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Er3+‐doped fluoride glass and fiber have been widely used in multiple fields such as mid‐infrared laser, visible laser, and amplifier. However, there is no unified conclusion on the thermal and optical properties with respect to varying concentrations of Er3+ doping. Furthermore, this is a paucity of systematic guidance on the preparation of Er3+‐doped fluoride glass and fiber. In this study, fluorozirconate fiberglass with Er3+ doping is systematically examined. Additionally, a preliminary explanation of the evolutionary behavior of glass devitrification, thermal properties, and fluorescence properties is provided. Energy transition models were built for 1.5 and 2.7 µm emissions in Er3+‐doped fluorozirconate at room temperature. Moreover, a suitable doping concentration is proposed based on the evolutionary behavior of thermal and optical properties. In this study, guidance on appropriate Er3+ doping concentration levels in fluorozirconate glass is provided and potential applications are explored. [ABSTRACT FROM AUTHOR]

We present a novel ZnO/Au/Ti/p-GaN self-powered ultraviolet photodetector (UVPD) featuring a sandwich structure of asymmetric interdigitated electrodes. This unique design skillfully integrates the conventional vertically-structured ZnO/p-GaN UVPD, asymmetric Au/ZnO/Au UVPD, and asymmetric Ti/p-GaN/Ti UVPD into a single device, which effectively enhances the separation and collection efficiency of photogenerated carriers while reducing their composite depletion through the coupling of the built-in electric fields of the Schottky junctions (ZnO/Au, p-GaN/Ti) and the heterojunction (ZnO/p-GaN), creating a synergistic enhancement in performance. At 0 bias, while achieving a fast response speed (0.98/0.63 ms), the ZnO/Au/Ti/p-GaN UVPD also shows improvements in light-to-dark ratios by 7.78, 15.79, and 20.0 times, and in responsivity peaks by 2.7, 4.12, and 152.84 times, compared to the ZnO/p-GaN UVPD, the MSM ZnO UVPD, and the MSM GaN UVPD, respectively. Our proposed sandwich structure of asymmetric interdigitated electrodes offers significant performance enhancement and a simple preparation process, and it can also be applied to other semiconductor heterojunctions, demonstrating wide practical application potential. This work provides a valuable strategy for the development of high-performance and low-cost self-powered UV photodetectors. [ABSTRACT FROM AUTHOR]

The colonization ability of Limosilactobacillus fermentum DALI02 and the promoting effect of fermented prebiotics have been studied. This study aims to evaluate the systemic immunomodulatory effects of DALI02 and DALI02 + Prebiotics on cyclophosphamide‐induced immunosuppressed rats. We found that DALI02 and DALI02 + Prebiotics, especially DALI02 + Prebiotics, exhibited significant restorative effects on the immunocompromised state in rats (p <.05). Specifically, both of them promoted the recovery of body weight and immune organ function, enhanced the proliferative capacity of immune cells, and effectively reduced the levels of interleukin 6 (IL‐6) and tumor necrosis factor‐α (TNF‐α). Furthermore, both of them significantly reduced the levels of lipopolysaccharide (LPS) and D‐lactic acid in the blood (p <.05). Principal coordinate analysis (PCoA), principal component analysis (PCA), and unsupervised cluster analysis revealed that DALI02 and DALI02 + Prebiotics group were more similar to the blank group at the genus level of the gut microbiota. At the level of short‐chain fatty acids (SCFAs), DALI02 + Prebiotics and blank group belonged to Cluster 3. These results suggested that the intervention with DALI02 and DALI02 + Prebiotics effectively modulated the structure of the gut microbiota, and DALI02 + Prebiotics restored the dysregulation of SCFAs. In summary, DALI02 and DALI02 + Prebiotics possess immunomodulatory functions, with the latter showing superior effects. [ABSTRACT FROM AUTHOR]

A 73-year-old male presented with erythema and papules all over the body with itching for 2 months, aggravated for 1 week. Eight months ago, he received immunotherapy with programmed cell death receptor 1 (PD-1) inhibitor for colorectal cancer, and 2 months ago, erythema and papules all over the body appeared, accompanied by severe itching. Dermatologic examination showed flaky erythema on the trunk and extremities, partially fused into a large area with scattered erythematous papules, scratches, and hyperpigmentation. Histopathology showed epidermal parakeratosis, hypertrophy of the stratum spinosum, and mild localized interspinous cell edema; capillary dilatation in the superficial dermis, predominantly peritubular lymphocytes, and occasional eosinophils. Diagnosis: immune checkpoint inhibitor-related skin toxicity (maculopapular rash with pruritus). After multidisciplinary discussion and informed consent, the patient was initiated on dupilumab therapy, administered as a 600 mg subcutaneous injection, followed by 300 mg doses every two weeks for a total of three treatments. The skin lesions and itching improved, and the patient was still under follow-up. % [ABSTRACT FROM AUTHOR]

An experimental study was undertaken to investigate the problem of the substantial variability in water content in unrotted sheep dung, which leads to a lack of universality and practicality in calibrating its discrete element simulation parameters. The stacking angle was used as the response value in these experiments. The objective of this study was to establish precise simulation parameters for the composting process. A model for water content-stacking angle was established using the cylinder-lifting technique, resulting in a correlation value of 0.997. Utilizing the Hertz–Mindlin with JKR bonding model, three EDEM particle models were developed, each with distinct particle sizes, based on the particle size distribution of sheep dung. The JKR surface energy was determined using the Plackett–Burman test, the steepest-climbing test, and the Box–Behnken test using a set of 10 parameters. A subsequent study was conducted on the JKR surface energy, rolling friction factor, and static friction factor utilizing the Plackett–Burman test and Box–Behnken test. A parameter model for stacking angle–discrete elements was developed that achieved a p-value below 0.0001 and a relative inaccuracy of 3.46% or less. The regression model for the water content–discrete element parameter was derived by combining the water content–stacking angle model with the stacking angle–discrete element parameter model. Validation of this model was conducted using both the pumping plate technique and the hopper approach, resulting in a relative error of 4.89% or less. The findings demonstrate that the specific characteristics of sheep manure may be accurately anticipated by considering its water content. This approach offers a valid and universally applicable way of predicting the specific characteristics of sheep dung in the simulation of composting equipment. [ABSTRACT FROM AUTHOR]

A debris flow, with terraced fields as the source area, broke out on June 25th, 2018 in the Xiaotuga area of Yunnan Province, China, and this kind of debris flow is rarely recorded. Two purposes in this study: (1) the influence of flow drag force on slope stability; (2) back-analyze the movement process of debris flow. First, the geological background and movement of this debris flow were described based on a field investigation. Then, drag force, calculated by the laminar flow theory, is added to the slope stability calculation model, which elaborates the initiation process of this disaster. Moreover, dynamic simulation software (DAN3D) was used to simulate the kinematic process of the debris flow with a variety of combination models. The study shows that the terrace area can quickly produce surface runoff and create a drag force under rainfall conditions, which is the essential reason for the initiation of debris flow. In addition, the use of the FVV (Frictional-Voellmy-Voellmy) model is found to provide the best performance in simulating this type of debris flow, which reveals that it lasts approximately 200 s and that the maximum velocity is 12 m/s. [ABSTRACT FROM AUTHOR]

This paper presents a novel approach known as the cross estimation network (CEN) for fitting the datasets obtained from psychological or educational tests and estimating the parameters of item response theory (IRT) models. The CEN is comprised of two subnetworks: the person network (PN) and the item network (IN). The PN processes the response pattern of individual respondent and generates an estimate of the underlying ability, while the IN takes in the response pattern of individual item and outputs the estimates of the item parameters. Four simulation studies and an empirical study were comprehensively and rigorously conducted to investigate the performance of CEN on parameter estimation of the two-parameter logistic model under various testing scenarios. Results showed that CEN effectively fit the training data and produced accurate estimates of both person and item parameters. The trained PN and IN adhered to AI principles and acted as intelligent agents, delivering commendable evaluations for even unseen patterns of new respondents and items. [ABSTRACT FROM AUTHOR]

The Inner Mongolia Autonomous Region, known for its famous Mongolian horses, faces significant environmental challenges due to the large-scale rearing of these animals, which produces a substantial amount of manure. If not managed effectively, this manure can lead to severe environmental pollution. The aim of this study was to investigate whether a small-scale intelligent aeration and heating composting system is effective in treating Mongolian horse manure, with the objective of enhancing composting efficiency and resource utilization to support sustainable agricultural development in the region. The equipment was utilized to treat a compost mixture of Mongolian horse manure and corn stover, allowing for an analysis of the changes in key indicators throughout the composting process. The results demonstrated that the equipment maintained high temperatures for up to eight days during the composting process, effectively inactivating pathogens and promoting the efficient decomposition of organic matter. The system also successfully controlled humidity to 12.7% and maintained oxygen concentration within the optimal range. Post-composting analysis revealed that the final compost contained 2.3% nitrogen, 1.3% phosphorus, and 1.2% potassium, with a pH of 6.4 and conductivity of approximately 5.2 mS/cm. Additionally, the carbon-to-nitrogen ratio decreased significantly from 27.3 to 15.9, indicating substantial organic matter degradation. Seed germination tests showed germination rates of 80%, 86%, and 75% for corn, mung bean, and wheat, respectively, with a final seed germination index of 104%. This study concluded that the small aeration and heating composting equipment is highly effective in treating Mongolian horse manure, producing high-quality organic fertilizers that significantly enhance soil fertility and demonstrate considerable potential for supporting sustainable agricultural practices and improving environmental management in the Inner Mongolia Autonomous Region. [ABSTRACT FROM AUTHOR]

Abnormal relaxation and contraction of intestinal smooth muscle can cause various intestinal diseases. Diarrhea is a common and important public health problem worldwide in epidemiology. Zingiber officinale Roscoe (fresh ginger) has been found to treat diarrhea, but the material basis and mechanism of action that inhibits intestinal peristalsis remain unclear. Metabolomics and serum pharmacology were used to identify differential metabolites, metabolic pathways, and pharmacodynamic substances, and were then combined with network pharmacology to explore the potential targets of ginger that inhibit intestinal peristalsis during diarrhea treatment, and the targets identified were verified using molecular docking and molecular dynamic simulation. We found that 25 active components of ginger (the six most relevant components), 35 potential key targets (three core targets), 40 differential metabolites (four key metabolites), and four major metabolic pathways were involved in the process by which ginger inhibits intestinal peristalsis during diarrhea treatment. This study reveals the complex mechanism of action and pharmacodynamic material basis of ginger in the inhibition of intestinal peristalsis, and this information helps in the development of new Chinese medicine to treat diarrhea and lays the foundation for the clinical application of ginger. [ABSTRACT FROM AUTHOR]

Wettability of droplets and droplet impinging on sparse micropillar-arrayed polydimethylsiloxane (PDMS) surfaces were experimentally investigated. For droplets wetting on these surfaces, the contact line density model combining stability factor and droplet sagging depth was developed to predict whether the droplets were in the Wenzel or Cassie–Baxter wetting state. It was found that droplets on the sparser micropillar-arrayed PDMS surfaces were in the Wenzel wetting state, indicating that a complete rebound cannot happen for droplets impinging on these surfaces. For the case of droplets impinging on sparse micropillar-arrayed PDMS surfaces, it was found that there existed a range of impact velocity for bouncing droplets on the micropatterned surfaces with a solid fraction of 0.022. To predict the upper limit of impact velocity for bouncing droplets, a theoretical model considering the immersion depth of liquid into the micropillar structure was established to make the prediction, and the lower limit of impact velocity for bouncing droplets can be obtained by balancing kinetic energy with energy barrier due to contact angle hysteresis. In addition, the droplet maximum spreading parameter was fitted and found to follow the scale law of We1/4. [ABSTRACT FROM AUTHOR]

In ultra–high voltage converter stations, the phenomenon of flashover along the outer insulation of dry hollow reactors made of epoxy (EP) /glass fiber (GF) composites poses a potential threat to the stability of the power system. To enhance its flashover performance under varying complex conditions, it is necessary to conduct in–depth research on the flashover mechanism of this material under different voltage forms. This study conducted tests on the flashover voltage, surface space charge distribution, and partial discharge (PD) parameters under varying AC–DC ratios and AC frequencies, and exploring their relationships. The results show that the DC content in the AC–DC ratio decreases, the flashover voltage decreases, the apparent total discharge of PDs increases, and the maximum surface space charge density decreases. The main influencing factor is the increase in the number of seed charges involved in gas ionization. Increasing the AC frequency, the flashover voltage decreases, the apparent total discharge increases significantly, and the surface charge density remains basically unchanged. The main reason is that the change in the number of alternating cycles further increases the number of seed charges. This study reveals the flashover mechanism of EP/GF composites under different voltage forms, which provides theoretical support for subsequent material modification. [ABSTRACT FROM AUTHOR]

The Inner Mongolia Autonomous Region is a crucial area in China with a significant advantage in animal husbandry, particularly in cattle and sheep farming. However, the disposal of the large quantities of manure produced during farming has severely impacted the industry's healthy development. Proper treatment of the manure can convert it into organic fertilizer beneficial to farmland; otherwise, it will cause substantial environmental pollution. This study focuses on existing composting equipment and addresses the issues of cattle and sheep manure mixture ratios and compost maturity evaluation. Through experiments on the mixture of cattle and sheep manure, the optimal ratio for converting cattle and sheep manure into organic fertilizer was determined. Additionally, a fuzzy mathematical evaluation model was employed, along with experimental data, to establish a comprehensive evaluation system for aerobic compost maturity based on multiple indicators, revealing the variation patterns of maturity levels under different mixture ratios. The test results revealed that the composting equipment effectively controls the composting process, shortens the composting cycle, ensures the complete decomposition of organic matter, and meets national standards for livestock and poultry manure treatment. Regarding temperature and humidity, oxygen concentration, seed germination rate, pH value, electrical conductivity (EC), nitrogen, phosphorus, potassium content, and carbon-to-nitrogen ratio, the mixed compost of cattle and sheep manure in various ratios met the relevant standards for agricultural application. Various ratios of organic fertilizers containing cattle and sheep manure significantly promoted the growth of maize, wheat, and mung bean crops. Specifically, the compost decomposition cycle was shortest when sheep and cattle dung were mixed at a ratio of 2:1, while it was longest for all cattle dung. Finally, a fuzzy mathematical comprehensive evaluation model was established by selecting four indicators: water content, carbon-to-nitrogen ratio, apparent score, and germination index. The study demonstrates that the equipment and method offer significant advantages in efficiently treating cattle and sheep manure and producing organic fertilizer, thereby providing strong support for the sustainable development of animal husbandry. [ABSTRACT FROM AUTHOR]

With the installation of rubber isolation bearings in the upper and lower ground layers, an isolated step-terrace structure was created. Considering the ultimate bearing capacity of the rubber bearing under tension as the critical condition, a comprehensive framework was established to evaluate the overturning failure mechanisms present in isolated step-terrace structures. The bound of nominal aspect ratio was identified as the principal control index within this framework, which incorporates critical parameters such as height ratio (α), width ratio (β), vertical tensile stiffness to compressive stiffness ratio (γ), seismic coefficient (k), and nominal vertical compressive stress (σ0) to provide a thorough analysis of the structural responses and potential failure scenarios. In order to further investigate this matter, a scaled model of an isolated step-terrace concrete frame structure featuring two dropped layers and a single span within an 8° seismic fortification zone was meticulously crafted at a 1:10 similarity ratio. Subsequently, a series of shaking table tests were conducted to analyze the structural response under seismic excitation. The findings indicate that: utilizing the bound of nominal aspect ratio as a metric to gauge the anti-overturning capacity of isolated step-terrace structures is a justified approach. In instances where the height ratio remains constant, the bound of nominal aspect ratio for both positive and negative overturning trended upward with an increase in the width ratio. Notably, the bound of nominal aspect ratio for positive overturning consistently registered lower values compared to that of the negative overturning, underscoring the heightened susceptibility of step-terrace structures to positive overturning. Moreover, in scenarios characterized by higher height and width ratios, the structural integrity remained unscathed by any overturning effects arising from insufficient tensile strength in rubber bearings. Furthermore, the bound of nominal aspect ratio exhibited an ascending trend as the seismic coefficient, nominal vertical compressive stress, and vertical tensile stiffness to compressive stiffness ratio decreased. The outcomes derived from the shaking table test not only confirm the impressive seismic performance of the structure, but also, by closely examining the instantaneous stress variations within the upper and lower isolation layers of the model, substantiate the existence of a positive overturning hazard in scenarios marked by higher seismic coefficients (k). This observation aligns seamlessly with the theoretical projections, thereby substantiating the efficacy of the structural overturning failure theory through direct empirical verification. [ABSTRACT FROM AUTHOR]

In this study, we propose a mechanochemical approach that combines mesoporous ZnO (m-ZnO) as a mechanoredox catalyst and silane-mediated atom transfer chemistry to achieve efficient hydrodehalogenation of organic halides. The reaction can be conducted under mild conditions without the use of a large amount of organic solvent. Substrates ranging from activated alkyl halides to unactivated aryl halides were converted to the corresponding debrominated hydrogenation products in moderate to excellent isolated yields (50–95%). In addition, m-ZnO can be recycled and reused without appreciable loss of catalytic activity. [ABSTRACT FROM AUTHOR]

Background: Actinobacillus pleuropneumoniae is a serious pathogen in pigs. The abundant application of antibiotics has resulted in the gradual emergence of drugresistant bacteria, which has seriously affected treatment of disease. To aid measures to prevent the emergence and spread of drug-resistant bacteria, herein, the kill rate and mutant selection window (MSW) of danofloxacin (DAN) against A. pleuropneumoniae were evaluated. Methods: For the kill rate study, the minimum inhibitory concentration (MIC) was tested using the micro dilution broth method and time-killing curves of DAN against A. pleuropneumoniae grown in tryptic soy broth (TSB) at a series drug concentrations (from 0 to 64 MIC) were constructed. The relationships between the kill rate and drug concentrations were analyzed using a Sigmoid Emax model during different time periods. For the MSW study, the MIC99 (the lowest concentration that inhibited the growth of the bacteria by ≥ 99%) and mutant prevention concentration (MPC) of DAN against A. pleuropneumoniae were measured using the agar plate method. Then, a peristaltic pump infection model was established to simulate the dynamic changes of DAN concentrations in pig lungs. The changes in number and sensitivity of A. pleuropneumoniae were measured. The relationships between pharmacokinetic/pharmacodynamic parameters and the antibacterial effect were analyzed using the Sigmoid Emax model. Results: In kill rate study, the MIC of DAN against A. pleuropneumoniae was 0.016 µg/mL. According to the kill rate, DAN exhibited concentration-dependent antibacterial activity against A. pleuropneumoniae. A bactericidal effect was observed when the DAN concentration reached 4–8 MIC. The kill rate increased constantly with the increase in DAN concentration, with a maximum value of 3.23 Log10 colony forming units (CFU)/mL/h during the 0–1 h period. When the drug concentration was in the middle part of the MSW, drugresistant bacteria might be induced. Therefore, the dosage should be avoided to produce a mean value of AUC24h/MIC99 (between 31.29 and 62.59 h. The values of AUC24h/MIC99 to achieve bacteriostatic, bactericidal, and eradication effects were 9.46, 25.14, and > 62.59 h, respectively. Conclusion: These kill rate and MSW results will provide valuable guidance for the use of DAN to treat A. pleuropneumoniae infections. [ABSTRACT FROM AUTHOR]

This study specifically focuses on the damping efficiency of a damped structure with additional viscous dampers. A two-layer steel frame structure with eight sets of viscous dampers is used to conduct a series of seismic simulation shaking table tests, including a non-damped structure without dampers and two damped structures with dampers placed at 1/2 and 1/6 of the beam span, respectively. By conducting these tests, the energy dissipation, force, and displacement of the damper, as well as the parameters of the structure such as floor displacement and acceleration, are obtained. The main damping efficiency indicators of the damped structure are calculated, including the additional damping ratio, inter-story displacement utilization rate, as well as the reduction rate of the vertex displacement and the base shear relative to the non-damped structure. The study shows that the viscous dampers exhibit full hysteresis loops and a strong energy dissipation capacity in the structure. The seismic response of the vertex displacement and base shear in the damped structure is significantly smaller than that in the non-damped structure. Under different seismic levels, including frequent earthquakes, occasional earthquakes, and rare earthquakes, the damping effect of the dampers placed at 1/2 of the beam span is significantly better than that placed at 1/6 of the beam span. For example, the additional damping ratio for the X-direction artificial wave REN is 19% and 11%, 20% and 13%, and 13% and 11%, respectively. The patterns for inter-story displacement utilization ratio, reduction rate of the vertex displacement, and reduction rate of the base shear are similar. The research findings strongly indicate that the damped structure with additional viscous dampers exhibits excellent damping efficiency. In future damping design, designers need to fully consider the placement of viscous dampers within the beam span. [ABSTRACT FROM AUTHOR]

Cr(VI) has been a carcinogen for organisms and a hazard to human health throughout the food chain. To explore a cost-effective and efficient method for removing Cr(VI), a Cr-resistant strain named LBA108 was isolated from the soil of a molybdenum-lead mining area. It was identified as Microbacterium through biochemical tests and 16S rDNA sequence analysis. Following 48 hours of incubation in LB culture medium containing 60 mg L−1 Cr(VI), the LBA108 strain exhibited reduction and adsorption rates for Cr(VI) at 96.64% and 15.86%, respectively. The removal mechanism was subsequently confirmed through Fourier-transform infrared spectroscopy, X-ray photoelectron spectroscopy and X-ray diffraction analysis. In an experimental setup, radish seedlings were cultivated as test crops under varying levels of Cr stress (ranging from 0 to 7 mg L−1) in a hydroponic experiment. With the inoculation of the LBA108 strain, the fresh weight of radish seedlings increased by 2.05 times and plant length increased by 34.5% under 7 mg L−1 Cr stress. In addition, the plant produced more antioxidant enzymes/enhanced antioxidant enzyme activities such as superoxide dismutase and catalase to prevent oxidative stress. Under Cr stress (6 mg L−1), the accumulation of Cr in rhizomes of radish seedlings increased compared to the control group by 91.44%, while the absorption of Cr by leaves decreased by 52.10%. These findings suggest that the LBA108 strain possesses bioremediation capabilities as a microbial-phytoremediation option for Cr-contaminated soil. [ABSTRACT FROM AUTHOR]

Multi-channeled nerve guidance conduit is a prospective way to repair peripheral nerve injury, which is still difficult to be fabricated. A novel extrusion-stretching method was utilized in this study to produce multi-walled carbon nanotubes (MWCNTs) loaded multi-channeled nerve conduits with improved flexibility and versatility. The channels and geography of the conduits were tunable. The results showed that the mechanical properties of the multi-channeled nerve conduits were suitable for peripheral nerve restoration. MWCNTs increased the biocompatibility of the multi-channeled nerve conduits. This study proved that the MWCNTs loaded multi-channeled produced by extrusion-stretching method have great potential to repair peripheral nerve injury. [ABSTRACT FROM AUTHOR]

Loess has unique water sensitivity due to its distinct formation environment. The structure of loess is undercompactness, weak cementation, and porousness. The water sensitivity of loess directly leads to many environmental problems and geological hazards, including subgrade subsidences, slope collapse or failures, and building cracking. To reveal the relationship between water sensitivity and loess structure, confined-compression collapsibility tests and triaxial-collapsibility tests were performed on loess in different areas. The collapsibility coefficient, porosity ratio, and collapsibility rate were analyzed. Results show that the collapsibility process of loess can be divided into three stages: wetting, softening, and settling. The collapsibility sensitivity of loess is determined primarily by its structural and hydraulic state. [ABSTRACT FROM AUTHOR]

This study examines the widespread practice of upstream tailings dam construction in metallurgical mines in China, conducting comprehensive testing and research on tailings from various depositional zones of the Caijiagou tailings pond. Analysis of the test results from three types of tailings reveals a systematic relationship between the mechanical characteristics of tailings and their depositional zones: the farther from the dam, the finer the tailings particles, categorized as silty clay tailing, silt tailing, and sandy silt tailing. Consistent patterns were observed in the consolidated-drained shear strength and consolidated-undrained effective shear strength of these tailings. Among these, sandy silt tailing exhibited the highest strength, whereas silty clay tailing displayed the lowest. The dynamic stress–strain relationships of all three tailings types are described using the Hardin equivalent viscous-elastic model, where the initial dynamic shear modulus and the maximum dynamic shear stress in the model increased with effective confining pressure. The damping ratios exhibited a three-stage trend with increasing dynamic strain: gradual increase, rapid growth, and then gradual stabilization. Under various consolidated stress conditions, the ratio of the damping ratio to the maximum damping ratio versus the reduction in dynamic shear modulus showed a favorable linear relationship. Under vibration conditions, the dynamic shear stress corresponding to tailings failure increased with higher effective confining pressure and consolidated stress ratio. Finally, this study summarizes the parameters and indicators related to the saturated tailings of iron mines used in the research. Our work provides a foundation and reference for the design of tailings dams and the development and utilization of abandoned tailings ponds. [ABSTRACT FROM AUTHOR]

When subjected to seismic activity, tall isolated buildings with a high aspect ratio are susceptible to overturning as a result of the failure of rubber isolation bearings under tension. In order to address this issue, a guided-rail tension device (GR) has been developed to enhance the tensile strength of rubber bearings. Furthermore, a novel guided-rail isolation rubber bearing (GR&RB) has been proposed as a potential solution. Quasi-static tests have been conducted to investigate the mechanical properties of the GR, as well as the GR&LNR600 and LNR600. Additionally, numerical finite element analysis has been employed to study the seismic response of the GR&RB under El Centro seismic action in a high-rise building with an aspect ratio of approximately 4. The experimental results suggest that the inclusion of GRs has a limited effect on the horizontal mechanical attributes of rubber isolation bearings. Nevertheless, it simultaneously enhances their tensile strength, demonstrating a significant augmentation of 4.23 times. Moreover, the mechanical behavior of the GR aligns with the Hook model. The numerical analysis suggests that the utilization of GR&RB can mitigate the tensile stress levels of rubber isolators. Furthermore, it is recommended to augment the elastic tensile stiffness of the GR while reducing the open value to enhance the tensile efficiency, with the potential to attain up to 75% efficiency in tensile performance. [ABSTRACT FROM AUTHOR]

The traditional social force model (SFM) in crowd simulation experiences difficulty coping with the complexity of the crowd, limited by singular physical formulas and parameters. Recent attempts to combine deep learning with these models focus more on simulating specific states of crowds. This paper introduces an advanced deep social force model, influenced by crowd states. It utilizes deep neural networks to accurately fit crowd trajectory features, enhancing behavior simulation capabilities. Geometrical constraints within the model provide control over varied crowd behaviors, adjustable to simulate different crowd types. Before training, we use the SFM to refine behaviors in real trajectories with excessively small distances, aiming to enhance the general applicability of the model. Comparative experiments affirm the effectiveness of the model, showing comparable performance to both classic physical models and modern learning-based hybrid models in pedestrian simulations, with reduced collisions. In addition, the model has a certain ability to simulate crowds with high density and diverse behaviors. [ABSTRACT FROM AUTHOR]

Achieving crowd formation transformations has wide‐ranging applications in fields such as unmanned aerial vehicle formation control, crowd simulation, and large‐scale performances. However, planning trajectories for hundreds of agents is a challenging and tedious task. When modifying crowd formation change schemes, adjustments are typically required based on the style of formation change. Existing methods often involve manual adjustments at each crucial step, leading to a substantial amount of physical labor. Motivated by these challenges, this study introduces a novel generative adversarial network (GAN) for generating crowd formation transformations. The proposed GAN learns specific styles from a series of crowd formation transformation trajectories and can transform a new crowd with an arbitrary number of individuals into the same styles with minimal manual intervention. The model incorporates a space–time transformer module to aggregate spatiotemporal information for learning distinct styles of formation transformation. Furthermore, this article investigates the relationship between the distribution of training data and the length of trajectory sequences, providing insights into the preprocessing of training data. [ABSTRACT FROM AUTHOR]

Offline Reinforcement Learning (RL) defines a framework for learning from previously collected static buffer. However, offline RL is prone to approximation errors caused by out-of-distribution (OOD) data and particularly inefficient for pixel-based learning tasks compared with state-based input control methods. Several pioneer efforts have been made to solve this problem; some use pessimistic Q-values approximation for unseen observation while others train a model to simulate the environment to train a model on previously collected data to learn policies. However, these methods require accurate and time-consuming estimation of the Q-values or the environment models. Based on this observation, we present offline RL methods with augmented data (ORAD), a handy but non-trivial extension to offline RL algorithms. We show that simple data augmentations, e.g. random translation and random crop, significantly elevate the performance of the state-of-the-art offline RL algorithms. Besides, we find that regularization of the Q-values can also enhance performance. Extensive experiments on the pixel-based input control-Atari demonstrate the superiority of ORAD over SOTA offline RL methods considering both performance and data efficiency, and reveal that ORAD is more effective for the pixel-based control. [ABSTRACT FROM AUTHOR]

Loess is a problematic type of soil with a worldwide distribution due to its collapsibility. The temporal discontinuity and spatial nonuniformity of its collapsibility can bring severe damage to building foundations, roads and water pipelines. In this study, the relationship between the saturation and K-G model parameters is established based on indoor compression tests and collapsible tests; the deformation characteristics of loess immersed in water are studied via a large-scale trial immersion pit test. The test site is a circular pit with a diameter of 10 m. The loess is immersed for 46 days; the variation in its accumulated settlement over time is recorded for 60 days, and its deformation process is simulated using a self-designed programme. Results show that for the stress–strain relationship of unsaturated loess, the relationship between equivalent suction and saturation can be obtained through the principle of deformation equivalence and fitted using the exponential function. The maximum vertical displacements calculated in the simulation and on-site immersion pit experiment are 0.036 m and 0.032 m, respectively. Such relatively good consistency indicates that the proposed method can reasonably predict the collapse behaviour of loess due to immersion. This research provides a reliable method for the numerical simulation of loess immersion deformation, and the parameters in the model only need to be determined by conventional experiments. [ABSTRACT FROM AUTHOR]

The revolutionary progress in cancer immunotherapy, particularly the advent of immune checkpoint inhibitors, marks a significant milestone in the fight against malignancies. However, the majority of clinically employed immune checkpoint inhibitors are monoclonal antibodies (mAbs) with several limitations, such as poor oral bioavailability and immune-related adverse effects (irAEs). Another major limitation is the restriction of the efficacy of mAbs to a subset of cancer patients, which triggered extensive research efforts to identify alternative approaches in targeting immune checkpoints aiming to overcome the restricted efficacy of mAbs. This comprehensive review aims to explore the cutting-edge developments in targeting immune checkpoints, focusing on both small molecule- and peptide-based approaches. By delving into drug discovery platforms, we provide insights into the diverse strategies employed to identify and optimize small molecules and peptides as inhibitors of immune checkpoints. In addition, we discuss recent advances in nanomaterials as drug carriers, providing a basis for the development of small molecule- and peptide-based platforms for cancer immunotherapy. Ongoing research focused on the discovery of small molecules and peptide-inspired agents targeting immune checkpoints paves the way for developing orally bioavailable agents as the next-generation cancer immunotherapies. [ABSTRACT FROM AUTHOR]

From August 21 to December 22, 2019, unexpected successive retrogressive failures occurred in a mild dip rock slope on the right bank of a newly constructed expressway in Yunnan, China, induced by slope cutting and rainfall. The unique failure kinematics of the event urged for a thorough back analysis of the interior and exterior factors to reveal the mechanisms of the initiation and process of this landslide. To this end, a comprehensive engineering geological and geotechnical study on this slide, including field investigations, data collections, and in situ and laboratory tests, was conducted and is presented in this study. It is revealed that active failure constrained by the rock joints in the sliding body and the underlying fully weathered mudstone (slip soil) is the essence of the mild dip rock slope failure. Furthermore, the study finds that an unbalanced shear stress region (USSR) can develop on the slip surface due to the strain softening of the slip soil and foot unloading. The propagation of the USSR may trigger a failure at its end along the rock joints in mild slopes, as opposed to the conventional limit equilibrium methods (LEM) that do not consider strain softening. Accordingly, a simple criterion is proposed to assess the active failure controlled by the rock joints, which can be easily used for a quick risk assessment of excavated dip rock slopes. These findings are expected to enrich the current failure predictive models for the excavated mild dip rock slopes and serve as a reference for design considerations. [ABSTRACT FROM AUTHOR]

The determination of the low-temperature plasma propagation of SF6/N2 in gas discharge will accelerate the application of SF6/N2 in advanced electrical equipment. This study investigates the positive streamer propagation characteristics of SF6/N2 by establishing a plasma discharge model and discusses the effects of SF6 ratio on the electron density, electric field, chemical reaction rates, ion concentrations, and streamer thickness and velocity. As the streamer propagates, the shapes of the electron density and electric field become "narrower and taller." Moreover, the ionization and attachment reaction rates increase, and the streamer thickness and velocity decrease with increasing SF6 mixing ratio and propagation time. As the SF6 ratio increases, the electric field distortion degree and particle mobility near the high-voltage electrode decrease due to the increase in the ionization and attachment rates. Consequently, the streamer velocity remains nearly unchanged, but the streamer thickness obviously decreases in the corona discharge process. In the streamer propagation process, the decrease in the streamer thickness and velocity with increasing SF6 ratio is attributed to the reduction in the electric field distortion and particle mobility, which stems from the increase in the DC breakdown voltage with the SF6 mixing ratio. The study results clarify the influence mechanisms of the SF6 mixing ratio on the particles' spatiotemporal evolution during streamer propagation. [ABSTRACT FROM AUTHOR]

Objective. To identify and quantify the active phenolic components in Lonicerae japonicae flos (LJF) for fever treatment and their mechanism of action using network pharmacology and molecular docking. Methods. Based on qualitative analysis of LJF, 194 phenolics were obtained, including 81 phenolic acids and 113 flavonoids. Gene Ontology and Kyoto Encyclopedia of Genes and Genomes pathway analyses were used to identify potential targets for these components to interact with fever. Molecular docking with microsomal PGE2 synthase-1, EP1, EP2, EP3, and EP4 targets was used to determine antipyretic components. The antipyretic efficacy of the main components was verified by in vivo experiments. Finally, high-performance liquid chromatography-tandem mass spectrometry was used to quantify the main antipyretic components of LJF. Results. Phenolics in LJF may prevent and treat fever by participating in calcium signaling, regulating TRP channels, and cAMP signaling. Luteolin-7-O-glucoside, apigenin-7-O-glucoside, 3,5-O-dicaffeoylquinic acid, luteolin, and other components have a good docking effect with PGE2 synthase-1 and its four subtypes. 3,5-O-dicaffeoylquinic acid, luteolin-7-O-glucoside, and apigenin-7-O-glucoside have good antipyretic effects in a yeast-induced pyrexia model. The content of these antipyretic components varies with the developmental period of LJF. Phenolic acids are the main components that distinguish the different developmental periods of LJF. Conclusion. The potential antipyretic components and molecular mechanisms of phenolics provide a basis for the traditional medicinal effects and future development and utilization of LJF. [ABSTRACT FROM AUTHOR]

The formation of peer attachment is vitally important for the mental health of adolescents. Additionally, converging evidences show that childhood emotional trauma leads to poor peer attachment during adolescence. However, little is known about the underlying mechanism accounting for the link between early emotional trauma and adolescent peer attachment. Therefore, the present study is intended to examine the relationship between childhood psychological maltreatment (CPM) and peer attachment among Chinese adolescents and reveal its underlying mechanism. In total, we collected data from 670 adolescents (36.5% males and 63.5% females, M age = 16.44 years, SD = 0.78) attending two Chinese high schools. These participants completed measurement scales for CPM (emotional abuse and neglect), peer attachment, and emotion regulation strategies, including cognitive reappraisal (CR) and expressive suppression (ES). The multiple mediation models showed that emotional neglect negatively predicted adolescent peer attachment but that emotional abuse did not. Furthermore, the two emotion regulation strategies, CR and ES, completely mediated the relationship between emotional abuse and peer attachment and partially mediated the relationship between emotional neglect and peer attachment. These findings extend the existing studies on adolescent peer attachment and elucidate how childhood emotional trauma negatively influences adolescent peer attachment. In addition, the present results provide implications for improving the peer attachment of adolescents. On one hand, appropriate family intervention should be implemented to reduce CPM. On the other hand, schools can focus on improving the peer attachment of adolescents by enhancing their emotion regulation. Specifically, adolescents should be taught how to use adaptive strategies, such as CR, to regulate negative emotions. [ABSTRACT FROM AUTHOR]

The high rates of misdiagnosis and untreated mortality with regard to Budd–Chiari syndrome (BCS) indicated the need to screen effective biomarkers. The aim of this study was to explore the function of extracellular vesicles (EVs) in patients with BCS as well as associated mechanisms. First, differentially expressed long non‐coding RNAs (lncRNAs) from EVs separated from serum between BCS and healthy controls were screened using microarray analysis. Second, the proliferation, migration and tube formation of human vascular endothelial cells (HUVECs) were detected after EVs treatment, along with vascular endothelial growth factor (VEGF) levels and inflammatory factors from the cell supernatant. Last, the overexpressed lncRNA was transfected into the cells to further explore the mechanisms involved. Extracellular vesicles of BCS patients have significantly higher levels of lncRNA MTUS2‐5 than healthy controls. Apparently, treatment with EVs from BCS or the ones transfected with plasmids that overexpress lncRNA MTUS2‐5 enhances proliferation, migration and angiogenesis capacity. The results were considerably better than those obtained from treatment with EVs from healthy controls or transfection with the normal control plasmid, which also elevated the level of VEGF and inflammatory factors. Furthermore, FOS and PTGS2 were potentially regulated by the lncRNA MTUS2‐5 transmitted by EVs. The lncRNA MTUS2‐5 in EVs plays an important role in angiogenesis in the Budd–Chiari syndrome. [ABSTRACT FROM AUTHOR]

The pronounced discrepancies in triggering intensities and failure modes observed in downhill progressive landslides pose significant challenges to their risk prediction and mitigation. Instead of focusing on an individual triggering event and/or failure mode as done in previous studies, this study systematically explores the instability issues of downhill progressive failure in long slopes. A unified analytical model is proposed to understand these observed discrepancies, in which criteria for the initiation of slope failure corresponding to all possible failure modes are formulated. Accordingly, a simple framework is established that is capable of predicting possible triggering thresholds and failure modes in advance. This would improve the accuracy of landslide hazard assessment, which is often reduced by the unknowns of the failure mechanisms and inaccurate assumptions of stress distribution along the failure surface. Furthermore, three practical cases are analyzed based on the established framework, and the findings are compared with field observations and existing studies, showing good consistency. This work gives an insight into a systematic understanding of the various failure phenomena in downhill progressive landslides and provides a reference for their risk assessment and subsequent decision-making. [ABSTRACT FROM AUTHOR]

The strength of loess in seasonal frozen soil areas decreases evidently due to the freeze-thaw cycle, which even leads to some engineering and geological problems. Fibre reinforcement is very effective in improving the mechanical properties of soil. Triaxial tests under different water contents, freezing temperatures, and number of freeze-thaw cycles were carried out for fibre-reinforced loess to study the ability of fibre reinforcement to improve the resistance of loess to freeze-thaw damage; scanning electron microscopy (SEM) was also conducted. The effects of freeze and thaw deterioration and reinforcement were discussed by comparing the strength parameters under different test conditions, and the influence mechanism of freezing temperature, number of freeze-thaw cycles, and reinforcement on loess strength was explained. Results show that a lower freezing temperature indicates a more evident decrease in strength after thawing. Under the action of the first five freeze-thaw cycles, the degree of decrease is more prominent. The fibre reinforcement can reduce the fragmentation of aggregates in loess, thereby effectively restraining the deterioration effect of loess during freeze-thaw cycles. Finally, the strength parameter prediction model under different freeze-thaw cycles of reinforced loess is established, thereby providing theoretical support for engineering application and numerical simulation of fibre-reinforced loess. [ABSTRACT FROM AUTHOR]

Comprehensive Summary: Mechanoredox chemistry that uses highly polarized piezoelectric materials as mechanoredox catalysts to promote redox reactions has emerged recently. It provides an alternative approach alongside the existing polymerization methods. Despite recent accomplishments, determining the quantitative relationship between the structure of ZnO and its catalytic performance for polymerization is still challenging. Herein, we prepared various ZnO crystals with different polar facets ratios to achieve efficient mechanically induced reversible addition‐fragmentation chain transfer polymerization (mechano‐RAFT). ZnO prepared from Zn(NO3)2 showed a high polar facet ratio of 1.66 and offered the highest catalytic activity among all ZnO samples. A near‐quantitative initiator efficiency of 99.5% and narrow molecular weight distribution were achieved for the polymerization of n‐butyl acrylate. Furthermore, the high chain‐end fidelity and chain extension capability were also evidenced by MALDI‐TOF MS and GPC analysis. This work highlighted the significant contribution of polar facets in ZnO to its catalytic activity and will guide the design of mechanoredox catalysis with superior catalytic performance in the future. [ABSTRACT FROM AUTHOR]

To reveal the dynamic characteristics of asphalt core embankment dams (ACEDs), we carried out a dynamic triaxial experiment on hydraulic asphalt concrete (HAC) under different temperatures (T = 4 °C, 10 °C, 16 °C, and 22 °C) and stress states (Kc = 1.0, 1.2, 1.4, and 1.6; σ3 = 0.5, 0.6, 0.7, and 0.8 MPa). The results indicate that HAC's maximum dynamic elastic modulus increased with decreasing temperature, increasing principal stress ratio, and increasing confining pressure. However, the damping ratio showed the opposite trend. Moreover, in order to study the deformation capacity of HAC, 300 cyclic loads were applied to some specimens. At a temperature of 22 °C, the specimens had a tendency to deform axially, but not significantly. With a decrease in temperature, the axial deformation tendency of the specimen gradually weakened or even disappeared. However, a small number of cracks appeared in the aggregate and between the asphalt and the aggregate of the specimen. In order to quantify the dependence of dynamic parameters on temperature, the temperature influence factor of the maximum dynamic elastic modulus and the temperature sensing factor of the damping ratio were defined. The variation in the temperature influence factor of the maximum dynamic elastic modulus with temperature can be described by a logistic function. The temperature sensing factor of the damping ratio increased with an increasing principal stress ratio and peripheral pressure. Finally, maximum dynamic elastic modulus and damping ratio computational models for the interaction of temperatures and stress states were developed using the normalization method. Upon comparison, the dynamic parameters were observed to be very close to those listed in the literature, which verifies the applicability of the computational models of the maximum dynamic elastic modulus and damping ratio. [ABSTRACT FROM AUTHOR]

We aimed to investigate the potential and mechanism of probiotics as digestive enzyme inhibitors to alleviate nonalcoholic fatty liver disease (NAFLD). We compared the level of NAFLD in rats before and after Limosilactobacillus plantarum grx16 intervention, as well as changes in gut digestive enzymes and inflammatory factors. L. plantarum grx16 inhibited the absorption of starch and triglycerides by inhibiting the activity of gut amylase and lipase to alleviate insulin resistance and reduce lipid accumulation in the body, thereby alleviating the inflammatory response, and thus alleviating NAFLD in rats. [ABSTRACT FROM AUTHOR]

To develop monoammonium phosphate (MAP) as a novel acid source for durable intumescent fire retardants (IFR), MAP microcapsules (MCMAPs) containing MAP as the internal core and melamine-formaldehyde (MF) as the external shell were prepared by in situ polymerization in this study. The influences of synthesis conditions (including reaction temperature, polymerization time, and reaction pH value) on the properties of obtained MCMAPs (MAP content, yield, morphologies, and thermal properties) were then investigated systematically. The morphologies, chemical structures, and thermal properties were characterized by optical microscopy, scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS), Fourier transform infrared (FTIR) spectroscopy, and thermogravimetry analyzer (TGA). The results show that MAP was well encapsulated by MF resin. No microcapsules are obtained at <55 °C or with polymerization times <1 h. Optimal preparation conditions of reaction temperature, polymerization time, and reaction pH value are 75 °C, 3 h, and 5.5, respectively. Those results provide process reference and theoretical basis for preparing MCMAPs and could promote the application of MAP microcapsules in wood flame-retardant materials. [ABSTRACT FROM AUTHOR]

With the development of ultrahigh voltage transmission line construction in northwest China, an increasing number of overhead transmission lines are crossing the loess regions. Ensuring the stability of electricity transmission towers and mitigating the risk of collapse are crucial prerequisites for the construction of transmission lines. Taking the 750 kV demonstration electricity transmission line in Guanting–Lanzhou East as an example, representative loess samples were selected for compression and collapsing sensitivity tests. Four foundation treatment schemes were designed, and the wetting deformation characteristics were investigated through numerical simulation of the rainfall infiltration process. Corresponding optimisation schemes were proposed. The collapsing process was divided into four stages through laboratory collapsing tests. The relationship function between saturation and the Duncan–Chang model parameters of loess was established, which was introduced into the finite element model to consider the rainfall infiltration process. The analysis of the displacement field, and loess saturation field with time after rainfall infiltration for the four schemes showed that adding a lime-stabilised soil cushion layer and waterproof layer to the inclined column foundation had the best effect. Given that the design scheme needs to consider safety and economy, the thickness of the cushion layer was optimised, thereby reducing the use of lime-stabilised soil by 20%. Research findings provide meaningful guidance for the design of transmission tower foundations in loess areas. [ABSTRACT FROM AUTHOR]

The dry-wet cycle is an important factor that causes slope instability and foundation settlement in loess regions. In order to study the effects of the dry-wet cycle on the structure and shear strength of loess, isotropic compression tests and triaxial shear tests were carried out on loess with different numbers of dry-wet cycles. The results show that the dry-wet cycles mainly reduce the cohesion of loess, and the most obvious decline is after the first cycle; however, they have no effect on the angle of internal friction of loess. The structural yield strength and structural parameters of loess can represent the structure of loess well, which gradually decrease with the increase in the number dry-wet cycles and water content. The initial yield surface is approximately an ellipse, which gradually shrinks with the increase in water content and dry-wet cycles. The structure and cohesion of loess have similar changes, and there is an obvious exponential function relationship between them. [ABSTRACT FROM AUTHOR]

We investigate the tensile failure processes of coal specimens under loading conditions by using both laboratory experiments and the 3D cohesive zone model (CZM) combined with the continuous-discontinuous method (CDM). Specifically, uniaxial, Brazilian, and triaxial tests were conducted in the laboratory to obtain the mechanical and strength properties of the coal such as Young's modulus, Poisson's ratio, fracture energy, cohesive strength, friction angle, uniaxial compression and shear strength. These properties were carefully calibrated prior to being taken as input parameters for the CDM modeling. The nucleation, growth and propagation of cracks in the coal were described by the CZMs, while the potential contact detection and interaction of fractured solids were treated via the penalty method. Furthermore, the parallel computation in Abaqus was employed to accelerate the calculations. All the results of our simulation were fairly consistent with the one obtained from the tensile tests in the laboratory. This study demonstrates that the CZM and CDM technique can be utilized together to obtain powerful insights into the failure mechanism of coal, which is also a powerful tool to clarify the collapse mechanism of coal block caving in the mining engineering design and scheme optimization. [ABSTRACT FROM AUTHOR]

This paper reviews the application of intelligent vision enhancement technology in the battlefield environment and explores new research directions. This paper mainly introduces three parts. First, we introduce a solution for enhancing the battlefield situation and using head-mounted displays for soldier combat. Second, we summarize three core technologies supporting intelligent vision enhancement technology: 3D environment reconstruction, tracking and registration, and situational awareness. Third, we summarize three application directions of intelligent vision enhancement technology on the battlefield. Finally, the problems and challenges in the research work are proposed, including current issues such as accurate battlefield situational awareness by augmented reality technology, multiperson collaborative management and data flow, as well as challenges in future battlefield situation enhancement and perception. The future development trend of intelligent vision enhancement technology on the battlefield has been prospected. Two meanings of this paper are as follows: the first is to review the research status of intelligent vision enhancement technology from the technical level and identify the key technical points that may restrict development in the future; the second is to analyze the advantages and disadvantages of intelligent vision enhancement technology from the level of battlefield application and the roles of users. In addition, this paper proposes how to take the lead and take initiative in future wars. [ABSTRACT FROM AUTHOR]

Long-term relief of indoor volatile pollution has become a competitive issue worldwide in both visible and dark environments. A novel self-luminous wood coating with carbon dots (CDs)/titanium dioxide (TiO2) nanomaterial coated SrAl2O4: Eu2+, Dy3+ (CDs/TiO2@SAO) composite was prepared for the long-term degradation of formaldehyde through a simple sol-gel method. The microstructure, chemical composition, ultraviolet-visible (UV-vis) spectra, and long-lasting fluorescence of the CDs/TiO2@SAO photocatalyst were analyzed to illustrate the mechanism for degrading formaldehyde. The obtained CDs with a particle size of ~2–7 nm have a good graphite structure and presented good absorption in visible light. In addition, owing to the synergistic effect of the CDs/TiO2 nanomaterial coating layer and the long-afterglow luminescence of the SAO phosphor, the CDs/TiO2@SAO composite can absorb a part of the visible light for photocatalytic degradation and store luminous energy efficiently at daytime so as to give out visible luminescence continuously for a few hours in the darkness. Furthermore, the functional wood coatings with CDs/TiO2@SAO composite presented continuous and efficient photocatalytic activity in the presence and absence of light exposure. The current research could provide a new strategy for designing an efficient photocatalyst for degrading formaldehyde pollution in the daytime with a visible light supply and in an indoor dark environment without an external light source. [ABSTRACT FROM AUTHOR]

The Purpose in Life test (PIL) is the best-known measure of meaning in life and has attracted widespread attention for decades. The current study aimed to determine the optimal version of the PIL and to investigate its psychometric properties in the Chinese context. This study was conducted with a Chinese college student sample (N = 986) using confirmatory factor analysis (CFA) and item response theory (IRT). The results indicated that Morgan and Farsides' two-factor solution (PIL-10) showed the best fit to the data among all fifteen PIL versions. In addition, the PIL-10 was demonstrated to be a cross-culturally sound measure with good reliability and validity and has high precision over most of the latent trait range. However, the findings from category response curves showed some problematic options in some items. These findings may serve as references for revision of the PIL-10. [ABSTRACT FROM AUTHOR]

Channel confluences are common in urban rivers and caused complex hydrodynamic conditions in the downstream section, significantly influencing the distribution of pollutants and the microbial community. So far, the principles of bacterial community assembly and their linkages with environmental factors are poorly understood. In the present study, the hydrodynamic and pollution conditions were investigated in a typical channel confluence of an urban river in the Yangtze River delta area, China, and their impacts on the bacterial community structure in the water and sediment were characterized using 16S rRNA gene high-throughput sequencing technology. Based on the results, the flow velocity was the crucial factor influencing the dispersal of nutrients, organic compounds, and bacterial communities in the river water. Moreover, the sediments exhibited higher α-diversity and bacterial richness for nitrogen and sulfur cycling than the water. In addition to flow velocity, the contents of total organic carbon, total phosphorus, and heavy metals determined the sediment bacterial communities at varying depths. The predictive analysis of functional gene category indicated differences between the water and sediment communities in metabolic potentials and pathogen risk and provided guidance for water pollution control and the eco-remediation of urban rivers. [ABSTRACT FROM AUTHOR]

In order to improve the performance of traditional ramjet, a ramjet based on pulse detonation (PD-Ramjet) instead of isobaric combustion was proposed. Several special-shaped detonation chambers which retained the characteristic structures of the dual-mode scramjet combustor were designed. Characteristic structures included the expansion channel and the cavity. The filling process and detonation initiation process of the stoichiometric hydrogen/air mixture under the incoming flow condition of the sub-combustion mode were studied in the detonation chambers with characteristic structures by two-dimensional numerical simulation method, and the influences of the characteristic structures on the filling process and detonation initiation process were analyzed. The simulation and analysis results indicated that the hydrogen concentration at both sides of the chamber near the outlet was low due to the structure of the expansion channel, and the pressure and velocity of the detonation wave decreased gradually after the expansion channel. The cavity had a significant influence on the filling process, which resulted in the uneven hydrogen concentration downstream the cavity, especially near the outlet of the chamber. The intensity of the detonation wave attenuated to a certain extent by reason of the cavity, where the peak pressure first decayed due to the sudden expansion of the flow path and then rose owing to the reflection at the cavity aft wall. [ABSTRACT FROM AUTHOR]

The failure patterns and retrogression distances in sensitive clays induced by river erosion are two significant factors of concern in landslide risk assessment. For the former, empirical criteria, based on past events and numerical results, can hardly produce a unified guideline and explain their complex mechanism. For the latter, the capacity of the river cross section is rarely considered in existing studies, even though the failed soil would deposit on the riverbed and further affect upslope failure extension. The present study proposes an analytical method to quantitatively assess the failure patterns and retrogression distance by combining the shear band propagation method (SBP) with limit analysis on active block failure. A closed‐form active earth pressure (CAEP) and the shape function of the failure surface are proposed with the variational calculus method (VCM), providing a tool to understand the transformation mechanism of the failure patterns. The criteria for initiation failure positions and stages are formulated following the competition results between the induced minimum slope‐parallel force by foot unloading and the proposed CAEP. Further, the terminal retrogression distance is given considering two possible river cross sections. The proposed CAEP solution is validated against Buss's solution and further applied to a parametric study on the failure patterns. Finally, three practical cases are analyzed with the proposed method, and the predictions are shown to agree well with the field observations. [ABSTRACT FROM AUTHOR]

Slate with inherently transverse isotropy is abundant in metamorphic rock, in buildings, and in geotechnical engineering worldwide; the tensile and shear fracture behavior of layered slate is vital to know for engineering applications. In this paper, the Brazilian and semi-circular bend (SCB) tests of layered slate were performed. The fracture characteristics of the slate were investigated by numerical simulations developed by the hybrid finite and cohesive element method (FCEM). Results showed that the measured experimental tensile strength, and mode I fracture toughness of layered slate all showed a typical V-type trend as the bedding angle increased from 0° to 90°, and with divider type. The developed empirical relationship between tensile fracture toughness and tensile strength KIC = 0.094σt + 0.036 fitted experimentally and strongly correlated. The mechanical response and fracture patterns predicted by FCEM agreed well with those of the laboratory experiments. Moreover, the shear fracture behavior and mode II fracture toughness of the layered slate were explored by systematic numerical simulations. Research results provide potential insights for further prediction and improvement of the complex fracture behavior of anisotropic rock masses for rock engineering. [ABSTRACT FROM AUTHOR]

To create a green, safe, and aldehyde‐free indoor heating environment, an eco‐friendly emulsion polymer‐isocyanate (EPI) adhesive was applied to the preparation of electrothermal plywood with built‐in carbon fiber paper. The optimized process parameters of electrothermal plywood were 0.9 MPa, 120°C, 6 min, and 200 g/m2 for hot‐pressing pressure, temperature, time, and glue spread amount, respectively. After water immersion for 24 h, the bonding strength of wet‐treated electrothermal plywood decreased to 0.89 MPa. The pull‐out cracks of the carbon fiber paper were the main fracture form of the wet‐treated electrothermal plywood, and the wood failure percentage was 0%–10% under the tensile load. Hydrolysis of the adhesive layer of the wet‐treated electrothermal plywood occurred. The relative C and N contents in the wet‐treated electrothermal plywood decreased by 6.1% and 25.3%, respectively. Moreover, the resistance of the wet‐treated electrothermal plywood increased by 273.4% because the internal conductive path was interrupted during the intrusion of the water molecules. The highest electric‐to‐radiant transfer efficiency of the electrothermal plywood was 72.4%, with a power density of 200 W/m2. In conclusion, wet treatment has a significant effect on the bonding strength and electrothermal performance of the electrothermal plywood bonded with EPI adhesive. [ABSTRACT FROM AUTHOR]