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Purpose: This study was to compare the effectiveness of chiropractic manipulation and mulligan mobilization on pain and functionality in health care workers diagnosed with chronic low back pain. Material and Methods: Forty volunteers aged 20-50 years (Mulligan group (MMG) 27.70±6.57, chiropractic group (CMG) 31.15± 8.15) who were diagnosed with chronic low back pain were included in the study. All cases were randomly divided into two groups as CMG (n:20; 11 females, 9 males) and MMG (n:20; 17 females, 3 males). All treatment groups were evaluated with a numerical pain scale, Oswestry questionnaire, and goniometer. Chiropractic manipulation was applied to CMG and mulligan mobilization was applied to MMG twice a week for 4 weeks. No extra application has been made other than these treatments. Results: Evaluation was done before and after treatment. There is no difference between groups in terms of anthropometrics. (p>0.05). In-group analysis results showed significant differences in all evaluation parameters in both groups and showed a positive improvement (p0.05). Conclusion: There was no superiority between chiropractic manipulation and mulligan mobilization techniques in terms of successful results in the treatment of chronic low back pain. The use of both methods according to appropriate conditions is accepted in patients with chronic low back pain.

Objective:The aim of this study is to determine the relationship between cervical and lumbar range of motions, pain and postural problems with the time spent in the occupation in dentists.Methods:A total of 56 dentists (27 males, 29 females), participated in this research as a volunteer (age=29.55±9.5 years). Firstly, the participants were divided into 3 groups according to the working years in their life and the time spent at unit during the day; they were also divided into 2 groups according to the intermittent or uninterrupted working conditions during the day. Cervical and lumbar joint range of motions were measured to determine limitations. The McGill pain scale survey was used to evaluate the pain. Kruskal Wallis and Mann-Whitney U tests with a posthoc Bonferroni test were used for all statistical analyses.Results:It was seen that the cervical and lumbar joint range of motions decreased, and the postural deformities in the spine and knee were observed and the level of pain increased significantly in comparatively to the excess of the time spent in the profession. However, in the analysis according to the time spent at the unit during the day, only the decrease in the range of motion of the regions was determined with the increase of the time spent at the unit during the day.Conclusion:With the increase in the working years in the dentists, it was revealed that the limitation of the range of motion increased and posture disorders and pain were formed. It is thought that all these problems will be caused by working in non-ergonomic environments for a long time. In this respect, it is important to include experts in the field of physiotherapy in the courses given under the name of preventive medicine. As a result, it can be said that the health problems encountered with the increase in time spent in the profession have increased.

Parkinson's disease (PD) has had six genome-wide association studies (GWAS) conducted as well as several gene expression studies. However, only variants in MAPT and SNCA have been consistently replicated. To improve the utility of these approaches, we applied pathway analyses integrating both GWAS and gene expression. The top 5000 SNPs (p