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In this technologically advanced age, much emphasis is put on collaboration in education at many levels. As a result, faculty co-teaching (collaborative teaching) has grown dramatically. This paper introduces how two instructors from different countries (USA and Turkey), one experienced in online teaching and the other in medical informatics, collaborated successfully, to develop and teach an online medical informatics course. This study outlines effective strategies in co-teaching and student satisfaction with the course and includes various instructional techniques for cost effective technology for communicating at a distance. (Contains 3 tables.)