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I. Introduction II. Overview of Nuclear Envelope and Lamina Proteins A. The lamina and the lamin family B. Integral membrane proteins of the INM C. Lamin modifications and lamin filament [...]

Theory without fact is fantasy, but fact without theory is chaos. C. O. Whitman (334) I. INTRODUCTION A. Scope In birds and mammals, the four chambers of the formed heart [...]

Goll, Darrel E., Valery F. Thompson, Hongqi Li, Wei Wei, and Jinyang Cong. The Calpain System. Physiol Rev 83: 731-801, 2003; 10.1152/physrev.00029.2002.--The calpain system originally comprised three molecules: two [Ca.sup.2+]-dependent [...]

North, R. Alan. Molecular Physiology of P2X Receptors. Physiol Rev 82: 1013-1067, 2002; 10.1152/physrev.00015. 2002.-P2X receptors are membrane ion channels that open in response to the binding of extracellular ATP. [...]

I. INTRODUCTION Learning can be defined as the acquisition of information about the environment that produces an alteration in the behavior of an organism. Memory is the storage of that [...]

I. INTRODUCTION A. Definition of Electrogenic [Na.sup.+]-[K.sup.+] Piunping and Historical Background The [Mg.sup.2+] -dependent, [Na.sup.+] and [K.sup.+]-activated ATPase (EC 3.6.1.37; Ref. 165) is the molecular basis of the [Na.sup.+]-[K.sup.+] pump [...]

I. INTRODUCTION Interest in ATP as a molecule was for many years devoted to the concept of the 'high-energy phosphate bond' introduced by Lippman [292]; this despite the fact that [...]

I. INTRODUCTION Thanks to the pioneering work by W. O. Fenn during the 1930s, it was convincingly demonstrated that [K.sup.+] was lost from skeletal muscles during repeated contractions [194]. Frog, [...]

I. INTRODUCTION Phosphoinositide-specific phospholipase C (PLC) isozymes found in eukaryotes comprise a related group of proteins that cleave the polar head group from inositol phospholipids. Under the control of cell [...]

I. BLOOD PRESSURE AS A QUANTITATIVE TRAIT Quantitative traits are those that show continuous variation from low to high values. This natural variation is present in all populations of eukaryotes [...]

I. INTRODUCTION The cloning of the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR) in 1989 (116) heralded a new era in our ability to study the molecular pathophysiology [...]