8 results on '"Andrea Montanari"'
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2. A Combined Use of Custom-Made Partial Pelvic Replacement and Proximal Femur Megaprosthesis in the Treatment of Severe Bone Loss after Multiple Total Hip Arthroplasty Revisions
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Michele Fiore, Azzurra Paolucci, Renato Zunarelli, Marta Bortoli, Andrea Montanari, Andrea Pace, Lorenzo Di Prinzio, Stefania Claudia Parisi, Roberto De Cristofaro, Massimiliano De Paolis, and Andrea Sambri
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severe bone loss ,revision hip arthroplasty ,custom-made ,megaprosthesis ,silver ,Medicine - Abstract
Hip arthroplasty failures (either septic or aseptic) often require multiple revisions, thus leading to severe bone defects. The most common reconstruction methods do not allow the management of severe defects. For this reason, in recent years, techniques borrowed from surgical oncology have been applied in the field of revision surgery to deal with both acetabular and femoral bone losses. In this article, two cases of severe bone deficiency following multiple hip arthroplasty revisions that were treated with a custom-made hip prosthesis combined with a proximal femur megaprosthesis are presented. Both implants were silver coated. A review of the literature was conducted to analyze similar cases treated with either a custom-made prosthesis or a proximal femur megaprosthesis. At the 2-year follow-up, all prostheses were in site without clinical or radiographic signs of implant loosening. No postoperative complications occurred. At the last follow-up, both patients resumed their daily life activities with an MSTS score of 23 and 21, respectively. The combined approach of a proximal femur megaprosthesis with a custom-made partial pelvic replacement is a solution that allows severe bone deficiency cases to be tackled with good functional results. Additionally, silver coating may help prevent recurrence of infection.
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- 2023
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3. Phosphaturic Mesenchymal Tumors with or without Phosphate Metabolism Derangements
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Andrea Montanari, Maria Giulia Pirini, Ludovica Lotrecchiano, Lorenzo Di Prinzio, and Guido Zavatta
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phosphaturic tumor ,tumor-induced osteomalacia ,FGF-23 ,phosphatonin ,surgery ,orthopedics ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
Phosphaturic mesenchymal tumors (PMT) are rare neoplasms, which can give rise to a multifaceted syndrome, otherwise called tumor-induced osteomalacia (TIO). Localizing these tumors is crucial to obtain a cure for the phosphate metabolism derangement, which is often the main cause leading the patient to seek medical help, because of invalidating physical and neuromuscular symptoms. A proportion of these tumors is completely silent and may grow unnoticed, unless they become large enough to produce pain or discomfort. FGF-23 can be produced by several benign or malignant PMTs. The phosphate metabolism, radiology and histology of these rare tumors must be collectively assessed by a multidisciplinary team aimed at curing the disease locally and improving patients’ quality of life. This narrative review, authored by multiple specialists of a tertiary care hospital center, will describe endocrine, radiological and histological features of these tumors, as well as present surgical and interventional strategies to manage PMTs.
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- 2023
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4. Urban environment influences on stress, autonomic reactivity and circadian rhythm: protocol for an ambulatory study of mental health and sleep
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Andrea Montanari, Limin Wang, Amit Birenboim, and Basile Chaix
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environmental stress ,circadian rhythm ,sleep ,mental health ,wearable sensors ,Public aspects of medicine ,RA1-1270 - Abstract
IntroductionConverging evidence suggests that urban living is associated with an increased likelihood of developing mental health and sleep problems. Although these aspects have been investigated in separate streams of research, stress, autonomic reactivity and circadian misalignment can be hypothesized to play a prominent role in the causal pathways underlining the complex relationship between the urban environment and these two health dimensions. This study aims at quantifying the momentary impact of environmental stressors on increased autonomic reactivity and circadian rhythm, and thereby on mood and anxiety symptoms and sleep quality in the context of everyday urban living.MethodThe present article reports the protocol for a feasibility study that aims at assessing the daily environmental and mobility exposures of 40 participants from the urban area of Jerusalem over 7 days. Every participant will carry a set of wearable sensors while being tracked through space and time with GPS receivers. Skin conductance and heart rate variability will be tracked to monitor participants' stress responses and autonomic reactivity, whereas electroencephalographic signal will be used for sleep quality tracking. Light exposure, actigraphy and skin temperature will be used for ambulatory circadian monitoring. Geographically explicit ecological momentary assessment (GEMA) will be used to assess participants' perception of the environment, mood and anxiety symptoms, sleep quality and vitality. For each outcome variable (sleep quality and mental health), hierarchical mixed models including random effects at the individual level will be used. In a separate analysis, to control for potential unobserved individual-level confounders, a fixed effect at the individual level will be specified for case-crossover analyses (comparing each participant to oneself).ConclusionRecent developments in wearable sensing methods, as employed in our study or with even more advanced methods reviewed in the Discussion, make it possible to gather information on the functioning of neuro-endocrine and circadian systems in a real-world context as a way to investigate the complex interactions between environmental exposures, behavior and health. Our work aims to provide evidence on the health effects of urban stressors and circadian disruptors to inspire potential interventions, municipal policies and urban planning schemes aimed at addressing those factors.
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- 2024
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5. Micro urban spaces and mental well-being: Measuring the exposure to urban landscapes along daily mobility paths and their effects on momentary depressive symptomatology among older population
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Giovanna Fancello, Julie Vallée, Cédric Sueur, Frank J. van Lenthe, Yan Kestens, Andrea Montanari, and Basile Chaix
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Daily mobility ,Mental health ,Depression ,GPS ,Ecological momentary assessment ,Urban environment ,Environmental sciences ,GE1-350 - Abstract
The urban environment plays an important role for the mental health of residents. Researchers mainly focus on residential neighbourhoods as exposure context, leaving aside the effects of non-residential environments. In order to consider the daily experience of urban spaces, a people-based approach focused on mobility paths is needed. Applying this approach, (1) this study investigated whether individuals’ momentary mental well-being is related to the exposure to micro-urban spaces along the daily mobility paths within the two previous hours; (2) it explored whether these associations differ when environmental exposures are defined considering all location points or only outdoor location points; and (3) it examined the associations between the types of activity and mobility and momentary depressive symptomatology. Using a geographically-explicit ecological momentary assessment approach (GEMA), momentary depressive symptomatology of 216 older adults living in the Ile-de-France region was assessed using smartphone surveys, while participants were tracked with a GPS receiver and an accelerometer for seven days. Exposure to multiple elements of the streetscape was computed within a street network buffer of 25 m of each GPS point over the two hours prior to the questionnaire. Mobility and activity type were documented from a GPS-based mobility survey. We estimated Bayesian generalized mixed effect models with random effects at the individual and day levels and took into account time autocorrelation. We also estimated fixed effects. A better momentary mental wellbeing was observed when residents performed leisure activities or were involved in active mobility and when they were exposed to walkable areas (pedestrian dedicated paths, open spaces, parks and green areas), water elements, and commerce, leisure and cultural attractors over the previous two hours. These relationships were stronger when exposures were defined based only on outdoor location points rather than all location points, and when we considered within-individual differences compared to between-individual differences.
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- 2023
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6. Does Surgical Approach Influence Complication Rate of Hip Hemiarthroplasty for Femoral Neck Fractures? A Literature Review and Meta-Analysis
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Matteo Filippini, Marta Bortoli, Andrea Montanari, Andrea Pace, Lorenzo Di Prinzio, Gianluca Lonardo, Stefania Claudia Parisi, Valentina Persiani, Roberto De Cristofaro, Andrea Sambri, Massimiliano De Paolis, and Michele Fiore
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hip hemiarthroplasty ,femoral neck fracture ,postero-lateral approach ,lateral approach ,antero-lateral approach ,anterior approach ,Medicine (General) ,R5-920 - Abstract
Background: Femoral neck fractures are an epidemiologically significant issue with major effects on patients and health care systems, as they account for a large percentage of bone injuries in the elderly. Hip hemiarthroplasty is a common surgical procedure in the treatment of displaced femoral neck fractures. Several surgical approaches may be used to access the hip joint in case of femoral neck fractures, each with its own benefits and potential drawbacks, but none of them has consistently been found to be superior to the others. This article aims to systematically review and compare the different approaches in terms of the complication rate at the last follow-up. Methods: an in-depth search on PubMed/Scopus/Web of Science databases and a cross-referencing search was carried out concerning the articles comparing different approaches in hemiarthroplasty and reporting detailed data. Results: A total of 97,576 hips were included: 1030 treated with a direct anterior approach, 4131 with an anterolateral approach, 59,110 with a direct lateral approach, and 33,007 with a posterolateral approach. Comparing the different approaches, significant differences were found in both the overall complication rate and the rate of revision surgery performed (p < 0.05). In particular, the posterolateral approach showed a significantly higher complication rate than the lateral approach (8.4% vs. 3.2%, p < 0.001). Furthermore, the dislocation rate in the posterolateral group was significantly higher than in the other three groups considered (p < 0.026). However, the posterolateral group showed less blood loss than the anterolateral group (p < 0.001), a lower intraoperative fractures rate than the direct anterior group (p < 0.035), and shorter mean operative time than the direct lateral group (p < 0.018). Conclusions: The posterolateral approach showed a higher complication rate than direct lateral approach and a higher prosthetic dislocation rate than the other three types of surgical approaches. On the other hand, patients treated with posterolateral approach showed better outcomes in other parameters considered, such as mean operative time, mean blood loss and intraoperative fractures rate. The knowledge of the limitations of each approach and the most common associated complications can lead to choosing a surgical technique based on the patient’s individual risk.
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- 2023
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7. The Industrial Revolution. Landscapes of a divided nation. Un progetto didattico di ricerca-azione in rete per la scuola secondaria di secondo grado
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Andrea Montanari
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industrial revolution ,landscapes of division ,nuove tecnologie ,WebQuest ,cooperative learning ,inquiry-oriented activity ,ecologia dell’apprendimento ,Education (General) ,L7-991 - Abstract
Among the activities a teacher may adopt in his syllabus, the WebQuest is one of the most effective in creating a good cooperative learning environment based on the constructivist approach. The WebQuest combines inquiry-based authentic material and performance-based tasks that require the use of Internet resources. This article presents a project of English culture for the secondary school developed as a long term WebQuest. After an introduction to the WebQuest learning environment, the article describes step by step the making of the project on the English Industrial Revolution: from the outline and the student group forming, to its final realization and evaluation. A link to read online the five PowerPoints realized by the students is included.
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- 2013
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8. Prigionieri dimenticati. Italiani nei lager della Grande guerra
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Andrea Montanari
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Grande guerra ,Cellelager ,prigionieri ,musica ,teatro ,History of Italy ,DG11-999 - Abstract
L’articolo tratta del ciclo di eventi “Prigionieri dimenticati. Italiani nei lager della Grande guerra”, allestiti a Bibbiano (Reggio Emilia) dal 15 al 29 settembre 2013. La prigionia nel campo di Celle (Germania) è al centro di: una mostra, composta da pannelli esplicativi e oggetti provenienti dai lager e dalle trincee; uno spettacolo teatrale intitolato “Sandrone soldato”, scritto proprio a Celle; e un concerto di musiche originali composte e cantate nei lager e nelle trincee. La Grande guerra, dunque, raccontata in modo del tutto originale.
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- 2013
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