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1. Trabid, a new positive regulator of Wnt-induced transcription with preference for binding and cleaving K63-linked ubiquitin chains

Author

Hoanh Tran, Hamada, Fumihiko, Schwarz-Romond, Thomas, and Bienz, Mariann

Subjects
Ubiquitin-proteasome system -- Research, Drosophila -- Genetic aspects, Drosophila -- Research, Genetic transcription -- Research, Biological sciences
Abstract

The application of Trabid as a new positive regulator of the Wnt-induced transcription and signaling in mammalian and Drosophila cells is discussed. Trabid is shown to exhibit a preference towards the binding and cleaving of the K63-linked ubiquitin chain, which is extremely important during the transcription.

Published
2008

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