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1. Exploring the relationship between condition severity and health-related quality of life in people with haemophilia A across Europe: a multivariable analysis of data from the CHESS II study

Author

Enrico Ferri Grazzi, Charles Hawes, Charlotte Camp, David Hinds, Jamie O’Hara, and Tom Burke

Subjects
Haemophilia A, Patient-reported outcomes, Health-related quality of life, Pain, Annual bleeding rate, Problem joints, Computer applications to medicine. Medical informatics, R858-859.7
Abstract

Abstract Background Haemophilia A (HA; Factor VIII deficiency) is a congenital X-linked bleeding disorder characterized by trauma-related or spontaneous bleeding events, most notably arising within the intraarticular space and resulting in chronic inflammation and degeneration of affected joints. Endogenous clotting factor activity relative to normal levels determines the severity of HA symptoms, as mild (> 5–40%), moderate (1–5%), or severe (

Published
2024
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