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Copyright of Angewandte Chemie International Edition is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

An operationally simple anhydrous carbene insertion reaction to construct DNA‐encoded libraries (DEL) is reported. The developed reaction employs visible light photolysis of diazo compounds and Reversible Adsorption to Solid Support (RASS) strategy. From readily available amines, alcohols, phenols, and carboxylic acids, a variety of high‐value molecules, including useful unnatural amino acids, ethers, and esters, promising clinical drug derivatives, and bioactive molecules have been constructed. [ABSTRACT FROM AUTHOR]

We show, herein, how the minor ligand modification led to the significant enhancement of both chemical and physical stabilities, as well as the gas sorption property of a Cu(II)-organic framework. Using two analogical bifunctional ligands, two new MOFs, namely {[Cu4Cl(cpt)4]·(NO3)3·4DMF·3H2O}n (1) and {[Cu4(OH)2(tpa)4](NO3)2·2DMA·2H2O}n (2), with similar pore shapes but quite different stabilities were successfully synthesized and fully characterized by performing single crystal X-ray diffraction, powder X-ray diffraction (PXRD), thermogravimetric analysis (TGA) and Fourier transform infrared (FT-IR) spectroscopy. Although both MOFs show similar pore shapes and topical structures, they have quite different stabilities and gas uptake properties. MOF 1 with a single-walled framework is insufficiently robust after the removal of the solvents, while MOF 2 with a double-walled framework could maintain its framework integrality after the activation. Moreover, MOF 2 exhibits excellent moisture-resist properties and can be easily scaled up with good crystal quality and high phase purity. In addition, the CO2 sorption performances of activated MOF 2 were probed both experimentally and computationally. [ABSTRACT FROM AUTHOR]

A Rh(III)‐catalyzed ortho C−H functionalization of N‐nitrosoanilines with α‐sulfonylcarbenes had been developed. The reaction was carried out under mild conditions and the products were obtained with good to excellent yields. The diverse transformations of the products to ortho‐functionalized anilines and nitrogen heterocycles were achieved. Furthermore, a cascade reaction of N‐nitrosoanilines and α‐sulfonyl‐α‐diazo‐ketones provided 3‐sulfonyl‐indoles efficiently. [ABSTRACT FROM AUTHOR]

A subsection interpolation method based on the curve curvature threshold is proposed to resolve the incompatible problem of machining accuracy and machining efficiency in parametric curve machining. In the pre-interpolation stage, the curve curvature threshold is calculated based on geometric and kinematic constraints. The subsection interpolation key points and their nominal velocities are then determined from the curvature threshold points and the start and end points of the curve, and the arc length of each subsegment can be calculated based on the adaptive Simpson method. As a result, the S-type speed planning algorithm and the bidirectional speed scanning algorithm are used to update and realize the global speed curve to reduce the speed fluctuation. In the real-time interpolation stage, the curve interpolation parameters are calculated using the parametric modified second-order Runge–Kutta method, which could improve the interpolation accuracy significantly and also shorten the interpolation time. Finally, it is found using numerical cases that the proposed method can smooth the overall interpolation speed, reduce the speed fluctuation effectively and improve the real-time performance of the interpolation. [ABSTRACT FROM AUTHOR]

Construction of chiral quaternary carbon sterocenters especially spirocycles in complex organic molecules is one of the great synthetic challenges. Using a quinine‐derived squaramide catalyst, the enantioselective Michael addition of 4‐amido‐5‐hydroxypyrazoles to ethylene sulfonyl fluoride (ESF) was developed. This method provides a facile strategy to access a series of structurally diverse pyrazolone derivatives with excellent yields and enantioselectivities. The introduction of quaternary carbon stereocenters and sulfonyl fluoride group leads to the valuable candidates for the drug discovery. Furthermore, the products could be transferred to the spirocyclic derivatives under mild reaction conditions without any loss of the enantioselectivities. [ABSTRACT FROM AUTHOR]

Conjugated porous polymers were successfully synthesized through dynamic covalent condensation polymerization using aromatic anhydrides and triacylhydrazine benzene. The obtained conjugated polymers with unique chemical stability, high specific surface area and electrochemically active carbonyl functional groups exhibited excellent performance as cathode materials for lithium-ion batteries. [ABSTRACT FROM AUTHOR]

The suppression of types I and III interferon (IFN) responses by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) contributes to the pathogenesis of coronavirus disease 2019 (COVID‐19). The strategy used by SARS‐CoV‐2 to evade antiviral immunity needs further investigation. Here, we reported that SARS‐CoV‐2 ORF9b inhibited types I and III IFN production by targeting multiple molecules of innate antiviral signaling pathways. SARS‐CoV‐2 ORF9b impaired the induction of types I and III IFNs by Sendai virus and poly (I:C). SARS‐CoV‐2 ORF9b inhibited the activation of types I and III IFNs induced by the components of cytosolic dsRNA‐sensing pathways of RIG‐I/MDA5‐MAVS signaling, including RIG‐I, MDA‐5, MAVS, TBK1, and IKKε, rather than IRF3‐5D, which is the active form of IRF3. SARS‐CoV‐2 ORF9b also suppressed the induction of types I and III IFNs by TRIF and STING, which are the adaptor protein of the endosome RNA‐sensing pathway of TLR3‐TRIF signaling and the adaptor protein of the cytosolic DNA‐sensing pathway of cGAS–STING signaling, respectively. A mechanistic analysis revealed that the SARS‐CoV‐2 ORF9b protein interacted with RIG‐I, MDA‐5, MAVS, TRIF, STING, and TBK1 and impeded the phosphorylation and nuclear translocation of IRF3. In addition, SARS‐CoV‐2 ORF9b facilitated the replication of the vesicular stomatitis virus. Therefore, the results showed that SARS‐CoV‐2 ORF9b negatively regulates antiviral immunity and thus facilitates viral replication. This study contributes to our understanding of the molecular mechanism through which SARS‐CoV‐2 impairs antiviral immunity and provides an essential clue to the pathogenesis of COVID‐19. [ABSTRACT FROM AUTHOR]

The tertiary amine and ketone components of 1‐carbonyl‐substituted anilines undergo [1,2] and [2,3] Stevens rearrangement reactions, triggered by a C4F9 radical, formed from electron donor–acceptor complexes. This approach enables the formation of a quaternary ammonium salt and thus a Stevens rearrangement to afford indolin‐3‐ones under mild conditions. [ABSTRACT FROM AUTHOR]

This study was to quantitatively investigate the role of morphological and functional parameters of the left atrium (LA) and left atrial appendage (LAA) with 256-slice spiral computed tomography (CT) in the recurrence of atrial fibrillation (AF) after radiofrequency ablation (RFA). Eighty-three patients with AF who underwent RFA for the first time were divided into the recurrence (n = 27) and non-recurrence (n = 56) groups. All patients underwent a 256-slice spiral CT examination before the operation. The clinical data and quantitative measurement of the morphology and functional parameters of the LA and LAA were analyzed, including the maximal and minimal volume, ejection fraction and volume, and volume strain of LAA and LA (LAAVmax, LAAVmin, LAAEF, LAAEV, and LAA-VS, LAVmax, LAVmin, LAEF, LAEV and LA-VS, respectively). The CHA2DS2-VASc score and the proportion of patients with heart failure were significantly (P < 0.05) higher in the recurrence than non-recurrence group. The LAAVmax, LAAVmin, LAVmax, LAVmin, LAAV and LAV were all significantly greater in the recurrence than non-recurrence group (P < 0.05), and the perimeter, major and minor axes of LAA orifice and LAA depth were also significantly greater in the recurrence than non-recurrence group. The LAAEF, LAEF and LAA-VS were significantly (P < 0.05) lower in the recurrence than non-recurrence group (P < 0.05). Heart failure, CHA2DS2-VASC score, LAEF, LAV, LAAEF and LAA-VS were univariately significant (P < 0.05) risk factors for AF recurrence after ablation. Multivariate analysis revealed LAAEF (HR: 0.790, 95% CI: 0.657–0.950, P = 0.012) and LAAV (HR: 1.160, 95% CI: 1.095–1.229, P <0.001) to be two significant independent predictors of recurrence. ROC curve analysis showed that LAAEF <44.68% had the highest predictive value for recurrence after radiofrequency ablation, with the sensitivity of 90% and specificity of 67.4%, whereas LAA volume >9.25 ml had the highest predictive value for AF recurrence after RFA, with the sensitivity of 85.2% and specificity of 67.9%. In conclusion, the volume of left atrium, volume and morphology of left atrial appendage have all significantly increased while the ejection fraction and volume strain of left atrium and left atrial appendage have both significantly decreased in recurrence than in non-recurrence after radiofrequency ablation. The ejection fraction and volume of left atrial appendage are significant independent predictors of atrial fibrillation recurrence after radiofrequency ablation. [ABSTRACT FROM AUTHOR]

A synthetic approach of isoindolinones through intramolecular amidation of ortho‐vinyl benzamides was reported. A variety of N‐aryl isoindolinone derivatives were prepared in moderate to excellent yields using perfluorobutyl iodide as oxidant. [ABSTRACT FROM AUTHOR]

Dietary advanced glycation end products (dAGEs) might be potential toxins involved in the pathogenesis of Alzheimer's disease (AD). Quercetin is a flavonoid possessing neuroprotective effects. We aimed to explore whether a 21 days of dAGEs intake would result in cognitive dysfunction in aged ICR mice, and the protective effects of quercetin, with potential mechanisms explored. Fourteen‐month old ICR mice were randomly assigned into four groups, that is, Control, AGEs, quercetin, and AGE diet supplemented with quercetin. Key markers involved in Aβ, tau, and neuroinflammation from hippocampus and cortex were measured via western blot. Gut microbiota and short chain fatty acids profiles from intestinal contents were measured via 16S rRNA gene sequencing and gas chromatography (GC), respectively. Quercetin alleviated cognitive impairment induced by dAGEs in aged mice. This might be associated with that quercetin reduced cathepsin B, tau phosphorylation, and neuroinflammation, and elevated α‐diversity index (ACE, Chao1, and Shannon index), and reduced phylum Verrucomicrobia of gut microbiota. Practical applications: Alzheimer's disease (AD) has been regarded as the commonest cause of progressive dementia for the elderly. This study is the very first to demonstrate that even a short‐term dietary advanced glycation end product (dAGEs) intake induced impaired cognitive function in aged ICR mice, and querectin is capable of reversing dAGEs‐induced cognitive dysfunction. Reduced tau phosphorylation, neuroinflammation, and altered gut microbiota profiles may be involved in querectin's protective effects against dAGEs‐induced cognitive impairment. Our study suggested that quercetin supplementation might be beneficial for improving cognitive function in elderly subjects with high consumption of dAGEs such as grilling, frying, and broiling of food. [ABSTRACT FROM AUTHOR]

Two polycatenated metal–organic framework materials with different metal centers (Zn2+ for 1 and Cd2+ for 2) were synthesized, which underwent pronounced framework phase transition upon desolvation, and exhibited uncommon temperature-dependent stepwise adsorption and hysteretic desorption of CO2 around room temperature. [ABSTRACT FROM AUTHOR]

A transition metal‐free approach for the generation of radical intermediates via EDA complexes had been developed. This approach enables a cross‐dehydrogenative C−O coupling of oximes with acetonitrile, ketones and esters with high yields and regioselectivities. Perfluorobutyl iodide was used as the unique electron acceptor to trigger a new radical formation. The radical pathway was confirmed by UV‐Vis spectroscopy, radical inhibiting, trapping and kinetics experiments. [ABSTRACT FROM AUTHOR]

A convenient and efficient synthesis of sulfones from sulfinates and aryl halides was developed. The reaction occurred under UV irradiation without transition metal catalyst or photocatalyst. A radical pathway via single‐electron transfer (SET) of electron donor‐acceptor (EDA) complex was proposed based on UV‐vis spectroscopy, radical inhibiting and trapping experiments. [ABSTRACT FROM AUTHOR]

A water-stable EuIII-based metal–organic framework (MOF) with dual-emission luminescence behavior, namely {[Eu4(INO)5(μ3-OH)2Cl4(H2O)]·(NO3)·(H2O)5}n (Eu-MOF; HINO = isonicotinic acid N-oxide), was successfully constructed by the solvothermal reaction of Eu3+ ions with the organic ligand HINO. The cationic 3D framework contains microporous channels with accessible Lewis-base sites and NO3− ions as balanced anions, which all contribute to the selective detection of multifarious analytes. This MOF shows ratiometric detection of acetone, Cr2O72− ions, and nitroaromatic compounds (NACs). In particular, it shows great recognition of four NACs in water, representing the first LnIII-MOF which can display distinguishing fluorescence phenomena on NACs rather than relying on the quenching effect. Furthermore, this is also the first example of a MOF-sensor for detecting these explosives discriminatively by ratiometric methods. Additionally, the mechanisms for luminescent responses towards different analytes have been discussed in detail. [ABSTRACT FROM AUTHOR]

Three LnIII‐based metal‐organic frameworks (MOFs), namely [(Me2NH2)[Ln(OBA)2](Hatz)(H2O)1.5]n [Ln = Dy (1), Er (2), Ho (3); H2OBA = 4, 4'‐oxybis(benzoate) acid, Hatz = 3‐amino‐1,2,4‐triazole], were synthesized with Hatz as the template. In the structure of the three MOFs, the dinuclear LnIII nodes are bridged by four oxygen atoms from syn, syn‐carboxylate groups and this model result in a long distance between Dy–Dy, about 4.143(7) Å. In addition, the terminal carboxylate groups force a sandwich‐like coordination environment. Slow relaxation of the magnetization can be observed for 1, indicative of a single‐molecule magnet (SMM) behavior. Three unusual LnIII‐based metal‐organic frameworks (MOFs) were successfully obtained, in which the dinuclear LnIII nodes are bridged by four oxygen atoms from syn, syn‐carboxylate groups. This model result in a long distance between Ln–Ln. But slow relaxation of the magnetization can be observed, indicative of a single‐molecule magnet (SMM) behavior. [ABSTRACT FROM AUTHOR]

Purpose: To quantitatively investigate left ventricular volume and function in middle-aged healthy subjects.Materials and Methods: Ninety healthy volunteers underwent cardiac 3 Tesla MRI. The left ventricular end-diastolic volume (EDV) and end-systolic volume (ESV), stroke volume (SV), ejection fraction (EF), cardiac output (CO), myocardial mass (MM), and their normalized indices (EDVI, ESVI, SVI, CI, and MI, respectively) after corrected with the body surface area (BSA) were analyzed and compared at different ages.Results: All subjects had successfully completed the 3-Tesla cardiac MR. Females had significantly smaller EDV (110.5 ± 9.2 versus 125.7 ± 8.3 mL), ESV (36.1 ± 3.5 versus 41.5 ± 3.8 mL), SV (74.3 ± 6.3 versus 84.2 ± 6.7 mL), CO (5.4 ± 0.8 versus 5.8 ± 0.9 l/min) and MM (73.0 ± 10.5 versus 94.8 ± 10.6 g) than males (P < 0.05). The EF had no significant (P = 0.47) difference between genders (67.3 ± 1.7 percent in females versus 66.9 ± 2.4 percent in males). After normalization with BSA, no significant (P > 0.05) difference was detected between the genders in EDVI (71.2 ± 4.3 versus 71.1 ± 4.2 mL/m2 , P = 0.882), ESVI (23.3 ± 1.9 versus 23.5 ± 1.9 mL/m2 , P = 0.733) and SVI (47.9 ± 2.9 versus 47.7 ± 3.7 mL/m2 , P = 0.698) except for CI and MI. Females had significantly (P < 0.05) greater CI (3.5 ± 0.4 versus 3.3 ± 0.4) but smaller MI (46.9 ± 5.3 versus 53.6 ± 7.6) than males. EDV, EDVI, ESV, ESVI, SV, and SVI significantly (P < 0.05) decreased with age increase. BSA was positively correlated with EDV, ESV, SV, MM, and CO. No significance (P > 0.05) was detected in other parameters.Conclusion: The left ventricular volume and function differs in women compared with men in the middle-aged population, and these parameters have a tendency of decrease with ageing. J. Magn. Reson. Imaging 2016;44:1143-1150. [ABSTRACT FROM AUTHOR]

Since the discovery of a two-dimensional (2D) electron gas at the LaAlO3/SrTiO3 interface, 2D carrier gases at such oxide interfaces and surfaces have attracted great attention because they can host many important phenomena and may produce novel functional devices. Here, we show through first-principles investigations that the surface 2D electron and hole gases in a KTaO3 (KTO) thin film can be tuned by applying biaxial stress. When increasing compressive in-plane strain, the 2D carrier concentrations decrease down to zero and then a new pair of surface 2D electron and hole gases appears in which the carrier types are switched to the opposite ones. Our analysis indicates that this carrier-type switching occurs because the increasing compressive strain reverses the slope of monolayer-resolved electrostatic potential along the [001] direction. We also present strain-dependent carrier concentrations and effective masses, and explore their thickness dependence. It is further shown that the 2D carrier gases and their strain-driven carrier-type switching across the KTO layer still remain true in the presence of overlayers and epitaxial substrates. These phenomena should be useful to design novel functional devices. [ABSTRACT FROM AUTHOR]

An intramolecular hydroamidation of ortho-vinyl benzamides had been developed. The reaction was promoted efficiently by potassium tert-butoxide and N,N-dimethylformamide without the need for strong oxidants or transition-metal catalysts. A series of dihydroisoquinolinones and 3-benzylisoindolinones were prepared in good to excellent yields. The new method is operationally simple, scalable, and tolerant of various functional groups. [ABSTRACT FROM AUTHOR]

The structural, magnetic, and electronic properties of short-period STO/YTO superlattices consisting of Mott insulator YTiO3 (YTO) and band insulator SrTiO3 (STO) are investigated using the density-functional-theory plus U method. It is found that an insulator–metal transition occurs when a compressive strain is applied, and no transition occurs for tensile strain. Structural analyses reveal that the electronic transition accompanies a structural phase transition, restoring the inversion symmetry, and the strain compresses the interfacial oxygen octahedra of Ti and thus makes the d energy levels of the interfacial Ti atoms move upward so as to induce electron transfer to the STO layer. This mechanism is supported by the fact that a similar insulator–metal transition also occurs when the on-site U is reduced. These findings can improve our understanding of the structural and electronic properties of such oxide superlattices and heterostructures. [ABSTRACT FROM AUTHOR]

Objective The aim of this study was to construct an in vivo carotid siphon model for testing neurovascular devices for endovascular interventions. Methods A model of a human carotid siphon was pre-shaped using a glass tube from a human cadaver and used to confine a segment of one side of the common carotid artery (CCA) in canines. This segment of CCA with the glass carotid siphon on was interposed end-to-end onto the contralateral CCA so as to simulate a human carotid artery siphon in vivo. Two weeks later, the siphon model was evaluated using computed tomography angiography and digital subtraction angiography, and the covered stent specially designed for intracranial vasculature was navigated through the siphon model for a longitudinal flexibility test. Results All dogs tolerated the procedures well, and the artificial siphon model in vivo provided realistic conditions for device testing. Two weeks later, the in vivo carotid siphon model remained patent with no thrombosis. Five covered stents were navigated to pass through five siphon models successfully, with vasospasm occurring in two siphons. Conclusion Construction of an in vivo siphon model in dogs with a glass tube is feasible and useful for the test of endovascular devices for treating neurovascular diseases. [ABSTRACT FROM AUTHOR]

Purpose: To quantitatively measure the morphology parameters of the right auricle with 256-slice multidetector computed tomography angiography (MDCTA) in healthy people. Materials and methods: A retrospective analysis of 200 patients who had undergone coronary MDCTA with negative findings was performed. The raw imaging data were reconstructed and the right auricular volume, right atrial volume, right auricle height, base long and short axes, base perimeter and area, normal angle, and distance were quantitatively measured. Results: Men had significantly ( P < 0.05) greater values than women in the right auricular volume (13.3 ± 4.0 vs. 11.7 ± 3.7 mL) and height (33.0 ± 5.0 vs. 30.5 ± 5.2 mm), the base long axis (34.4 ± 4.1 vs. 33.2 ± 3.9 mm), area (787.6 ± 177.6 vs. 771.0 ± 143.2 mm) and perimeter (119.2 ± 17.5 vs. 115.0 ± 13.0), and the normal distance (22.4 ± 6.6 vs. 20.2 ± 6.7 mm). The normal 95 % reference range for the right auricular parameters was put forward. The right auricular parameters had a good correlation with the right atrium volume, aortic diameter, the body weight, height, and body surface area but a bad correlation with the vertebral body height. Significantly ( P < 0.05) greater values were found in the normal angle and distance in subjects below than over 40 years of age. No other significant ( P > 0.05) difference existed in the other right auricular parameters. Conclusion: Quantitative measurements of the right auricle can help us get a good understanding of the right auricular morphology and its relationship with surrounding structures and are helpful for cardiac interventions of electrophysiology and radiofrequency ablation. [ABSTRACT FROM AUTHOR]

Objectives: To evaluate the classification and diameter of left gastric vein (LGV) in healthy Chinese adults with multi-detector computed tomography (MDCT). Methods: MDCT angiography was performed in 234 healthy adults for the portal venous system. CT cross-sectional thin-layer reconstruction combined with maximum intensity projection, volume rendering and multiplanar reconstruction were applied. The diameter of LGV was measured at the point within 2 cm from LGV origination. Results: Of 234 subjects, 11 subjects (4.70%) who did not have clear images were excluded, and 223 subjects (95.30%) with excellent images were included. The LGV was originated from the portal vein in 46.15%, splenic vein in 30.77%, portal splenic angle in 14.53%, and the left branch of the portal vein in 3.85%. The maximal diameter of LGV was 4.74 ± 0.84 mm with a 95% confidence interval of 4.63-4.85 mm, and the LGV diameter was positively correlated with the weight of patients (R = 0.26, P = 0.006). No significant difference existed in the maximal diameter of LGV at different origination sites (P = 0.35). The diameter of LGV was significantly greater in males than in females (4.90 ± 0.85 vs. 4.56 ± 0.80 mm, P = 0.002), and the maximal diameter of LGV was significantly (P = 0.02) greater in the age range of 30-39 and 40-49 years than in the range of >70 years. No statistical significance (P = 0.36) was detected in the other groups. Conclusion: MDCT can clearly display the detailed anatomy and variation of LGV in healthy adults, providing a normal range of LGV diameter for clinical reference for diagnosing possible portal hypertension and for possible intervention. [ABSTRACT FROM AUTHOR]

A method for the intramolecular addition of triarylmethanes to alkynes has been developed. The reaction was efficiently promoted by KO tBu/DMF without any transition-metal catalyst. A variety of indene derivatives were prepared in moderate to good yields. A cascade cyclization of 2-alkyl-substituted substrates at elevated reaction temperature gave bicyclic indene derivatives. The reaction is proposed to proceed through the generation of a triphenylmethyl radical. [ABSTRACT FROM AUTHOR]

The intramolecular cyclization of allylamines and ketones was achieved in the presence of potassium tert-butoxide and N,N-dimethylformamide. A series of 4-arylquinolines was prepared in good yields. The reaction could be accomplished at room temperature using only a substoichiometric amount of potassium tert-butoxide. On the other hand, the reaction of the structurally analogous allyl ethers afforded diverse products. The reaction may proceed via the rearrangement of α-aminoallyl radicals and the generation of nucleophilic enamine intermediates. This finding represents a new strategy for the synthesis of quinoline derivatives from readily available 2-(allylamino)phenyl ketones. [ABSTRACT FROM AUTHOR]

Objective: To investigate quantitatively the morphology, anatomy and function of the left atrial appendage (LAA) and its relation with adjacent structures. Materials and Methods: A total of 860 patients (533 men, 62.0%, age 55.9±10.4 year) who had cardiac multidetector computed tomography angiography from May to October 2012 were enrolled for analysis. Results: Seven types and 6 subtypes of LAA morphology were found with Type 2 being the most prevalent. Type 5 was more significantly (P<0.05) present in women (8.0%) than in men (4.2%). LAA orifice was oval in 81.5%, triangular in 7.3%, semicircular in 4%, water drop-like in 3.2%, round in 2.4% and foot-like in 1.6%. The LAA orifice had a significantly greater (P<0.01) major axis in men (24.79±3.81) than in women (22.68±4.07). The LAA orifice long axis was significantly (P<0.05) positively correlated with the height, weight and surface area of the patient. The LAA morphology parameters displayed strong positive correlation with the left atrium volume, aortic cross area long axis or LSPV long axis but poor correlation with the height, weight, surface area and vertebral body height of the patients. Four types of LAA ridge were identified: AI, AII, B and C with the distribution of 17.6%, 69.9%, 5.9% and 6.6%, respectively. The LAA had a significantly (P<0.05) greater distance from its orifice to the mitral ring in women than in men. The LAA had two filling and two emptying processes with the greatest volume at 45% phase but the least volume at 5% phase. The LAA maximal, minimal and emptying volumes were all significantly (P<0.05) positively correlated with the body height, weight and surface area, whereas the LAA ejection fraction had an inverse correlation with the LAA minimal volume but no correlation with the maximal volume. Conclusion: The LAA has substantially variable morphologies and relation with the adjacent structures, which may be helpful in guiding the LAA trans-catheter occlusion or catheter ablation procedures. [ABSTRACT FROM AUTHOR]

A framework approach was successfully performed to give a three-dimensional heterometallic compound exhibiting single-ion magnet (SIM) behavior. Enhanced SIM behavior was obtained by continuous application of diamagnetic-ion dilution and an external dc field. [ABSTRACT FROM AUTHOR]

Two unique heterometallic {Ln4Co} coordination polymers with infinite Ln4(OH)4]n8n+ chains have been successfully assembled, which represent the first example of heterometallic Ln–Co coordination polymers containing infinite lanthanide hydroxide chains. [ABSTRACT FROM AUTHOR]

A series of six-coordinate lanthanide complexes {(H3O)[Ln(NA)2]⋅H2O} n (H2NA=5-hydroxynicotinic acid; Ln=GdIII ( 1⋅Gd); TbIII ( 2⋅Tb); DyIII ( 3⋅Dy); HoIII ( 4⋅Ho)) have been synthesized from aqueous solution and fully characterized. Slow relaxation of the magnetization was observed in 3⋅Dy. To suppress the quantum tunneling of the magnetization, 3⋅Dy diluted by diamagnetic YIII ions was also synthesized and magnetically studied. Interesting butterfly-like hysteresis loops and an enhanced energy barrier for the slow relaxation of magnetization were observed in diluted 3⋅Dy. The energy barrier (Δ τ) and pre-exponential factor ( τ0) of the diluted 3⋅Dy are 75 K and 4.21×10−5 s, respectively. This work illustrates a successful way to obtain low-coordination-number lanthanide complexes by a framework approach to show single-ion-magnet-like behavior. [ABSTRACT FROM AUTHOR]

The efficient construction of CN double bonds has been achieved by the Ir-catalyzed intramolecular acceptorless dehydrogenative cross-coupling of tertiary amines and amides. An iridium/2-hydroxypyridine complex was identified as the highly efficient catalyst. A number of quinazolinone derivatives was prepared in excellent yields. An iridium-mediated CH activation mechanism is proposed. This finding provides an unprecedented strategy for the direct imidation of sp3 CH bonds. [ABSTRACT FROM AUTHOR]

The authors have provided their raw data; however, the Editors have not been able to verify the provenance of these data with the authors' institution. Editorial Expression of Concern to: I Scientific Reports i https://doi.org/10.1038/s41598-019-53715-z, published online 20 November 2019 The Editors are issuing an Editorial Expression of Concern for this Article because a concern has been raised that the imaging data presented originate from the patient database of a different institution from that described in the article. Xue-Jing Zhang, Wei-Li Hao, Dong-Hai Zhang and Bu-Lang Gao disagree with this statement. [Extracted from the article]

Xue-Jing Zhang, Wei-Li Hao, Dong-Hai Zhang and Bu-Lang Gao disagree with this statement. The authors have provided their raw data; however, the Editors have not been able to verify the provenance of these data with the authors' institution. [Extracted from the article]