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Copyright of Adicciones is the property of Sociedad Cientifica Espanola de Estudios sobre el Alcohol and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Ginecología y Obstetricia de México is the property of Federacion Mexicana de Ginecologia y Obstetricia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Tropical Medicine & International Health is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Objective To describe options for analysing deaths with an unknown cause, which often occur in community-based studies that are used to estimate disease-specific mortality burden and trends in low-income countries. Methods Mathematical formulae were derived that accommodate deaths with an unknown cause for the disease-specific mortality rate, proportion of deaths attributable to the disease and all-cause mortality rate. Seven specific options are presented, including example calculations from a study of childhood malaria mortality in The Gambia. An algorithm is proposed to help make decisions on analysing deaths with an unknown cause. Results In the Gambian study, 25.2% of deaths had an unknown cause. Three options would result in 23.6% (minimum), 48.8% (maximum) and 28.7% (probably the best estimate) of deaths attributed to malaria. The best analysis option depends on the disease of interest: diseases for which the diagnostic method has high sensitivity and specificity (e.g., measles, neonatal tetanus) are best analysed assuming that deaths with an unknown cause never have this cause, while diseases for which specificity and/or sensitivity is low (e.g., malaria) are likely to account for some proportion of deaths with an unknown cause. Conclusions The most important aspects of analysing deaths with unknown cause are choosing appropriate assumptions, describing them explicitly and performing a sensitivity analysis. Studies of causes of death should report several key pieces of information on deaths with unknown cause to aid interpretation. [ABSTRACT FROM AUTHOR]

Copyright of Revista Gerencia y Políticas de Salud is the property of Pontificia Universidad Javeriana and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)