1. Effects of blood transfusion on exercise capacity in thalassemia major patients.
- Author
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Daniela Benedetto, Carmelo Massimo Rao, Claudia Cefalù, Demetrio Oreste Aguglia, Gaia Cattadori, Domenico Giuseppe D'Ascola, Frank Antonio Benedetto, Piergiuseppe Agostoni, and Susanna Sciomer
- Subjects
Medicine ,Science - Abstract
Anemia has an important role in exercise performance. However, the direct link between rapid changes of hemoglobin and exercise performance is still unknown.To find out more on this topic, we studied 18 beta-thalassemia major patients free of relevant cardiac dysfunction (age 33.5±7.2 years,males = 10). Patients performed a maximal cardiopulmolmonary exercise test (cycloergometer, personalized ramp protocol, breath-by-breath measurements of expired gases) before and the day after blood transfusion (500 cc of red cell concentrates). After blood transfusion, hemoglobin increased from 10.5±0.8 g/dL to 12.1±1.2 (p
- Published
- 2015
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