1. Cross-metathesis reaction of α- and β-vinyl C-glycosides with alkenes
- Author
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Ivan Šnajdr, Kamil Parkan, Filip Hessler, and Martin Kotora
- Subjects
C-glycosides ,catalysis ,carbohydrates ,cross-metathesis ,ruthenium ,Science ,Organic chemistry ,QD241-441 - Abstract
Cross-metathesis of α- and β-vinyl C-deoxyribosides and α-vinyl C-galactoside with various terminal alkenes under different conditions was studied. The cross-metathesis of the former proceeded with good yields of the corresponding products in ClCH2CH2Cl the latter required the presence of CuI in CH2Cl2 to achieve good yields of the products. A simple method for the preparation of α- and β-vinyl C-deoxyribosides was also developed. In addition, feasibility of deprotection and further transformations were briefly explored.
- Published
- 2015
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