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1. Solid-phase synthesis of peptidomimetic inhibitors for the hepatitis C virus NS3 protease

Author

Poupart, Marc-Andre, Cameron, Dale R., Chabot, Catherine, Ghiro, Elise, Goudreau, Nathalie, Goulet, Sylvie, Poirier, Martin, and Tsantrizos, Youla S.

Subjects
Chemistry, Organic -- Research, Enzymes -- Research, Proteases -- Research, Hepatitis C virus -- Causes of, Peptides -- Research, Biological sciences, Chemistry
Abstract

Research has been conducted on NS3 serine protease enzyme of the hepatitis C virus. The identification of the potent and highly selective NS3 protease enzyme inhibitors has been carried out via automated solid-phase synthesis.

Published
2001

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