Search

In recent years, the development of electronic chips has focused on achieving high integration and lightweight designs. As a result, pulsating heat pipes (PHPs) have gained widespread use as passive cooling devices due to their exceptional heat transfer capacity. Nevertheless, the erratic pulsations observed in slug flow across multiple channels constitute a significant challenge, hindering the advancement of start-up and heat dissipation capabilities in traditional PHP systems. In this paper, we introduce a flat plate pulsating heat pipe (PHP) featuring adaptive structured channels, denoted as ASCPHP. The aim is to enhance the thermal performance of PHP systems. These adaptive structured channels are specifically engineered to dynamically accommodate volume changes during phase transitions, resulting in the formation of a predictable and controllable two-phase flow. This innovation is pivotal in achieving a breakthrough in the thermal performance of PHPs. We experimentally verified the heat transfer performance of the ASCPHP across a range of heating loads from 10 to 75 W and various orientations spanning 0 to 90 degrees, while maintaining a constant filling ratio (FR) of 40%. In comparison to traditional PHP systems, the ASCPHP design, as proposed in this study, offers the advantage of achieving a lower evaporation temperature and a more uniform temperature distribution across the PHP surface. The thermal resistances are reduced by a maximum of 37.5% when FR is 40%. The experimental results for start-up characteristics, conducted at a heating power of 70 W, demonstrate that the ASCPHP exhibits the quickest start-up response and the lowest start-up temperature among the tested configurations. Furthermore, thanks to the guiding influence of adaptive structured channels on two-phase flow, liquid replenishment in the ASCPHP exhibits minimal dependence on gravity. This means that the ASCPHP can initiate the start-up process promptly, even when placed horizontally.

Technical-tactical skills are key to determining table tennis match performance. Identifying the skills that can increase scoring probability when competing against opponents with different racket handedness is vital. The aim of this study was to investigate the technical-tactical actions that could significantly improve scoring efficiency in SH (same-handedness) matches and OH (opposite-handedness) matches. The statistics of 72 top-level men's singles matches were collected (40 SH matches and 32 OH matches). An independent samples t-test was performed to evaluate the differences in the scoring efficiency of the point-winning shot. The results showed that the following maneuvers were crucial technical-tactical skills to increase scoring probability: (1) during the mutual-restriction phase, executing a forehand short push to forehand during service round and a backhand long push to backhand during receiving round against SH opponents (p

Background: Acute heart failure (AHF) is a severe clinical syndrome characterized as rapid onset or worsening of symptoms of chronic heart failure (CHF). Risk stratification for patients with AHF in the intensive care unit (ICU) may help clinicians to predict the 28-day mortality risk in this subpopulation and further raise the quality of care.Methods: We retrospectively reviewed and analyzed the demographic characteristics and serological indicators of patients with AHF in the Medical Information Mart for Intensive Care III (MIMIC III) (version 1.4) between June 2001 and October 2012 and our medical center between January 2019 and April 2021. The chi-squared test and the Fisher's exact test were used for comparison of qualitative variables among the AHF death group and non-death group. The clinical variables were selected by using the least absolute shrinkage and selection operator (LASSO) regression. A clinical nomogram for predicting the 28-day mortality was constructed based on the multivariate Cox proportional hazard regression analysis and further validated by the internal and external cohorts.Results: Age > 65 years [hazard ratio (HR) = 2.47], the high Sequential Organ Failure Assessment (SOFA) score (≥3 and ≤8, HR = 2.21; ≥9 and ≤20, HR = 3.29), lactic acid (Lac) (>2 mmol/l, HR = 1.40), bicarbonate (HCO3-) (>28 mmol/l, HR = 1.59), blood urea nitrogen (BUN) (>21 mg/dl, HR = 1.75), albumin (0.04 ng/ml, HR = 4.02), and creatine kinase-MB (CK-MB) (>5 ng/ml, HR = 1.64) were the independent risk factors for predicting 28-day mortality of intensive care patients with AHF (p < 0.05). The novel nomogram was developed and validated with a promising C-index of 0.814 (95% CI: 0.754–0.882), 0.820 (95% CI: 0.721–0.897), and 0.828 (95% CI: 0.743–0.917), respectively.Conclusion: This study provides a new insight in early predicting the risk of 28-day mortality in intensive care patients with AHF. The age, the SOFA score, and serum TnT level are the leading three predictors in evaluating the short-term outcome of intensive care patients with AHF. Based on the nomogram, clinicians could better stratify patients with AHF at high risk and make adequate treatment plans.

Background: Sepsis, as one of the severe diseases, is frequently observed in critically ill patients, especially concurrent with diabetes. Whether admission blood glucose is associated with the prognosis, and outcome of septic patients is still debatable.Methods: We retrospectively reviewed and analyzed the demographic characteristics of septic patients in the Medical Information Mart for Intensive Care III (MIMIC III, version 1.4) between June 2001 and October 2012. The Chi-square and Fisher's exact tests were used for the comparison of qualitative variables among septic patients with different glucose levels and the 30-day mortality in septic patients with diabetes or not. Univariate and stepwise multivariate Cox regression analyses were used to determine the risk factors for 30-day mortality. Kaplan-Meier analysis was conducted to reveal the different 30-day survival probabilities in each subgroup.Results: A total of 2,948 septic patients (910 cases with diabetes, 2,038 cases without diabetes) were ultimately included in the study. The 30-day mortality was 32.4% (956/2,948 cases) in the overall population without any difference among diabetic and non-diabetic septic patients (p = 1.000). Admission blood glucose levels 65 years (HR = 1.53, p = 0.001), the Sequential Organ Failure Assessment (SOFA) score >5 (HR = 2.26, p < 0.001), lactic acid >2 mmol/L (Lac, HR = 1.35, p = 0.024), and platelet abnormality (300 k/ul: HR = 1.36, p < 0.001) were the independent risk factors for 30-day mortality in septic patients with diabetes. In non-diabetes population, age >65 years (HR = 1.53, p < 0.001), non-White or non-Black patients (HR = 1.30, p = 0.004), SOFA score >5 (HR = 1.56, p < 0.001), blood glucose 2 mmol/L (HR = 1.60, p < 0.001), Lac (HR = 1.61, p < 0.001), urea nitrogen >21 mg/dl (HR = 1.45, p = 0.001), alanine aminotransferase (ALT, HR = 1.31, p = 0.009), total bilirubin >1.2 mg/dl (HR = 1.20, p = 0.033), and low hemoglobin (HR = 1.34, p = 0.001) were the independent risk factors for 30-day mortality.Conclusions: Our results indicate admission blood glucose, especially in terms of