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Due to the COVID-19 epidemic, human civilization and the corporate world confront unfathomable risks to their continued existence on the planet. People all over the world are losing employment or seeing their incomes diminish due to the COVID-19 virus influence. As a result, its influence has a direct effect on the purchasing ability of consumers. When a customer’s purchasing capability is diminished, his desire for items decreases. Again, retailers or suppliers of deteriorative goods face a risk in this uncertain environment, since deteriorative products have a limited shelf life. They should have an appropriate business strategy in this circumstance to maintain their commercial profession. Taking all of these factors into account, an inventory model is created that incorporates the COVID-19 influence on consumers’ demand for perishable commodities with preservation capability. Customers are granted a partial trade credit term to enable them to sell the items on time. The proposed model is very intricate and not amenable to an analytical solution. Two numerical cases are explored and solved to demonstrate the proposed model’s practical usefulness. The eigenvalues of that numerical example are determined to demonstrate that the Hessian matrix is positive definite, i.e., to determine the average cost function’s convexity. Finally, we do a post-optimality study to find out how different inventory characteristics affect the best policies.

Using the molecular dynamics (MD) simulations with ReaxFF potential, two different types of PFPE lubricants (Ztetraol and ZTMD) are prepared on a-C film, and SiO2 particles are adsorbed onto the lubricants at room temperature. From the simulation results, it is observed that the adsorbed SiO2 particles increase the stiffness of PFPE lubricants leading to less airshear displacement. Since Ztetraol has higher mobility with lower viscosity than ZTMD, the adsorbed SiO2 particles penetrate deeper into the Ztetraol lubricants. Accordingly, the effect of SiO2 on the airshear displacement is more obvious to Ztetraol than ZTMD. In addition, the adsorbed SiO2 particles increase the friction force and the amount of lubricant pick-up during the sliding contact with a nanosized a-C tip.

Disorders of sexual differentiation (DSD) are among the challenging problems in the field of endocrinology. When presenting late in an adult the therapeutic as well as diagnostic issues may be different and difficult. Bilateral anorchia is rare. The desire of future parenting is a real challenge when such patients ask for their own biological generations. This case depicts the late presentation of DSD in an anorchid adult and the management issues.

Another major force not letting us succeed in the treatment of diabetes remains right inside the patients home, their family members. Hence, it is important to know the perception of the close family members about this simple and strong tool in diabetes, ′insulin′. The drug is nearing its century, it has not fully being accepted gracefully even in todays electronic savvy society. So, we need to strongly discover the reason for its non-acceptance, while trials are out inventing new drugs. One vital thing that can change this attitude is increasing the understanding of this drug, insulin in depth to close people around the patient, the ′family′. Underestimating family′s perception about disease and treatment for diabetes is detrimental to both diseased and the doctor. This consists of a biopsychosocial model; biological, psychological and social factors. Family forms the most important part of it. The strategies in family therapy include psychodynamic, structural, strategic, and cognitive-behavioral component. Diabetes has and will continue to rise, so will be the treatment options. From the clinicians side its to fix fasting first but from patients its fix family first. Family therapy demonstrates the importance of insulin initiation and maintenance in insulin naive patients, and continuation for others. The specific needs of such patients and their impact on family life are met with family therapy. Who needs family therapy? Benefits of family therapy and a case based approach is covered.