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目的探讨RNA结合基序单链相互作用蛋白3（RBMS3）在上皮性卵巢癌（EOC）组织中的表达，及其与EOC组织的临床病理特征和预后的关系。方法选取蚌埠医学院第一附属医院2015年1月~2019年12月经术后病理证实的110例EOC石蜡包埋组织及73例上皮性卵巢良性肿瘤石蜡包埋组织，利用抗RBMS3的多克隆抗体进行免疫组织化学染色（IHC），检测各组织中RBMS3的表达情况，并分析RBMS3的表达与EOC临床病理参数及预后的相关性。结果在EOC组织与上皮性卵巢良性肿瘤组织中RBMS3均表达，而RBMS3在EOC组织中的表达水平明显低于其在上皮性卵巢良性肿瘤组织中的表达水平（P PPPP

在电信行业中，客户流失的准确预测对于相关企业维持市场竞争力和增加收益至关重要。为此提出一个结合CatBoost算法和SHAP（shapley additive explanations）模型的客户流失预测框架，旨在提高预测的准确性，同时增强模型的可解释性。利用新疆某通信公司的实际营业数据，通过数据预处理及特征工程，构建预测模型，选取5种主要关键性能指标评估模型性能。实验结果显示，所提出模型在选取的评价指标上均优于当前主流机器学习预测模型。最后引入SHAP框架增强模型可解释性，揭示影响客户流失的关键因素，并提供具体的因素影响程度，为电信企业制定针对性的客户保留策略提供了科学依据。

临床上延髓出血是少见的脑出血类型，在文献中多以个案报道形式呈现，而双侧延髓内侧出血更为少见。本文介绍了1例老年男性患者，既往高血压病史多年，平日血压控制不佳，此次以“头晕、头痛伴恶心、呕吐”急性发病，后出现饮水呛咳、吞咽困难、失语、四肢瘫痪等症状。完善头颅CT提示双侧延髓内侧呈“心”形的高密度灶，明确诊断为延髓出血，并考虑此次发病与高血压有关。本文介绍了该患者的诊治经过，并从病因、临床表现、辅助检查、治疗以及结局等方面加以讨论，以期增加临床医师关于此病的诊治经验。 Abstract: In clinical practice, medullary hemorrhage is very rare in intracerebral hemorrhage, and literature often presents it in the form of case reports. Bilateral medial medullary hemorrhage is even rarer. This paper presents a case of an elderly male patient with a long history of hypertension and poorly controlled blood pressure. This time, the patient developed an acute onset of “dizziness, headache accompanied by nausea, vomiting”, and later developed symptoms such as difficulty in swallowing, dysphagia, aphasia, quadriplegia. Cranial CT scan showed a high density area on both sides of the medulla oblongata with a “heart” shape, diagnosed as medullary hemorrhage, and it was considered that this onset is related to hypertension. The full text first introduces the diagnosis and treatment process of the patient, and then discusses the etiology, clinical manifestations, auxiliary examinations, treatment and outcome, aiming to increase clinical experience of clinicians in diagnosis and treatment of this disease.

Arched roof is widely used because of its efficient aerodynamic shape. The rise height (F) of the common arched roof does not change. However, arched roof with variable cross-section gradually appears in the design of various large-scale venues, and there is little research on such roof. Therefore, this paper takes the variable cross-section arched roof as the research object, analyzes the factors that affect the roof through numerical simulation in order to obtaining its wind pressure coefficient (CP) and distribution pattern. The numerical simulation results show that under 3 wind directions of 0°, 45°, and 90°, the windward side of the roof is subjected to severe suction and the CP changes significantly as the rise height to span (F/D) ratio increases. The CP along the roof continues to decreases and the middle of the roof will be subjected to maximum suction when H/D

Objective To investigate the doctor-nurse-linkage mode in the whole process of surgery in the treatment of redundant prepuce and phimosis in children. Methods Totally 120 cases of redundant prepuce and phimosis in children were randomly divided into two groups, with 60 cases in each group. The traditional medical work mode was adopted in the control group, while a doctor-nurse linkage model was used to manage the whole process of surgery. The degree of pain caused by changing dressings and preputial edema were observed. The time of making appointment for surgery, preoperative waiting time and postoperative dressing change waiting time were recorded. The satisfaction of family members, doctors and nurses were evaluated. Results The degree of pain caused by changing dressings was lower in the observation group than that in the control group (P＜0. 05). The incidence of preputial edema in the observation group was lower than that in the control group (P＜0. 05). Patients in the observation group had shorter waiting time for making surgery appointment, surgery and postoperative dressing change than those in the control group(P＜0. 05). The satisfaction of family members, doctors and nurses in the observation group were higher than those in the control group (P＜0. 05). Conclusion The doctor-nurse linkage mode can maximize the core value of professionals, improve work efficiency, reduce the waiting time of patients, and improve the satisfaction of doctors and patients. (目的 探讨医护联动模式在小儿门诊包皮手术全过程管理中的应用效果。方法 120例门诊包皮手术患儿随机分为观察组和对照组, 各60例。对照组采用常规医疗工作模式, 观察组采用医护联动模式进行全程管理。观察2组患儿换药疼痛程度以及包皮水肿情况, 记录2组患儿预约手术排期时间、手术日术前等待时间、术后换药等待时间, 评价患儿家属、医生、护士满意度。结果 观察组换药疼痛程度低于对照组, 差异有统计学意义(P＜0. 05)。观察组术后水肿发生率低于对照组, 差异有统计学意义(P＜0. 05)。观察组预约手术排期时间、手术日术前等待时间、术后换药等待时间均短于对照组, 差异有统计学意义(P＜0. 05)。观察组患儿家属满意度、医生满意度、护士满意度均高于对照组, 差异有统计学意义(P＜0. 05)。结论 医护联动模式有助于发挥专业人员的核心价值, 提高工作效率, 减少患者等待时间, 提高医患满意度。)

考虑具有范数有界不确定性的离散马尔可夫跳跃广义系统的严格耗散性分析和控制问题.首先将严格耗散概念引入到离散马尔可夫跳跃广义系统,利用线性矩阵不等式给出了离散马尔可夫跳跃广义系统鲁棒随机容许且严格耗散的充分条件；然后利用矩阵不等式给出了状态反馈鲁棒严格耗散控制器的存在条件和综合方法.最后通过数值算例说明了所提出方法的有效性.