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Camellia oleifera Abel., as one of the four major woody oilseeds, has a high economic value, and the wild C. oleifera genes, whose distribution area is located at the northern edge, are abundant and are valuable resources for C. oleifera breeding. In this study, a total of 341 wild C. oleifera populations were sampled from 11 different localitions in Xinxian County, the hinterland of the Dabie Mountains in the northern margin of the distribution of C. oleifera in China, and 16 pairs of simple sequence repeat (SSR) molecular markers were used to analyse the genetic diversity. Using these 16 pairs of primers to detect the genetic diversity of the wild C. oleifera population, 174 alleles were amplified. The average number of alleles (Na) was 10.875, the average expected heterozygosity (He) was 0.739, the observed heterozygosity (Ho) was 0.718, and the average polymorphic information index (PIC) was 0.739. The 11 wild C. oleifera populations in Xinxian County had high genetic diversity, and the average expected heterozygosity (He) among populations was 0.735. The molecular variance showed that the genetic variation mainly came from within the population, accounting for 88.21% of the total variation. The genetic differentiation coefficient Fst between populations was small, with an average of only 0.04. According to the results of Structure and principal cordinate analysis (PCoA) and cluster analysis, these 11 populations could be roughly divided into two categories. The Mantel test preferentially clustered some populations close to each other, but there was no significant correlation between genetic distance and geographical distance. We provides a theoretical basis for the rational development and utilisation of wild C. oleifera resources in the future and provide a scientific and technological method for future breeding. [ABSTRACT FROM AUTHOR]

Purpose: There is evidence that long-term vascular risk remains increased in patients with hyperthyroidism even after normalization of thyroid function, and the mechanisms that regulate this risk are unclear. The aim of this study was to assess how visceral fat area and subcutaneous fat area change after hyperthyroidism treatment, and to further explore the relationship between thyroid hormones, abdominal fat area (visceral fat area and subcutaneous fat area), and lipids. Patients and Methods: 50 patients with newly diagnosed Graves' disease were selected. Anthropometric parameters (weight, height, body mass index, waist circumference, neck circumference), laboratory parameters (thyroid hormones, lipid metabolism indices), abdominal fat area (visceral fat area and subcutaneous fat area), and drug dose were collected. Measurements were made at baseline, 6 and 12 months after treatment. We used linear mixed-effects models for analysis. Results: The results showed that the following indexes changed significantly at different time points: visceral fat area, subcutaneous fat area, free triiodothyronine, free thyroxine, thyroid stimulating hormone, total cholesterol, high-density lipoprotein, low-density lipoprotein, body weight, neck circumference, body mass index, waist circumference, and drug dose (All P< 0.001). We found that free triiodothyronine and free thyroxine were significantly negatively associated with abdominal fat area (P< 0.01). There was no significant correlation between drug dose and abdominal fat area (P> 0.05). Total cholesterol and low-density lipoprotein were significantly positively associated with abdominal fat area (P< 0.01). However, high-density lipoprotein (P=0.06) was not correlated with abdominal fat area. Moreover, the results showed a significant negative correlation between thyroid hormones and lipids (P< 0.001). Conclusion: After anti-thyroid medicine treatment, patients had elevated visceral fat area and subcutaneous fat area and altered lipid profiles. These changes may be one of the reasons why metabolic and cardiovascular diseases remain increased after thyroid function is restored. [ABSTRACT FROM AUTHOR]

Background: Allergic bronchopulmonary aspergillosis (ABPA) primarily complicates the course of asthma, cystic fibrosis, and chronic obstructive pulmonary disease (COPD). Mortality data of ABPA and the difference in all-cause mortality between ABPA with and without COPD are not available. Objective: We investigated the difference in all-cause mortality between ABPA with and without COPD. Methods: A retrospective review was performed among patients with the diagnosis of ABPA at Peking University People's Hospital between January 2010 and March 2022. Logrank test was performed to investigate the difference between all-cause mortality for ABPA with and without COPD and Cox regression analysis was performed to investigate the independent risk factors for all-cause mortality in patients with ABPA. Results: Sixty-one patients with ABPA were enrolled in this study. The follow-up duration was 50.38 months (3– 143 months). In the COPD group, 7 patients died (7/10), while in the non-COPD group, 4 patients died (4/51). The 1-year survival rates of ABPA with and without COPD were 60% and 97.8%, respectively. The 5-year survival rates of ABPA with and without COPD were 40% and 94%, respectively. The Cox regression analysis showed that higher C-reactive protein (CRP) (HR = 1.017, 95% CI 1.004– 1.031, P = 0.013) and complicating COPD (HR = 8.525, 95% CI 1.827– 39.773, P = 0.006) were independent risk factors associated with mortality in patients with ABPA. Conclusion: The all-cause mortality for ABPA with COPD is higher than that for ABPA without COPD. Higher CRP and complicating COPD are independent risk factor for mortality in patients with ABPA. [ABSTRACT FROM AUTHOR]

Slope farmland is prone to soil erosion, especially in sub/tropical regions. However, our understanding of near-surface hydrology characteristics and their controlled factors in red soil sloping farmland remains limited. Here, we conducted simulated rainfall experiments to assess the impact of rainfall pattern, straw mulching, and soil structure on near-surface hydrological processes of red soil sloping farmland of southern China. Results showed that: (1) short duration-high intensity rain caused greater surface runoff and sediment production than did long duration-low intensity rain, whereas the variation pattern of subsurface flow exhibited the opposite trend; (2) tillage behavior could weaken the surface runoff intensity and promote the development of subsurface flow; (3) straw mulching increased the water infiltration rate and associated subsurface flow production (increased by 1.33~12.71 times), and thus reduced the surface runoff production (reduced by 99.68~100%). These findings highlight the crucial roles of rainfall pattern and straw mulching in regulating the spatial distribution pattern of rainwater and suggest that straw mulching can effectively reduce soil erosion via accelerating water infiltration and subsurface flow form in slope farmland of soil erosion in southern China. [ABSTRACT FROM AUTHOR]

Unsustainable agricultural land use will lead to an increased risk of soil erosion and soil degradation. However, few studies have investigated impacts of changes in root and soil properties on the soil detachment process. Therefore, we investigated the effects of agricultural land use on the relative contribution of root and soil properties to soil detachment capacity. Soil samples were collected from six different land use types and subjected to flow scouring under six shear stresses ranging from 4.98 to 16.37 Pa. Agricultural land use influenced root distribution and soil properties in the soil surface layer. Root length density, root surface area density, and root volume density in orchards with no cover, orchards with grass cover, and farmland were less than those of grassland samples. Different land use types affected soil detachment capacity. Bare land, farmland, and orchards with no cover were more vulnerable to erosion, while forest, orchard with grass cover, and grassland showed little soil detachment. Soil detachment capacity decreased exponentially with increasing soil bulk density, aggregate stability, organic matter, and root mass density. The root mass density and aggregate stability had the greatest contribution to the soil detachment capacity. Agricultural land use increases the risk of soil erosion; a groundcover management strategy, such as planting grass in orchard, could effectively increase the fine root distribution and aggregate stability to control soil erosion. [ABSTRACT FROM AUTHOR]

Background: This study aimed to investigate the characteristics and extent of glycometabolism impairment in patients with adrenal diseases, including Cushing syndrome, primary aldosteronism, pheochromocytoma, and nonfunctional adrenal incidentaloma. Methods: This study enrolled thirty-two patients with adrenal diseases as adrenal disease groups and eight healthy individuals as healthy controls. Blood glucose levels were indicated by glucose concentration in interstitial fluid, which was documented using flash glucose monitoring system. According to flash glucose monitoring system data, parameters representing general blood glucose alterations, within-day and day-to-day glucose variability, and glucose-target-rate were calculated. Furthermore, blood glucose levels at nocturnal, fasting, and postprandial periods were analyzed. Besides, islet β-cell function and insulin resistance were assessed. Results: Analysis of flash glucose monitoring system-related parameters indicated impaired glycometabolism in patients with adrenal diseases compared with that of healthy controls at general blood glucose, within-day and day-to-day glucose variability, and glucose-target-rate levels. Furthermore, the dynamic glucose monitoring data revealed that significantly affected blood glucose levels compared with that of healthy controls were observed at postprandial periods in the Cushing syndrome and primary aldosteronism groups; at nocturnal, fasting and postprandial periods in the pheochromocytoma group. Significant insulin resistance and abnormal β-cell function were observed in the Cushing syndrome group compared with that in healthy controls. Conclusion: Adrenal diseases can negatively affect glucose metabolism. Patients diagnosed with adrenal diseases should receive timely and appropriate treatment to avoid adverse cardiovascular events linked to hyperglycemia and insulin resistance. [ABSTRACT FROM AUTHOR]

In this work, a series of polyethyleneimine (PEI) impregnated metal-organic framework (UiO-66) with varying PEI loadings were prepared and applied as sorbents to capture phosphate ions from water. As indicated by SEM and XRD analysis, PEI was dispersed on the outer surface and the inner pores of UiO-66. At 9.45% PEI loadings (UiO-66-3), the saturated adsorption capacity of phosphate reached 73.15 mg P/g at 298 K, which is superior to most sorbents ever reported. UiO-66-3 could sequestrate phosphate over a wide pH range from 2.0 to 7.0 with high efficiency. The sorption toward phosphate reached equilibrium in 50 min. Unlike commercial anion exchanger IRA-900, UiO-66-3 still exhibited high removal toward phosphate even large amount of coexisted anions were present. Successive sorption assay demonstrated that the removal efficiency of UiO-66-3 toward phosphate remained constant after six cyclic runs. All the above results indicated the great potential of UiO-66-3 as a promising sorbent for the decontamination of water from phosphate. [ABSTRACT FROM AUTHOR]