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Purpose The oxygen reserve index (ORi[TM]) is a parameter used for the noninvasive evaluation of arterial partial pressure of oxygen (PaO.sub.2), specifically in the 100-200 mmHg range. We aimed to report on the impact of indocyanine green (ICG) on the ORi[TM]. Methods In this study, we retrospectively examined patients who underwent neurosurgery between April and July 2019 and assessed the impact of ICG on ORi[TM]. We excluded patients who did not use ICG or who were not examined for ORi[TM]. The dose and timing of ICG administration were determined by a neurosurgeon. The changes in ORi[TM] were measured for up to 30 min. Results We analyzed ten patients and found that the ORi[TM] increased to 1.00 in all of them. The median time for ORi [TM] to rise to 1.00 after ICG administration was 2 min (range 1-4). After rising to 1.00, ORi [TM] decreased and took 27 min to return to the pre-dose value. Conclusion It is important to consider the initial rapid increase and subsequent slow decrease in ORi[TM] when using ICG during surgery., Author(s): Hiroshi Kondo [sup.1], Ryuji Nakamura [sup.2], Ayako Kobatake [sup.1], Yukiko Nao [sup.1], Ken Hashimoto [sup.1], Keio Nakatani [sup.1] Author Affiliations: (1) grid.505831.a, 0000 0004 0623 2857, Department of Anesthesiology, [...]

The available data that describe Chagas disease's spread and impact are poor: they conceal assumptions, extrapolations and, in a few cases, alleged manipulations by government officials eager to minimize the [...]