Search

Introduction: Concussion symptoms following a traumatic accident are both common and known to adversely affect mental health and recovery in patients with traumatic brain injury. Depression, highly prevalent among patients with traumatic brain injury, is also associated with the important factors of sleep quality and resilience. However, the mediator and moderator roles of depression following concussion in patients with traumatic brain injury have been underexplored. The aims of this study were to investigate the mediating role of sleep quality in the relation between concussion symptoms and depression and to examine the moderating effect of resilience on this mediated model. Design: Cross‐sectional pretest data analysis of a randomized controlled trial. Methods: A total of 249 adult patients with mild traumatic brain injury (Glasgow Coma Scale 13–15) at admission following brain injury were surveyed at a medical center in Taipei, Taiwan. The outcome variables were concussion symptoms (Rivermead Post‐Concussion Symptom Questionnaire), sleep quality (Pittsburgh Sleep Quality Index), resilience (Resilience Scale for Adults), and depression (Beck Depression Inventory II). These data were analyzed using moderated mediation regressions with the SPSS PROCESS macro. Results: In patients with mild traumatic brain injury, there was a significant positive relation between concussion symptoms and depression, of which sleep quality was a significant mediator. Additionally, resilience had a negative moderating effect on the relations between sleep quality and depression. Patients with less resilience showed a stronger negative effect of sleep quality on depression. Conclusion: Our findings suggest that ameliorating both concussion symptoms and sleep disturbance is important for reducing the risk of depression in patients with mild traumatic brain injury, especially in those patients with less resilience. Clinical Relevance: It is essential for clinical nurses to develop interventions for patients with mild traumatic brain injury that will improve their sleep quality, while strengthening their resilience, to alleviate depression. [ABSTRACT FROM AUTHOR]

Traumatic brain injury (TBI) is a major cause of disability and mortality worldwide. People with TBI exhibit poor quality of life (QOL). Exercise is considered a possible intervention for improving cognitive function and mood, helping improve QOL in patients with TBI. According to our review of the relevant literature, meta-analyses have yet to explore the effect of exercise on QOL in patients with TBI. To determine by meta-analysis of relevant studies whether physical exercise could promote QOL in patients with TBI. A systematic review and meta-analysis of intervention studies involving physical exercise for improving QOL outcomes in TBI populations were conducted according to the PRISMA guideline. Our inclusion criteria were as follows: being randomized or nonrandomized controlled trials with quantitative designs that included patients diagnosed with TBI. Thus, six studies met the inclusion criteria. The interventions in four of the six studies had statistically significant effects on QOL improvement. Our meta-analysis revealed a moderate effect size of physical exercise on QOL promotion in patients with TBI. For TBI, exercise seems to improve QOL. More research with long-term follow-up should be conducted to assess the effect of exercise on patients with TBI. [ABSTRACT FROM AUTHOR]

Regional cerebral blood flow (rCBF) increases after moderately intense exercise and is significantly correlated with cognitive function. However, no intensity-based physiological indicator for enhancing rCBF during low- to-moderate-intensity exercise has been proposed. The purpose of this study was to develop a physiological indicator housed in a wearable device to determine whether low-to-moderate intensity walking can increase rCBF. A cross-sectional study with four parallel arms was performed. Each of 114 participants was randomly assigned to either the moderate, low-to-moderate, low, or very low walking intensity groups. A novel dynamic cardiac force meter (CFM) was used to quantify walking intensity. Heart rate and hemoencephalography (HEG) were measured during each phase of the session. Compared to baseline, HEG significantly increased in both the submaximal exercise and recovery phases in members of the low-to-moderate intensity group but not the very low intensity group. Low-to-moderate intensity walking improves prefrontal cerebral blood oxygenation. The present results demonstrate the usefulness of a dynamic CFM housed in a wearable device for quantifying the intensity of walking exercise aimed at increasing prefrontal blood oxygenation. The results of the study may help guide further development of exercise strategies for brain disease patients and the ageing population. [ABSTRACT FROM AUTHOR]