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Although statistical analysis of our material could indicate that PRV-1 infection is associated with red muscle melanization, other infections or even co-infections with SAV2 or PMCV may have contributed to the development of the condition. All affected samples were positive for PRV-1 with a median I C i SB t sb value of 30.2, for the control fish, four samples were PRV-1 positive, and two were negative. Keywords: filet; melanin; melano-macrophage; piscine myocarditis virus; piscine orthoreovirus 1; salmonid alphavirus EN filet melanin melano-macrophage piscine myocarditis virus piscine orthoreovirus 1 salmonid alphavirus 453 458 6 03/10/23 20230401 NES 230401 INTRODUCTION Farmed Atlantic salmon ( I Salmo salar i L.) are susceptible to melanization of the white muscle ("the filet"), where melanized spots have a prevalence of 20%-30% at slaughter (Mørkøre et al., [16]). Melanized focal changes in skeletal muscle in farmed Atlantic salmon after natural infection with Piscine orthoreovirus (PRV). [Extracted from the article]

In an excavation carried out in 1968 four headdresses dating from the early to first half of the 16th century were discovered in a crypt in the parish church of Lienz in East Tyrol (Austria). All four headdresses are remarkably well preserved and two of them reveal techniques that are surprising considering the early date. A hairnet with macramé knots and a coif adorned with bobbin lace most likely date before 1509 making them the earliest extant examples of macramé and bobbin lace to date. This paper gives an account of the finds and considers the implications these headdresses might have on the history of lace. [ABSTRACT FROM AUTHOR]