong, Liu, Tao, Wong, Tze Wai, Zhong, Nan Shan, and Sung, Joseph J.

Subjects
Severe acute respiratory syndrome -- Development and progression, Epidemiology -- Reports, Cross infection -- Causes of, Cross infection -- Reports, Nosocomial infections -- Causes of, Nosocomial infections -- Reports, Health, Health care industry
Published
2007

2. Short-term outcome of critically ill patients with severe acute respiratory syndrome

Author

Gomersall, Charles D., Joynt, Gavin M., Lam, Philip, Li, Thomas, Yap, Florence, Lam, Doris, Buckley, Thomas A., Sung, Joseph J. Y., Hui, David S., Antonio, Gregory E., Ahuja, Anil T., and Leung, Patricia

Subjects
Acute respiratory distress syndrome -- Patient outcomes, Critically ill -- Prognosis, Health care industry
Abstract

Byline: Charles D. Gomersall (1), Gavin M. Joynt (1), Philip Lam (1), Thomas Li (1), Florence Yap (1), Doris Lam (1), Thomas A. Buckley (1), Joseph J. Y. Sung (2), David S. Hui (2), Gregory E. Antonio (3), Anil T. Ahuja (3), Patricia Leung (1) Keywords: Coronavirus infections; Barotrauma; Critical care; Pneumonia, viral; Morbidity; Mortality Abstract: Objective To document the outcome and determine prognostic factors for patients with severe acute respiratory syndrome who require admission to an intensive care unit. Design Observational cohort study involving retrospective analysis of demographic, clinical, laboratory and radiological data. Setting Adult intensive care unit in a tertiary referral university hospital involved in a major outbreak of severe acute respiratory syndrome (SARS). Patients The first 54 patients admitted with SARS to an intensive care unit (ICU). All were treated with corticosteroids, ribavirin, broad spectrum antimicrobials and supportive therapy. Interventions None. Measurements and results All patients were admitted for respiratory failure. The median APACHE II score was 11 (interquartile range 8--13). At 28 days 34 patients (63% 95% CI 49.6--74.6) were alive and not mechanically ventilated. Six patients were alive but ventilated (11.3% 95% confidence interval 5.3--22.6) and 14 had died (25.9% CI 16.1--38.9). Seven of 27 ventilated patients developed evidence of barotrauma (25.9% 95% CI 13.2--44.7). Median maximal multiple-organ dysfunction score was 5 (interquartile range 3.3--9). Median maximal respiratory dysfunction score was 3 (interquartile range 3--4). Increased age, severity of illness, lymphocyte count, decreased steroid dose, positive fluid balance, chronic disease or immunosuppression and nosocomial sepsis were associated with poor outcome on univariate analysis. Poor outcome was defined as death or need for mechanical ventilation at 28 days after ICU admission. Conclusions Mortality amongst critically ill patients with SARS is high. It causes predominantly severe respiratory failure, with little other organ failure, and a high incidence of barotrauma amongst those requiring mechanical ventilation. Author Affiliation: (1) Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong (2) Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong (3) Department of Diagnostic Radiology and Organ Imaging, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong Article History: Registration Date: 17/12/2003 Received Date: 04/08/2003 Accepted Date: 10/12/2003 Online Date: 23/01/2004 Article note: Electronic Supplementary Material Supplementary material is available in the online version of this article at http://dx.doi.org/10.1007/10.1007/00134-003-2143-y

Published
2004

5. Exhaled air and aerosolized droplet dispersion during application of a jet nebulizer

Author

Hui, David S., Chow, Benny K., Chu, Leo C.Y., Ng, Susanna S., Hall, Stephen D., Gin, Tony, and Chan, Matthew T.V.

Subjects
Emergency management -- Management, Nebulizers and vaporizers -- Usage, Nebulizers and vaporizers -- Health aspects, Medical personnel -- Safety and security measures, Medical personnel -- Health aspects, Lung diseases -- Care and treatment, Lung diseases -- Prevention, Disease transmission -- Prevention, Company business management, Health
Published
2009

6. Exhaled air dispersion during oxygen delivery via a simple oxygen mask

Author

Hui, David S., Hall, Stephen D., Chan, Matthew T.V., Chow, Benny K., Ng, Susanna S., Gin, Tony, and Sung, Joseph J.Y.

Subjects
Oxygen equipment (Medical care) -- Usage, Air quality -- Research, Air quality -- Health aspects, Community-acquired infections -- Research, Bacterial pneumonia -- Research, Pneumonia -- Research, Disease transmission -- Research, Health
Published
2007

7. Prospective comparison of three predictive rules for assessing severity of community-acquired pneumonia in Hong Kong

Author

Man, Shin Yan, Lee, Nelson, Ip, Margaret, Antonio, Gregory E., Chau, Shirley S.L., Mak, Paulina, Graham, Colin A., Zhang, Mingdong, Lui, Grace, Chan, Paul K.S., Ahuja, Anil T., Hui, David S., Sung, Joseph J.Y., and Rainer, Timothy H.

Subjects
Bacterial pneumonia -- Development and progression, Bacterial pneumonia -- Patient outcomes, Bacterial pneumonia -- Research, Pneumonia -- Development and progression, Pneumonia -- Patient outcomes, Pneumonia -- Research, Mortality -- Hong Kong, Mortality -- Research, Health
Published
2007

8. Airflows around oxygen masks: a potential source of infection?

Author

Hui, David S., Ip, Margaret, Tang, Julian W., Wong, Alexandra L.N., Chan, Matthew T.V., Hall, Stephen D., Chan, Paul K.S., and Sung, Joseph J.Y.

Subjects
Airborne infection -- Research, Airborne infection -- Causes of, Bacterial pneumonia -- Research, Bacterial pneumonia -- Physiological aspects, Pneumonia -- Research, Pneumonia -- Physiological aspects, Health
Published
2006

10. The 1-year impact of severe acute respiratory syndrome on pulmonary function, exercise capacity, and quality of life in a Cohort of survivors *

Author

Hui, David S., Wong, Ka T., Ko, Fanny W., Tam, Lai S., Chan, Doris P., Woo, Jean, and Sung, Joseph J.Y.

Subjects
Lung diseases -- Diagnosis, Lung diseases -- Care and treatment, Severe acute respiratory syndrome -- Diagnosis, Severe acute respiratory syndrome -- Care and treatment, Quality of life, Health
Abstract

Objective: To examine pulmonary function, exercise capacity, and health-related quality of life (HRQoL) among severe acute respiratory syndrome (SARS) survivors. Methods: We evaluated survivors with confirmed SARS at the Prince [...]

Published
2005

11. The effects of nasal continuous positive airway pressure on platelet activation in obstructive sleep apnea syndrome *

Author

Hui, David S., Ko, Fanny W., Fok, Joan P., Chan, Michael C., Li, Thomas S., Tomlinson, Brian, and Cheng, Gregory

Subjects
Sleep apnea syndromes -- Research -- Risk factors, Airway obstruction (Medicine) -- Risk factors -- Research, Health, Research, Risk factors
Abstract

Objective: A ease-controlled study to assess the effects of nasal continuous positive airway pressure (CPAP) on platelet activation in patients with obstructive sleep apnea (OSAS) syndrome. Methods: We recruited 65 [...]

Published
2004

12. The spectrum of severe acute respiratory syndrome--associated coronavirus infection

Author

Rainer, Timothy H., Chan, Paul K.S., Ip, Margaret, Lee, Nelson, Hui, David S., Smit, DeVilliers, Wu, Alan, Ahuja, Anil T., Tam, John S., Sung, Joseph J.Y., and Cameron, Peter

Subjects
Coronaviruses -- Research, Severe acute respiratory syndrome -- Care and treatment, Severe acute respiratory syndrome -- Research, Clinical trials, Health
Abstract

Background: Whether subclinical or atypical presentations of severe acute respiratory syndrome (SARS) occur and whether clinical judgment is accurate in detecting SARS are unknown. Objectives: To describe the spectrum of SARS coronavirus infection in a large outbreak and to compare diagnoses based on clinical judgment with the SARS coronavirus test. Design: Secondary analysis of prospectively collected clinical data and archived serum. Setting: A SARS screening clinic of a university hospital in the New Territories of Hong Kong. Patients: 1221 patients attending the clinic between 12 March 2003 and 12 May 2003. Mcasurements: SARS coronavirus serology. Results: 145 of 553 (26%) patients had serologic evidence of SARS coronavirus infection. Of 910 patients who were managed without hospitalization, only 6 had serologic evidence of SARS. Five of the six patients had normal chest radiographs, and four had symptoms such as myalgia, chills, coughing, and feeling feverish. With the SARS coronavirus serologic test as the gold standard, the clinical diagnosis of probable SARS at hospitalization had a sensitivity of 0.96 (95% CI, 0.91 to 0.98) and a specificity of 0.96 (CI, 0.92 to 0.97). Limitations: Follow-up serologic samples were not obtained from almost half of the patients because they declined further testing. Some people living in the community who were infected but who had minor or no symptoms might not have visited the clinic. Conclusions: There is little evidence of widespread subclinical or mild forms of SARS coronavirus infection. Clinical diagnoses during the outbreak were reasonable and resulted in appropriate triaging.

Published
2004

13. Haematological manifestations in patients with severe acute respiratory syndrome: retrospective analysis. (Papers)

Author

Wong, Raymond SM, Wu, Alan, To, KF, Lee, Nelson, Lam, Christopher WK, Wong, CK, Chan, Paul KS, Ng, Margaret HL, Yu, LM, Hui, David S., Tam, John S., Cheng, Gregory, and Sung, Joseph JY

Subjects
Severe acute respiratory syndrome -- Physiological aspects, Health, Physiological aspects
Abstract

Abstract Objectives To evaluate the haematological findings of patients with severe acute respiratory syndrome (SARS). Design Analysis of the demographic, clinical, and laboratory characteristics of patients with SARS. Setting Prince [...]

Published
2003

14. Index patient and SARS outbreak in Hong Kong

Author

Wong, Raymond S.M. and Hui, David S.

Abstract

During the global outbreak of severe acute respiratory syndrome (SARS) in 2003, treatment was empiric. We report the case history of the index patient in a hospital outbreak of SARS [...]

Published
2004

15. Determinants of Continuous Positive Airway Pressure Compliance in a Group of Chinese Patients With Obstructive Sleep Apnea(*)

Author

Hui, David S. C, Choy, Dominic K. L., Li, Thomas S. T., Ko, Fanny W. S., Wong, Kwok K., Chan, Joseph K. W., and Lai, Christopher K. W.

Subjects
Patient compliance -- Evaluation, Positive pressure respiration -- Evaluation, Sleep apnea syndromes -- Care and treatment, Health, Care and treatment, Evaluation
Abstract

Objective: To assess continuous positive airway pressure (CPAP) compliance and factors associated with CPAP compliance among Chinese patients with obstructive sleep apnea (OSA). Design: A prospective study of 112 consecutive [...]

Published
2001

16. Effects of Augmented Continuous Positive Airway Pressure Education and Support on Compliance and Outcome in a Chinese Population(*)

Author

Hui, David S. C., Chan, Joseph K. W., Choy, Dominic K. L., Ko, Fanny W. S., Li, Thomas S. T., Leung, Roland C. C., and Lai, Christopher K. W.

Subjects
Positive pressure respiration -- Evaluation, Sleep apnea syndromes -- Care and treatment, Health, Evaluation, Care and treatment
Abstract

Objectives: To study the effects of augmentation of continuous positive airway pressure (CPAP) education and support on compliance and outcome in patients with obstructive sleep apnea (OSA). Design: A randomized, [...]

Published
2000

17. Prevalence of Snoring and Sleep-Disordered Breathing in a Student Population(*)

Author

Hui, David S. C., Chan, Joseph K. W., Ho, Alice S. S., Choy, Dominic K. L., Lai, Christopher K. W., and Leung, Roland C. C.

Subjects
Snoring -- Demographic aspects -- Health aspects -- Analysis, College students -- Health aspects -- Analysis, Prevalence studies (Epidemiology) -- Analysis -- Health aspects, Sleep apnea syndromes -- Demographic aspects -- Analysis -- Health aspects, Health, Analysis, Demographic aspects, Health aspects
Abstract

Introduction: The prevalence of snoring and sleep-disordered breathing (SDB) in young adults in Southeast Asian countries is unknown. We aim to determine the symptoms and prevalence of SDB in a [...]

Published
1999

19. The long-term impact of Severe Acute Respiratory Syndrome (SARS) on pulmonary function, exercise capacity, and quality of life in a cohort of survivors

Author

Hui, David S., Ko, Fanny W., Chan, Doris P., Fok, Joan P., Chan, Michael C., To, Kin W., and Sung, Joseph J.

Subjects
Severe acute respiratory syndrome -- Health aspects, Lung diseases -- Risk factors, Health
Abstract

PURPOSE: To examine pulmonary function, exercise capacity, and health-related quality of life (HRQoL) among SARS survivors. METHODS: We evaluated survivors with confirmed SARS at the Prince of Wales Hospital, HK, [...]

Published
2005

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