Search

Your search keyword '"Chikuma, Masahiko"' showing total 2 results
Start Over Author "Chikuma, Masahiko" Database Gale General OneFile
2 results on '"Chikuma, Masahiko"'

1. A novel isomerization on interaction of antitumor-active azole-bridged dinuclear platinum(II) complexes with 9-ethylguanine. Platinum(II) atom migration from N2 to N3 on 1,2,3-triazole

Author

Komeda, Seiji, Lutz, Martin, Spek, Anthony L., Yamanaka, Yasuyuki, Sato, Takaji, Chikuma, Masahiko, and Reedijk, Jan

Subjects
Chemical research -- Analysis, Isomerization -- Physiological aspects, Platinum -- Physiological aspects, Coordination compounds -- Physiological aspects, Guanine -- Physiological aspects, Ethylene -- Physiological aspects, Solution (Chemistry) -- Physiological aspects, Chemistry
Abstract

Research has been conducted on the dinuclear platinum(II) complexes. The reactions of these complexes with 9-ethylguanine have been monitored in aqueous solution via (super)1 NMR spectroscopy and the results are described.

Published
2002

2. New antitumor-active azole-bridged dinuclear platinum(II) complexes: synthesis, characterization, crystal structures, and cytotoxic studies

Author

Komeda, Seiji, Lutz, Martin, Spek, Anthony L., Chikuma, Masahiko, and Reedijk, Jan

Subjects
Platinum compounds -- Structure, Platinum compounds -- Atomic properties, Chemistry, Inorganic -- Research, Molecular structure -- Research, Chemistry
Abstract

The synthesis, characterization and three single-crystal X-ray structures, as well as the cytotoxic study of the three new azole-bridged dinuclear platinum(II) complexes are reported. A cytotoxicity assay of these dinuclear platinum(II) compounds on human tumor cell lines was performed and the implications of each complex is discussed in the context of a structure-activity relationship.

Published
2000

Catalog

Books, media, physical & digital resources
See catalog results