1. Comparison of percutaneous microwave/radiofrequency ablation liver partition and portal vein embolization versus transarterial chemoembolization and portal vein embolization for planned hepatectomy with insufficient future liver remnant.
- Author
-
Ye, Tai-Wei, Fu, Tian-Wei, Du, Cheng-Fei, Yue, Ru-Chi, Jiang, Qi-Tao, Zhong, Zhi-Hang, Zhao, Qin, Zhang, Cheng-Wu, Liu, Jie, Liu, Jun-Wei, Luo, Zu-Yan, Fan, Xiao-Ming, Hong, De-Fei, Cheng, Jian, and Xiao, Zun-Qiang
- Subjects
PORTAL vein ,SURGICAL complications ,CATHETER ablation ,OVERALL survival ,SURVIVAL rate ,CHEMOEMBOLIZATION - Abstract
Background: In China, both percutaneous microwave/radiofrequency ablation liver partition plus portal vein embolization (PALPP) and transarterial chemoembolization (TACE) plus portal vein embolization (PVE) have been utilized in planned hepatectomy. However, there is a lack of comparative studies on the effectiveness of these two techniques for cases with insufficient future liver remnant (FLR). Methods: Patients were categorized into either the PALPP group or the TACE + PVE group. Clinical data, including FLR growth rate, complications, secondary resection rate, and overall survival rate, were compared and analyzed for both groups retrospectively. Results: Between December 2014 and October 2021, a total of 29 patients underwent TACE + PVE (n = 12) and PALPP (n = 17). In the TACE + PVE group, 7 patients successfully underwent two-stage hepatectomy, while in the PALPP group, 13 patients underwent the procedure (two-stage resection rate: 58.3% vs. 76.5%, P = 0.42). There were no significant differences in postoperative complications of one-stage procedures (11.8% vs. 8.3%, P > 0.05) and second-stage resection complication (0% vs. 46.2%, P = 0.05) between the TACE + PVE and PALPP groups. However, the PALPP group demonstrated a shorter time to FLR volume growth for second-stage resection (18.5 days vs. 66 days, P = 0.001) and KGR (58.5 ml/week vs. 7.7 ml/week, P = 0.001). Conclusions: Compared with TACE + PVE, PALPP results in a more significant increase in FLR volume and a higher rate of two-stage resection without increasing postoperative complications. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF