5 results on '"Matthew L Smith"'
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2. Exploring associations between skin, the dermal microbiome, and ultraviolet radiation: advancing possibilities for next-generation sunscreens
- Author
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Matthew L. Smith, Catherine A. O’Neill, Mark R. Dickinson, Bhaven Chavan, and Andrew J. McBain
- Subjects
skin microbiome ,sunscreen ,ultraviolet radiation ,sunlight ,microbial selection ,skincare ,Microbial ecology ,QR100-130 - Abstract
Recent studies have provided strong evidence of a functional link between the microbiota of the skin and overall host health. While sunscreens offer protection against acute and chronic dermatological damage by reflecting, absorbing and scattering ultraviolet radiation, their impact on the skin microbiota is poorly understood. The use of sunscreens may affect the skin microbiota directly or indirectly through mechanisms associated with UV protection, and conversely, the microbiota could mediate or alleviate UV-induced skin damage. Here we consider opportunities for the development of improved sunscreens including formulas that work in tandem with skin commensal microorganisms or which minimise direct effects on the skin microbiota.
- Published
- 2023
- Full Text
- View/download PDF
3. Physical Activity, Sitting Time, and Feelings of Energy and Fatigue During the Early Stages of the COVID-19 Pandemic: Does Grit Make a Difference?
- Author
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Andreas Stamatis, Jessica Adams, Joel Martin, Matthew L. Smith, Italia Milani, Shane V. Caswell, Nelson Cortes, and Ali Boolani
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mental energy ,mental fatigue ,physical energy ,physical fatigue ,positive psychology ,health behavior ,mentoring ,sedentary lifestyle ,self-efficacy ,Special aspects of education ,LC8-6691 ,Public aspects of medicine ,RA1-1270 - Abstract
Grit has been associated with feelings of energy when measured as the opposite end of fatigue. During the COVID-19 pandemic, grit has been linked to positive health-related behaviors, which are known to influence feelings of energy and fatigue. The objective of this study was to identify the association between grit, time spent sitting, physical activity (PA), and feelings of mental and physical energy (ME, PE) and fatigue (MF, PF) during the early stages of the COVID-19 pandemic in the United States. Participants (n = 859) completed surveys once. Using a series of multivariate regression models, we assessed the association between grit, time spent sitting, PA and ME, MF, PE, and PF. When accounting for all factors, performing vigorous PA was associated positively with PE and ME and negatively with PF and MF, whereas sitting was related negatively with PE and ME and positively with PF and MF. Grit was not associated with the four moods. Study findings underscore the need to adopt healthy lifestyle behavior to improve feelings of energy and fatigue in the face of a pandemic. During this ongoing global health crisis, these findings present novel and important evidence with possible immediate applications for health behavior, such as informing already-established health behavior theories to, ultimately, design COVID-19-specific interventions.
- Published
- 2022
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- View/download PDF
4. School-Based Nutrition and Physical Activity Program for Rural Elementary School Students: A Pilot Study
- Author
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Shaakira A. Jones, Gillian Danze, Anna Price, Ashley L. Merianos, and Matthew L. Smith
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elementary school ,healthy eating ,physical activity ,intervention ,short-run incentives ,Special aspects of education ,LC8-6691 ,Public aspects of medicine ,RA1-1270 - Abstract
Children who eat unhealthy diets and engage in limited physical activity are susceptible to adverse health effects, such as obesity. This pilot intervention study examined the immediate impact of a health education program, Get Charmed, which used a short-run incentive program as a strategy for motivating rural elementary school students to learn about physical activity and healthy eating behaviors. We assessed kindergarten through fifth grade students’ knowledge of physical activity, healthy eating, and water consumption, at baseline and immediately following the intervention. Get Charmed is a six-week program geared toward elementary-aged children, with aims to increase participants’ knowledge and awareness around healthier lifestyle behaviors. A pre-post evaluation assessed knowledge about healthy eating, physical activity, and hydration among elementary school-aged children (n = 22) enrolled in grades k-5. Frequencies were calculated for the number of correct responses for each item. A series of Wilcoxon signed rank tests were performed to assess changes in knowledge from baseline to post-test. Average knowledge scores for the 3rd-5th grade students increased from 15.56 (± 1.88) to 16.78 (± 1.20), which was statistically significant (z = -2.41, p = 0.016). Average baseline knowledge for the kindergarten to 2nd grade students increased from 9.54 (± 1.66) to 10.46 (± 0.66). For the kindergarten to 2nd grade students, a statistically significant proportion of participants (six out of 13 participants) increased knowledge (z = -1.98, p = 0.048). Implementing Get Charmed with short-run incentives in rural school-based settings is a practical and economical approach to introducing new foods while increasing rural elementary students’ knowledge in the areas of physical activity, nutrition, and hydration.
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- 2022
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5. Biosurfactants: A Covid-19 Perspective
- Author
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Matthew L. Smith, Stefano Gandolfi, Philippa M. Coshall, and Pattanathu K. S. M. Rahman
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biosurfactants ,Covid-19 ,handwash ,soap ,cleaning products ,drug delivery ,Microbiology ,QR1-502 - Abstract
The recent outbreak in severe acute respiratory syndrome – coronavirus-2 (SARS-CoV-2) has demonstrated the complete inability of nations across the world to cope with the pressures of a global pandemic, especially one in which the only current feasible treatments are those which deal with the symptoms alone and not the viral cause. As the death toll rises, scientists begin to fall toward new avenues of research, with novelty showing itself to be an incredible and so far, underrated resource. In this case, the use of biosurfactants in dealing with this pandemic justifies extensive study with their potential applications being in the prevention of viral spread; dealing with the symptoms that develop after the incubation period; directly targeting viral infected cells and preventing the spread of the virus throughout the host, all in addition to also acting as potential drug delivery systems and cleaning agents. This extensive avenue of biosurfactants owes to the simplicity in their amphiphilic structure which permits them to interact directly with the lipid membrane of the coronavirus, in a way which wouldn't be of significant threat to the host. Although it could possibly interact and affect the virus, it could also affect human internal organs/cells by interacting with lipid membrane, if (biosurfactant is) ingested, and it still needs further studies in human models. The structure of the coronavirus, in this case SARS-CoV-2, is detrimentally dependent on the integrity of its lipid membrane which encloses its vital proteins and RNA. Biosurfactants possess the innate ability to threaten this membrane, a result of their own hydrophobic domains across their amphiphilic structure. With biosurfactants additionally being both natural and sustainable, while also possessing a remarkably low cytotoxicity, it is of no doubt that they are going to be of increasing significance in dealing with the current pandemic.
- Published
- 2020
- Full Text
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