Search

Your search keyword '"Clarke, Michael J"' showing total 9 results
Start Over Author "Clarke, Michael J" Database Gale General OneFile
9 results on '"Clarke, Michael J"'

1. Non-platinum chemotherapeutic metallopharmaceuticals

Author

Clarke, Michael J., Zhu, Fuchun, and Frasca, Dominic R.

Subjects
Inorganic compounds -- Health aspects, Antineoplastic agents -- Research, Transition metal compounds -- Health aspects, Chemistry
Abstract

Researchers continue to investigate chemotherapeutic drugs containing other transition metals besides platinum. These investigational drugs are based on ruthenium, rhodium, titanium, vanadium, and tin.

Published
1999

2. Obtaining data from randomised controlled trials: how much do we need for reliable and informative meta-analyses?

Author

Clarke, Michael J. and Stewart, Lesley A.

Subjects
Meta-analysis -- Methods -- Usage -- Analysis, Medical literature -- Analysis -- Usage -- Methods, Clinical trials -- Usage -- Analysis -- Methods, Health, Analysis, Usage, Methods
Abstract

Many randomised controlled trials compare treatments that will produce only moderate differences in outcome, but these differences can be clinically important. However, they are difficult to assess reliably and require [...]

Published
1994

3. Crimes of the Middle Classes: White-Collar Offenders in the Federal Courts.

Author

Clarke, Michael J.

Subjects
Crimes of the Middle Classes: White-Collar Offenders in the Federal Courts (Book), Books -- Book reviews
Abstract

This is the last in a series of four books deriving from a National Institute of Justice programme grant, the others being K. Mann's Defending White Collar Crime, S. Shapiro's [...]

Published
1993

4. Solid-state changes in ligand-to-metal charge-transfer spectra of [([NH.sub.3]).sub.5][Ru.sub.III](2,4-dihydroxybenzoate) and [([NH.sub.3]).sub.5][Ru.sub.III](xanthine) chromophores

Author

Krogh-Jespersen, Karsten, Stibrany, Robert T., John, Elizabeth, Westbrook, John D., Emge, Thomas J., Clarke, Michael J., Protenza, Joseph A., and Schugar, Harvey J.

Subjects
Charge transfer -- Analysis, Density functionals -- Usage, Ruthenium -- Atomic properties, Ruthenium -- Chemical properties, X-ray crystallography -- Usage, Xanthine -- Chemical properties, Xanthine -- Structure, Chemistry
Published
2008

5. Ovarian ablation in breast cancer, 1896 to 1998: milestones along hierarchy of evidence from case report to Cochrane review

Author

Clarke, Michael J.

Subjects
Ovariectomy -- Health aspects, Estrogen -- Antagonists, Radiotherapy -- Evaluation -- Health aspects, Breast cancer -- Health aspects, Surgery -- Health aspects, Health, Evaluation, Health aspects
Abstract

One of the earliest randomised trials of a treatment for cancer was of ovarian ablation for breast cancer. Apart from surgical removal of the tumour, this is the oldest treatment [...]

Published
1998

6. Terpsichorean movements of pentaammineruthenium on pyrimidine and isocytosine ligands

Author

LaChance-Galang, Kathleen J., Maldonado, Ishael, Gallagher, Louise M., Clarke, Michael J., Jian, Wei, Galang, Roy D., Prock, Alfred, and Chacklos, Jerome

Subjects
Cytosine -- Research, Cytosine -- Chemical properties, Pyrimidines -- Research, Pyrimidines -- Chemical properties, Ruthenium -- Research, Ruthenium -- Chemical properties, Isomerization -- Research, Chemistry
Abstract

Pentaammineruthenium moves on ambidentate nitrogen heterocycles by both rotation and linkage isomerization. These movements can be choreographed by pH and electrochemical potential.

Published
2001

7. From science to practice: meta-analyses using individual patient data are needed

Author

Oxman, Andrew D., Clarke, Michael J., and Stewart, Lesley A.

Subjects
Meta-analysis -- Evaluation, Medical literature -- Usage, Medical research -- Methods
Abstract

The differences in results of meta-analysis using individual patient data and data available from literature should not cause people to discount the merits of meta-analysis, but results should be evaluated carefully. Publication bias should be considered along with the beneficial outcomes that seem too good to be true. Treatments that show promising results are more likely to be published than those showing negative results. Meta-analysis may be more prone to statistical errors when based on small trials.Inflated results of treatments are often reported long before contradictory information. Clinical decisions are best made when based on a whole body of data.

Published
1995

9. Identifying reports of controlled trials in the BMJ and the Lancet

Author

McDonald, Steven J., Lefebvre, Carol, and Clarke, Michael J.

Subjects
Online services -- Research, Information services industry -- Research, Clinical trials -- Identification and classification -- Research, Information services -- Research, Medical publishing -- Research, Health, Cable television/data services, Online services, Information services industry, Identification and classification, Research
Abstract

In 1994 the European Union BIOMED programme awarded, 330 000 £ to a project, coordinated by the UK Cochrane Centre, to identify reports of randomised controlled trials in general health [...]

Published
1996

Catalog

Books, media, physical & digital resources
See catalog results