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1. Flow Characteristics of Thermo-Responsive Microspheres in Microchannel during the Phase Transition.

Author

Ming-Yu Zhou, Rui Xie, Xiao-Jie Ju, Ze-Lin Zhao, and Liang-Yin Chu

Subjects
CHEMICAL engineering, MICROSPHERES, MICROREACTORS, CLUSTERING of particles, CHEMICAL processes, CHEMICAL process control, DRUG delivery systems, MANAGEMENT
Abstract

The article discusses research on mono-disperse poly(n-isopropylacrylamide) (PNIPAM) microspheres to evaluate their flow and agglomeration in microchannel during phase transition. The research has applications in various fields including controlled drug-delivery systems and chemical separation. The article delineates experimental conditions, temperature and phase-transition effects on microsphere aggregation, and key parameters that affect flow and aggregation. It states that operating conditions can be designed to stop microsphere aggregation at a particular point in the microchannel.

Published
2009
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