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Your search keyword '"Connell, John M. C."' showing total 3 results
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3 results on '"Connell, John M. C."'

1. Insulin- and AICA Riboside-Stimulated Glucose Transport in Primary Muscle Cultures from Control and Insulin Resistant Rats

Author

JAMES, DECLAN J., COLLISON, MARY, SALT, IAN P., DOMINICZAK, ANNA F., CONNELL, JOHN M. C., and GOULD, GWYN W.

Subjects
Insulin -- Physiological aspects, Exercise -- Physiological aspects, Glucose metabolism -- Physiological aspects, Diabetes -- Research, Health
Abstract

Insulin and exercise stimulate glucose uptake in skeletal muscle by inducing the translocation of Glut4 to the cell surface. These two physiological agonists appear to utilise different signalling systems to [...]

Published
2000

2. Cd36 and the Molecular Basis of Insulin Resistance in the Stroke-Prone Spontaneously Hypertensive Rat

Author

COLLISON, MARY, GLAZIER, ANNE M., GRAHAM, DELYTH, MORTON, IAN, DOMINICZAK, MAREK H., AITMAN, TIMOTHY J., CONNELL, JOHN M. C., DOMINICZAK, ANNA F., and GOULD, GWYN W.

Subjects
Insulin resistance -- Genetic aspects, Fatty acid metabolism -- Abnormalities, Stroke (Disease) -- Risk factors, Health
Abstract

Defective Cd36 expression is thought to underlie the defective fatty acid metabolism and hypertriglyceridaemia in the spontaneously hypertensive rat (SHR), and has been linked with insulin resistance which is a [...]

Published
2000

3. ACE Genotype Determines the Magnitude of the Response to Acute, but Not Chronic ACE Inhibition in Type 1 Diabetic Subjects

Author

KENNON, BRIAN, PETRIE, JOHN R., FARMER, ROSIE, CLARK, CATHERINE J., UEDA, SHINICHIRO, SMALL, MICHAEL, and CONNELL, JOHN M. C.

Subjects
Diabetic neuropathies -- Genetic aspects, ACE inhibitors -- Health aspects, Health
Abstract

Background: The insertion/deletion (I/D) polymorphism of the ACE gene is associated with diabetic nephropathy. Thus individuals homozygous for the D allele have a shorter time course from the onset of [...]

Published
2000

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