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Objective: This study amied to investigated the perspective of gastrointestinal （GI） health among consumers of all ages, and their demands on related dietary supplements. Methods: Questionnaires were randomly distributed through the Internet, and 148 consumers completed the questionnaire, including infants, children and teenagers （1~18 years old）, adults （19~55 years old）, and older adults （over 55 years old）. The corresponding results were obtained from the data analyzed by SPSS. Results: Common GI issues affecting consumers include constipation, abdominal bloating and pain as well as diarrhea. Nearly half of consumers are very concerned about GI health. Unhealthy lifestyle habits and unhealthy diets are two main causes of GI issues in adults, while infants, children and teenagers are mainly affected by common cold and low-quality diets. It has been commonly assumed by consumers that GI health is related to low immunity, depression and bad breath in adults, and emaciation and malnutrition in children. Consumers generally take dietary supplements to deal with GI discomfort, among which the number of consumers knowing and taking probiotics is the highest, and yet the feedback on its effect has not been very positive. In their views, probiotics predominantly solve problems concerning GI issues. Sudden GI discomfort is the main cause of consumers taking dietary supplements for GI health, while unhealthy diets in adults and poor appetite in children are also important causes. Conclusion: Consumers are widely affected by GI issues, and there is a relatively high awareness among them of dietary supplements for GI, which are also in high demands varying with age. Further targeted dietary supplements for GI are needed to develop.

Objective： The study aimed to explore the effects of composite probiotics on the intestinal regulation. Methods： By constructing mouse model of constipation, intestinal damage and diarrhea, the intestinal ink propulsion, defecation and intestinal mucosal tissue sections in the control group, model group and probiotics-intervention group were evaluated. The diarrhea index and intestinal mucosal damage index were also considered for comprehensively assessment. Results: Compared with the model group, the mid-and high-concentration of composite probiotics could significantly improve the defecation amount and weight, and the small intestinal ink propulsion rate. Moreover, the intestinal mucosal damage score and histopathological damage were apparently reduced in the probiotics-intervention group at mid-and high-concentrations. The intestinal mucosal damage of diarrhea model mice was relieved by the composite probiotics at all tested concentrations. The mid-and high-concentration of the composite probiotics helped reduce constipation, diarrhea, and intestinal mucosal damage, and the higher concentration worked more effectively. Conclusion: The composite probiotics can be used as an alternative for the probiotics market and provide references for the development of probiotics product.