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1. Pathoimmunological analyses of fatal E11 infection in premature infants.

Author

Wei Luo, Lixia Wang, Zhengrong Chen, Ming Liu, Yixue Zhao, Yucan Wu, Bing Huang, and Ping Wang

Subjects
PREMATURE infants, PATHOLOGICAL physiology, INFECTION, NEWBORN infants
Abstract

E11 causes acute fulminant hepatitis in newborns. We investigated the pathological changes of different tissues from premature male twins who died due to E11 infection. The E11 expression level was higher in the liver than in other tissues. IP10 was upregulated in liver tissue in the patient group, and might be regulated by IFNAR and IRF7, whereas IFNα was regulated by IFNAR or IRF5. [ABSTRACT FROM AUTHOR]

Published
2024
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