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Introduction. Vascular endothelial growth factor (VEGF), an angiogenic factor secreted by type II pneumocytes, could play a role in congenital diaphragmatic hernia (CDH) pathogenesis. Animal studies suggest that VEGF accelerates lung growth. Aim. To quantify VEGF on fetal lungs in a nitrofen rat model for CDH and to analyze the effect of tracheal occlusion (TO) in VEGF in fetal lung rats after nitrofen and in control rats not exposed to nitrofen. Methods. Pregnant rats received nitrofen on day 9.5 of gestation. Fetuses were divided into 2 groups: those that underwent TO on day 20 and those that did not. On day 21, fetuses were delivered, and the lungs were dissected for subsequent VEGF quantification. Results. CDH was detected in 43% of the fetuses that received nitrofen. Fetuses with CDH showed significantly reduced lung weight/fetal weight ratio and lower VEGF levels than the remainder. A higher VEGF value was observed after TO. Conclusions. VEGF protein was significantly lower in fetuses with CDH. TO induced a significant increase in VEGF compared to the fetuses that did not undergo TO. Although not statistically significant, we observed higher VEGF levels in fetuses with CDH and TO compared to fetuses with CDH and no further intervention.

The response to the special 2019 issue of Studia Gilsoniana on economics was so positive that it led to the creation of the Aquinas School of Leadership School of Economics (ASLSE). This 2021 publication is, therefore, a second special issue of Studia Gilsoniana on the same theme and the second installment of ASLSE’s economic journals. We are delighted to present here further fruits of thought from the maturing Studia Gilsoniana and ASLSE partnership. Economics is held to be a value-free, scientific enterprise, and as such there can be no relationship between economics and religion. Ayn Rand, a well-known novelist-turned-philosopher, took this position in an unapologetic way in her writings, specifically in her novel Atlas Shrugged. The contrary position to what we might call the Randian “strict separation” thesis holds that economics and religion are related, in some way and to some degree, and therefore should be considered in tandem. The papers in this special edition of Studia Gilsoniana set out to show the extent and quality of the relationship between economics and religion from a variety of viewpoints and historical periods.

This edition of Studia Gilsoniana inaugurates submission of articles on economic science based upon pre-modern principles of philosophy/science. Today, many journals address the intersection of economics and philosophy. Their contributors include practicing economists, economic historians, economist-philosophers, philosopher-economists, and economic methodologists. Research in this interdisciplinary field began to appear in the 1970s and later took shape in the 1980s with the appearance of its specialized academic journals. Today, the intersection of economics and philosophy is a vibrant area of inquiry and research. Books and journal pages are replete with references to classical philosophers such as Plato and Aristotle and their contributions to economic science. However, stronger connections need to be made related to the application of economic principles from the past to the present based upon enduring pre-modern principles of science. This is precisely what this inaugural issue celebrates.